Click here to switch to the map view.

The map label for this gene is coaE [H]

Identifier: 28572627

GI number: 28572627

Start: 515051

End: 515791

Strand: Reverse

Name: coaE [H]

Synonym: TW478

Alternate gene names: 28572627

Gene position: 515791-515051 (Counterclockwise)

Preceding gene: 28572628

Following gene: 28572626

Centisome position: 55.7

GC content: 45.61

Gene sequence:

>741_bases
TTGGTAATGCAGCTCTTCGCACTTACAGGCGGCATAGCTGCCGGTAAGTCTTGTGTTGCTGGCCTATTATCTGAATTTGG
TCTCCGTGTTGTCAGCGCGGATAGTTTGGTTGAGGTTCTTTACAGAACAGATGTGCGTCTTATTGAGGAGATAAAAGGAC
GTTTTCTCTGCAACGATGAGAAAAGTCTGTCTGAGCTTGTTTTCTCGGATTCGCGCGCGCGGAGGGTGCTAAATCAGCTT
ACCCACCAGAGAGTTAACCGCTTGGCATTAGATTATTTTTGGCAATTGCGTAATGAGCCGGTTGTGATTTATGAGATCCC
TATTCTCGAATCTACCTCTCCTTTTGTGGGCTTTGCGCCTGGGGAATGTGGAGTGTTTGCTTCCGGTAAAATTCAGCATT
CAGGTGTACTGTTTGTGCATTCAGATTGCGAGAGTCGCATTGACAGACTAATGAAACGTAATAACCTTAATCGTATCCAG
GCTTTGCAGAGGATTCATTCTCAGACCCCTTATATGCCACAATACTCACTGCGCGCTGGGGATTTACTGCGCACGGGGGA
TTTATCTCATGATTTTCGCGAGGAACGCGCCCCTCATAAGGGGGTAAAGGTTTATTCAGTGCACACTTCCGGAGTTTCAA
AAACGCTGTGCATGATACAGAATACATCTGATTTTTCTCATTTGAGGCAGTGTGTTGCCTCGGTCTTCCAAATTATGAAA
ACAATAGACCGAAGTGTATAA

Upstream 100 bases:

>100_bases
TGCACCCGAGACCTTGCCATCCGCTGAATCTGTATCTGCGATAGATTCAGATACAACAAACTCTCCAGAATCTGCAAAGG
GCAGTGAGCAAGACTAGTTA

Downstream 100 bases:

>100_bases
AAACTTACATCCAAAATATTTTAGGCTCGCTGCCGAATATGATCCATCTGGCGATCAACCGAAGGCGATTGGGGAGCTGT
CAGACAGAATAGAATCTGGT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MVMQLFALTGGIAAGKSCVAGLLSEFGLRVVSADSLVEVLYRTDVRLIEEIKGRFLCNDEKSLSELVFSDSRARRVLNQL
THQRVNRLALDYFWQLRNEPVVIYEIPILESTSPFVGFAPGECGVFASGKIQHSGVLFVHSDCESRIDRLMKRNNLNRIQ
ALQRIHSQTPYMPQYSLRAGDLLRTGDLSHDFREERAPHKGVKVYSVHTSGVSKTLCMIQNTSDFSHLRQCVASVFQIMK
TIDRSV

Sequences:

>Translated_246_residues
MVMQLFALTGGIAAGKSCVAGLLSEFGLRVVSADSLVEVLYRTDVRLIEEIKGRFLCNDEKSLSELVFSDSRARRVLNQL
THQRVNRLALDYFWQLRNEPVVIYEIPILESTSPFVGFAPGECGVFASGKIQHSGVLFVHSDCESRIDRLMKRNNLNRIQ
ALQRIHSQTPYMPQYSLRAGDLLRTGDLSHDFREERAPHKGVKVYSVHTSGVSKTLCMIQNTSDFSHLRQCVASVFQIMK
TIDRSV
>Mature_246_residues
MVMQLFALTGGIAAGKSCVAGLLSEFGLRVVSADSLVEVLYRTDVRLIEEIKGRFLCNDEKSLSELVFSDSRARRVLNQL
THQRVNRLALDYFWQLRNEPVVIYEIPILESTSPFVGFAPGECGVFASGKIQHSGVLFVHSDCESRIDRLMKRNNLNRIQ
ALQRIHSQTPYMPQYSLRAGDLLRTGDLSHDFREERAPHKGVKVYSVHTSGVSKTLCMIQNTSDFSHLRQCVASVFQIMK
TIDRSV

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=178, Percent_Identity=30.3370786516854, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI191252795, Length=178, Percent_Identity=30.3370786516854, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 27763; Mature: 27763

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMQLFALTGGIAAGKSCVAGLLSEFGLRVVSADSLVEVLYRTDVRLIEEIKGRFLCNDE
CCEEEEEHHCCHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHCCCEEECCH
KSLSELVFSDSRARRVLNQLTHQRVNRLALDYFWQLRNEPVVIYEIPILESTSPFVGFAP
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEECCCCCCEEECC
GECGVFASGKIQHSGVLFVHSDCESRIDRLMKRNNLNRIQALQRIHSQTPYMPQYSLRAG
CCCCEEECCCEECCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCC
DLLRTGDLSHDFREERAPHKGVKVYSVHTSGVSKTLCMIQNTSDFSHLRQCVASVFQIMK
CEEECCCCCHHHHHHCCCCCCCEEEEEECCCCHHHHHEEECCCCHHHHHHHHHHHHHHHH
TIDRSV
HHHCCC
>Mature Secondary Structure
MVMQLFALTGGIAAGKSCVAGLLSEFGLRVVSADSLVEVLYRTDVRLIEEIKGRFLCNDE
CCEEEEEHHCCHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHCCCEEECCH
KSLSELVFSDSRARRVLNQLTHQRVNRLALDYFWQLRNEPVVIYEIPILESTSPFVGFAP
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEECCCCCCEEECC
GECGVFASGKIQHSGVLFVHSDCESRIDRLMKRNNLNRIQALQRIHSQTPYMPQYSLRAG
CCCCEEECCCEECCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCC
DLLRTGDLSHDFREERAPHKGVKVYSVHTSGVSKTLCMIQNTSDFSHLRQCVASVFQIMK
CEEECCCCCHHHHHHCCCCCCCEEEEEECCCCHHHHHEEECCCCHHHHHHHHHHHHHHHH
TIDRSV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]