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The map label for this gene is secD [H]

Identifier: 28572648

GI number: 28572648

Start: 538281

End: 539903

Strand: Reverse

Name: secD [H]

Synonym: TW499

Alternate gene names: 28572648

Gene position: 539903-538281 (Counterclockwise)

Preceding gene: 28572649

Following gene: 28572647

Centisome position: 58.31

GC content: 47.2

Gene sequence:

>1623_bases
GTGGTTGTCCTTCTCCTTCTTTCTCTAGATATCTGGCAGGTCTTTTTCTCTGGCAGTACCTTTCTGCCGAAGCTCGCCCT
AGATCTTGAGGGCGGAACACAGATTGTCTTGCGTGCTAAGGCTGCCGAAAAGGAGATTACCAGCGAACAGCTCCAGCAGG
CAGTTGCTATTATTCGCAATAGGGTTGATTCAAGCGGAATCTCCGAGGCAGAGATTTCCGTCCAGGGGAGTACAAATATA
TCCGTATCTATTCCTGGCACACCCTCTCAGGAGGTTTATGACAGGATTCGCTCTTCTTCCAAGATGGATATGCGTGCTGT
TTTACTAACGAAGCCCATTCAGCATGCTGCTATGAATGAAGGGTCCACACATGCAGGTTCGACAGCCAGCGCCGCGATTG
GTGATAAGAATGCCACACGTGGGTCGCCGAAATCTAGCGAGCATCGGAAAAATATTCCCAAGACTCCACACGATACGTCT
GGCATGATTCCTTCTCCGCGCCCAAAAAATGGCAGCGATATGGCGTGGATTACGAAATACTGGCGCGATCGTTTTGATTC
ACACAATTGTAAAGATAACGCCGGGGACAGTACCCCAGATAATCTTCCCCTTGTTGTGTGTGATCAGTACGGAACCACAA
AGTATCTACTGGGACCTGTTGAAGTAAGCGGAACTGATATATCAAGAGCAGTGGCAGATCCCGTTTCATCGCATTTTGCA
GGTGCTTCTATTGGCTGGGGTGTTACGATTACCTTTAACGCGCACGGTGGTGAGAAATTTAAGGATGTGTCAAATCGCCT
TATATCTCTTGCGGCCCCCAGAAATCAGTTTGCAGCCGTTTTGGATGGAGTTGTTATAACAGCTCCTGAAGTCAGGGGTG
TTACCAGTAATCCGCAGATAACGGGTAACTTCAACCAGACAACTGCCACTGCTCTTGCCAGTCAGCTTAGTTTCGGGTCT
CTTCCAGTTAGCTTTGAGGTCCAGTCAAGCGAAAATATTTCCGCCACCCTAGGATCGAGCCAGTTACAAAGCGGAATCTT
GGCTGGGATCCTGGGAATGATTCTTGTTGTGGTTTATTCATTGTTTCAGTACCGACTTCTTGGGCTCTTGACAGTATCAT
CTCTCATTTGCTCGGCTATTGTTACTTATCTTGTAATAACCTTCCTTTCCTGGCAAAACGGGTATCGTCTCTCTTTAGCT
GGTGTTGCCGGTCTGATTGTTGCAATTGGTATTACTGCCGATTCCTTCATAGTGTATTTTGAACGGGTTAAGGATGAGTT
ACGAGAAGGAAGGGATATTGTCCGTGCAGTGGATCGTGGGTGGTCACGCGCACTGCGGACAATTTGCGCCTCTGATGCAG
TGAACTTTTTGGCTGCTATTGTTTTGTTTTTAGTCGCGGTGGGAAGCGTAAAGGGTTTTGCGTTTACCCTTGGCCTTACA
ACTCTTGTTGACTTGCTTGTTGTTGTATTCTTCACGCATCCCGTTTTGCAGTATCTTTCCCACAGTAGTTTCTTTACTCG
GAAATACAGTGGTTTGAATGTTAAATCAGCTGTTTACAGGGGTAGGCTTATGACGCGTGATAAATCTCAAAAGACGATAG
CAGAGCGAAAGGCCGGGCATTAA

