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The map label for this gene is iap [H]

Identifier: 28572632

GI number: 28572632

Start: 520865

End: 521758

Strand: Reverse

Name: iap [H]

Synonym: TW483

Alternate gene names: 28572632

Gene position: 521758-520865 (Counterclockwise)

Preceding gene: 28572633

Following gene: 28572631

Centisome position: 56.35

GC content: 52.57

Gene sequence:

>894_bases
TTGGCCAGATTGCATTACCTCTTGATCCGCAAGGGCGTGTGTGTCTTGCACTTAAACCCGCTCCTCCCCACACATCCTTT
TGCAGCGCATATTCCGTTTTTCTTGTGTCAAGCTTGTTGCATTACGTGTTTTGTGTTACGGTCGTACTGTTTTGCGTGCA
GTCTTGCGCTTTCCAGATTTTTAGGAGGTTACTTGACAGCAGTTAGTATTCGGTCTTCTTTTCCCAGCAGGGATGATAGA
TATTCCAGGTATGTGCCAAGTGTGGGCGCAAGAAGGAGGGGGCTCTTGAGGCGCAGTGAGGGCCGGTCTGCCCCTATGGC
CTCTCTTGCCGTTGTTTTTATTTCTATTGCCGTCTCGACTGTTACAATGCCGGTTTATGCTGTCGATACGTATTCGGTTG
CTTCTAATCCTTATGAGGTGCAGGCCGTGCAGGTTGGTGGCGCTCATACACTGCCCGCACTCAATGGCGATGCTTATTCT
GTGGTGCGTCGTGGCGTTTCATCCTATCGTCCTGCTGTATTTGGCCTGAGTGCGGCACTAGTGCCCGTCCCATATACTCC
GTCGAGTGTGCTTGATGTTGCGTCAGAGTATGTTGGTGTTCCGTATAGATTTGGCGGCGCGGACCCCTCTTACGGTTTTG
ACTGTTCCGGACTTGTGAAGTATGTTTTTGCTCGCTTTGGCATAGCCCTCCCGCACTCTGTCTCTGGCCAAGCCGCCGCG
GGGAGAATTGTGCCGCGCTCGCAGGCAAGACCCGGAGATCTTGTTTTCATGCCGGGTCACAATGGTTTCTATGTTGGCCC
AGGCTTGATTCTCCACGCACCGGACTATGGCCGATCTGTCCGTGTGGCGCGGATCTGGACGGATAACTACTATATTGTCA
GAGTAGGTGGCTGA

Upstream 100 bases:

>100_bases
AGTCGGGGAGCTTTTAGTACCGCAACCGCTTGGCTGCATGTTCTGGGCTGTTATTGTGCTTGACCTTTTGGTTAAAGGTT
TATCTTTTGCGTGACCTGAC

Downstream 100 bases:

>100_bases
TTTGCCTCTGTAGCTCAATGGAAGAGCGGTTCCGTCCTAAGGAAATGGTTGGGGGTTCGAGTCCCTCCAGGGGCGCGTCG
TTTTCTGTTCAGTTACCTGG

Product: NLP/P60-family protein

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MARLHYLLIRKGVCVLHLNPLLPTHPFAAHIPFFLCQACCITCFVLRSYCFACSLALSRFLGGYLTAVSIRSSFPSRDDR
YSRYVPSVGARRRGLLRRSEGRSAPMASLAVVFISIAVSTVTMPVYAVDTYSVASNPYEVQAVQVGGAHTLPALNGDAYS
VVRRGVSSYRPAVFGLSAALVPVPYTPSSVLDVASEYVGVPYRFGGADPSYGFDCSGLVKYVFARFGIALPHSVSGQAAA
GRIVPRSQARPGDLVFMPGHNGFYVGPGLILHAPDYGRSVRVARIWTDNYYIVRVGG

Sequences:

>Translated_297_residues
MARLHYLLIRKGVCVLHLNPLLPTHPFAAHIPFFLCQACCITCFVLRSYCFACSLALSRFLGGYLTAVSIRSSFPSRDDR
YSRYVPSVGARRRGLLRRSEGRSAPMASLAVVFISIAVSTVTMPVYAVDTYSVASNPYEVQAVQVGGAHTLPALNGDAYS
VVRRGVSSYRPAVFGLSAALVPVPYTPSSVLDVASEYVGVPYRFGGADPSYGFDCSGLVKYVFARFGIALPHSVSGQAAA
GRIVPRSQARPGDLVFMPGHNGFYVGPGLILHAPDYGRSVRVARIWTDNYYIVRVGG
>Mature_296_residues
ARLHYLLIRKGVCVLHLNPLLPTHPFAAHIPFFLCQACCITCFVLRSYCFACSLALSRFLGGYLTAVSIRSSFPSRDDRY
SRYVPSVGARRRGLLRRSEGRSAPMASLAVVFISIAVSTVTMPVYAVDTYSVASNPYEVQAVQVGGAHTLPALNGDAYSV
VRRGVSSYRPAVFGLSAALVPVPYTPSSVLDVASEYVGVPYRFGGADPSYGFDCSGLVKYVFARFGIALPHSVSGQAAAG
RIVPRSQARPGDLVFMPGHNGFYVGPGLILHAPDYGRSVRVARIWTDNYYIVRVGG

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1788501, Length=93, Percent_Identity=40.8602150537634, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787944, Length=103, Percent_Identity=33.9805825242718, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 32097; Mature: 31966

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLHYLLIRKGVCVLHLNPLLPTHPFAAHIPFFLCQACCITCFVLRSYCFACSLALSRF
CCHHHEEHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGYLTAVSIRSSFPSRDDRYSRYVPSVGARRRGLLRRSEGRSAPMASLAVVFISIAVST
HHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
VTMPVYAVDTYSVASNPYEVQAVQVGGAHTLPALNGDAYSVVRRGVSSYRPAVFGLSAAL
HEEEEEEEEEEHHCCCCEEEEEEEECCCEECCCCCCHHHHHHHHHHHHCCCHHHCCCEEE
VPVPYTPSSVLDVASEYVGVPYRFGGADPSYGFDCSGLVKYVFARFGIALPHSVSGQAAA
EECCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
GRIVPRSQARPGDLVFMPGHNGFYVGPGLILHAPDYGRSVRVARIWTDNYYIVRVGG
CCCCCCCCCCCCCEEEECCCCCEEECCEEEEECCCCCCEEEEEEEEECCEEEEEECC
>Mature Secondary Structure 
ARLHYLLIRKGVCVLHLNPLLPTHPFAAHIPFFLCQACCITCFVLRSYCFACSLALSRF
CHHHEEHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGYLTAVSIRSSFPSRDDRYSRYVPSVGARRRGLLRRSEGRSAPMASLAVVFISIAVST
HHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
VTMPVYAVDTYSVASNPYEVQAVQVGGAHTLPALNGDAYSVVRRGVSSYRPAVFGLSAAL
HEEEEEEEEEEHHCCCCEEEEEEEECCCEECCCCCCHHHHHHHHHHHHCCCHHHCCCEEE
VPVPYTPSSVLDVASEYVGVPYRFGGADPSYGFDCSGLVKYVFARFGIALPHSVSGQAAA
EECCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
GRIVPRSQARPGDLVFMPGHNGFYVGPGLILHAPDYGRSVRVARIWTDNYYIVRVGG
CCCCCCCCCCCCCEEEECCCCCEEECCEEEEECCCCCCEEEEEEEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1514809; 1459966 [H]