Upstream 100 bases:

>100_bases
ACGTTCTGCAAGGGATAAGTAAGGCTTCTGCAGAATCTCGTGAATGCATAAATTCCCACCTGCAATAAGAAAGGCGAGGA
GATCTCTTGGCATCCTGGCT

Downstream 100 bases:

>100_bases
TGGCGTGGTTTGCGCGGTTTAGTGACGATCTTTACAGTGGACGGAGATCAATAGACTTCGTTGGTCGGTATAAGATATGG
TATTCCGCGTCTTTTGTTAT

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MVVLLLLSLDIWQVFFSGSTFLPKLALDLEGGTQIVLRAKAAEKEITSEQLQQAVAIIRNRVDSSGISEAEISVQGSTNI
SVSIPGTPSQEVYDRIRSSSKMDMRAVLLTKPIQHAAMNEGSTHAGSTASAAIGDKNATRGSPKSSEHRKNIPKTPHDTS
GMIPSPRPKNGSDMAWITKYWRDRFDSHNCKDNAGDSTPDNLPLVVCDQYGTTKYLLGPVEVSGTDISRAVADPVSSHFA
GASIGWGVTITFNAHGGEKFKDVSNRLISLAAPRNQFAAVLDGVVITAPEVRGVTSNPQITGNFNQTTATALASQLSFGS
LPVSFEVQSSENISATLGSSQLQSGILAGILGMILVVVYSLFQYRLLGLLTVSSLICSAIVTYLVITFLSWQNGYRLSLA
GVAGLIVAIGITADSFIVYFERVKDELREGRDIVRAVDRGWSRALRTICASDAVNFLAAIVLFLVAVGSVKGFAFTLGLT
TLVDLLVVVFFTHPVLQYLSHSSFFTRKYSGLNVKSAVYRGRLMTRDKSQKTIAERKAGH

Sequences:

>Translated_540_residues
MVVLLLLSLDIWQVFFSGSTFLPKLALDLEGGTQIVLRAKAAEKEITSEQLQQAVAIIRNRVDSSGISEAEISVQGSTNI
SVSIPGTPSQEVYDRIRSSSKMDMRAVLLTKPIQHAAMNEGSTHAGSTASAAIGDKNATRGSPKSSEHRKNIPKTPHDTS
GMIPSPRPKNGSDMAWITKYWRDRFDSHNCKDNAGDSTPDNLPLVVCDQYGTTKYLLGPVEVSGTDISRAVADPVSSHFA
GASIGWGVTITFNAHGGEKFKDVSNRLISLAAPRNQFAAVLDGVVITAPEVRGVTSNPQITGNFNQTTATALASQLSFGS
LPVSFEVQSSENISATLGSSQLQSGILAGILGMILVVVYSLFQYRLLGLLTVSSLICSAIVTYLVITFLSWQNGYRLSLA
GVAGLIVAIGITADSFIVYFERVKDELREGRDIVRAVDRGWSRALRTICASDAVNFLAAIVLFLVAVGSVKGFAFTLGLT
TLVDLLVVVFFTHPVLQYLSHSSFFTRKYSGLNVKSAVYRGRLMTRDKSQKTIAERKAGH
>Mature_540_residues
MVVLLLLSLDIWQVFFSGSTFLPKLALDLEGGTQIVLRAKAAEKEITSEQLQQAVAIIRNRVDSSGISEAEISVQGSTNI
SVSIPGTPSQEVYDRIRSSSKMDMRAVLLTKPIQHAAMNEGSTHAGSTASAAIGDKNATRGSPKSSEHRKNIPKTPHDTS
GMIPSPRPKNGSDMAWITKYWRDRFDSHNCKDNAGDSTPDNLPLVVCDQYGTTKYLLGPVEVSGTDISRAVADPVSSHFA
GASIGWGVTITFNAHGGEKFKDVSNRLISLAAPRNQFAAVLDGVVITAPEVRGVTSNPQITGNFNQTTATALASQLSFGS
LPVSFEVQSSENISATLGSSQLQSGILAGILGMILVVVYSLFQYRLLGLLTVSSLICSAIVTYLVITFLSWQNGYRLSLA
GVAGLIVAIGITADSFIVYFERVKDELREGRDIVRAVDRGWSRALRTICASDAVNFLAAIVLFLVAVGSVKGFAFTLGLT
TLVDLLVVVFFTHPVLQYLSHSSFFTRKYSGLNVKSAVYRGRLMTRDKSQKTIAERKAGH

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=201, Percent_Identity=27.8606965174129, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 58141; Mature: 58141

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVLLLLSLDIWQVFFSGSTFLPKLALDLEGGTQIVLRAKAAEKEITSEQLQQAVAIIRN
CEEEEEHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
RVDSSGISEAEISVQGSTNISVSIPGTPSQEVYDRIRSSSKMDMRAVLLTKPIQHAAMNE
HCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHCCHHHHHCCC
GSTHAGSTASAAIGDKNATRGSPKSSEHRKNIPKTPHDTSGMIPSPRPKNGSDMAWITKY
CCCCCCCCCHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
WRDRFDSHNCKDNAGDSTPDNLPLVVCDQYGTTKYLLGPVEVSGTDISRAVADPVSSHFA
HHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEECEEECCCCHHHHHHHHHHHHCC
GASIGWGVTITFNAHGGEKFKDVSNRLISLAAPRNQFAAVLDGVVITAPEVRGVTSNPQI
CCCCCCCEEEEEECCCCHHHHHHHHHHEECCCCHHHHHHHHCCEEEECCCCCCCCCCCEE
TGNFNQTTATALASQLSFGSLPVSFEVQSSENISATLGSSQLQSGILAGILGMILVVVYS
ECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
LFQYRLLGLLTVSSLICSAIVTYLVITFLSWQNGYRLSLAGVAGLIVAIGITADSFIVYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCHHHHHHHH
ERVKDELREGRDIVRAVDRGWSRALRTICASDAVNFLAAIVLFLVAVGSVKGFAFTLGLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TLVDLLVVVFFTHPVLQYLSHSSFFTRKYSGLNVKSAVYRGRLMTRDKSQKTIAERKAGH
HHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHCHHHCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MVVLLLLSLDIWQVFFSGSTFLPKLALDLEGGTQIVLRAKAAEKEITSEQLQQAVAIIRN
CEEEEEHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
RVDSSGISEAEISVQGSTNISVSIPGTPSQEVYDRIRSSSKMDMRAVLLTKPIQHAAMNE
HCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHCCHHHHHCCC
GSTHAGSTASAAIGDKNATRGSPKSSEHRKNIPKTPHDTSGMIPSPRPKNGSDMAWITKY
CCCCCCCCCHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
WRDRFDSHNCKDNAGDSTPDNLPLVVCDQYGTTKYLLGPVEVSGTDISRAVADPVSSHFA
HHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEECEEECCCCHHHHHHHHHHHHCC
GASIGWGVTITFNAHGGEKFKDVSNRLISLAAPRNQFAAVLDGVVITAPEVRGVTSNPQI
CCCCCCCEEEEEECCCCHHHHHHHHHHEECCCCHHHHHHHHCCEEEECCCCCCCCCCCEE
TGNFNQTTATALASQLSFGSLPVSFEVQSSENISATLGSSQLQSGILAGILGMILVVVYS
ECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
LFQYRLLGLLTVSSLICSAIVTYLVITFLSWQNGYRLSLAGVAGLIVAIGITADSFIVYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCHHHHHHHH
ERVKDELREGRDIVRAVDRGWSRALRTICASDAVNFLAAIVLFLVAVGSVKGFAFTLGLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TLVDLLVVVFFTHPVLQYLSHSSFFTRKYSGLNVKSAVYRGRLMTRDKSQKTIAERKAGH
HHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHCHHHCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]