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The map label for this gene is yabD [H]

Identifier: 28572597

GI number: 28572597

Start: 486396

End: 487262

Strand: Direct

Name: yabD [H]

Synonym: TW446

Alternate gene names: 28572597

Gene position: 486396-487262 (Clockwise)

Preceding gene: 28572595

Following gene: 28572598

Centisome position: 52.53

GC content: 44.06

Gene sequence:

>867_bases
TTGCCGCTTACCCTACCCTCCCCGGTTTATGACTCTCATACCCATCTTGCGCCTGGCACAGATTACAAAGATCAATTAGA
CCGCGCTGAGGCGGTAAATGTAATTGGGGTTCTTCAGGTTGGCACTGATGTTAACACCAGCCATGCATCCGTGGAGCTTG
CAATGCAAGATCAGAGAATTCTTGCTGCTGTAGCAATTCATCCAAATGACGCTGCGGATATCTATAAAAAGGCAAATGAT
GCCACACACCGAGTTGAAGGCCAACCACACACAGAGTGTGAAAAATGCATACCCCCAGCAAAAGCTCTTGAAAAGAGTTT
GACACAGATCGCGAACCTCGCTGGTAGTAAAAGAGTGCGAGCAATTGGTGAAACTGGCCTGGATTATTTCCGCACACAGA
GTGATTTATATCGAGCAGCTCAGAGATTTAGCTTTGATGCGCATATACAAATTGCAAAAGAACATAATTTGGCACTTCAA
ATTCATGATCGAGATGCACATCGGGACGTTATTGAATGCTTGTTGCGTGCCGGTGCCCCTGATAGGACGATTTTTCATTG
CTTTTCCGGTGATGAACAGATGCTTGAAATTTGCATAAAGAACGGATGGTACATGTCATGCTCTGGAATCATTACCTTTA
AAAACGCGAGAGAAATGCAAAAAATATTTGCAAAAGTTCCAAAAGAATTGCTTCTGGTGGAAACAGATGCGCCATTTCTA
ACCCCCTCCCCTTTTAGGGGTTTCATGAATTCCTCCTATATGCTTGCCCATACCGTAAGGGCCCTGGCAGAAATAAGGCA
AGAGAATATCGATCAATTATGCACTCAACTTTCGCGTAATACATGCGAAATATTTGGTAAGTGGTAG

Upstream 100 bases:

>100_bases
CCCGTATAACCCAAAGGTACTGGCAAATAATGGCAAAACAAACACCTCAAAATGGAATAGAATACATGGGATGGCAGATA
AAGCATCAACATATCCCCCA

Downstream 100 bases:

>100_bases
CCTGCAAGGCCCACCATTATTTAATGGACCTCGCAATCAATCGTCCCGCATCCTATGGATATCGTGATGTATCTGTTTCT
GATCGCGGTAAAAAATATGC

Product: TatD-family DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MPLTLPSPVYDSHTHLAPGTDYKDQLDRAEAVNVIGVLQVGTDVNTSHASVELAMQDQRILAAVAIHPNDAADIYKKAND
ATHRVEGQPHTECEKCIPPAKALEKSLTQIANLAGSKRVRAIGETGLDYFRTQSDLYRAAQRFSFDAHIQIAKEHNLALQ
IHDRDAHRDVIECLLRAGAPDRTIFHCFSGDEQMLEICIKNGWYMSCSGIITFKNAREMQKIFAKVPKELLLVETDAPFL
TPSPFRGFMNSSYMLAHTVRALAEIRQENIDQLCTQLSRNTCEIFGKW

Sequences:

>Translated_288_residues
MPLTLPSPVYDSHTHLAPGTDYKDQLDRAEAVNVIGVLQVGTDVNTSHASVELAMQDQRILAAVAIHPNDAADIYKKAND
ATHRVEGQPHTECEKCIPPAKALEKSLTQIANLAGSKRVRAIGETGLDYFRTQSDLYRAAQRFSFDAHIQIAKEHNLALQ
IHDRDAHRDVIECLLRAGAPDRTIFHCFSGDEQMLEICIKNGWYMSCSGIITFKNAREMQKIFAKVPKELLLVETDAPFL
TPSPFRGFMNSSYMLAHTVRALAEIRQENIDQLCTQLSRNTCEIFGKW
>Mature_287_residues
PLTLPSPVYDSHTHLAPGTDYKDQLDRAEAVNVIGVLQVGTDVNTSHASVELAMQDQRILAAVAIHPNDAADIYKKANDA
THRVEGQPHTECEKCIPPAKALEKSLTQIANLAGSKRVRAIGETGLDYFRTQSDLYRAAQRFSFDAHIQIAKEHNLALQI
HDRDAHRDVIECLLRAGAPDRTIFHCFSGDEQMLEICIKNGWYMSCSGIITFKNAREMQKIFAKVPKELLLVETDAPFLT
PSPFRGFMNSSYMLAHTVRALAEIRQENIDQLCTQLSRNTCEIFGKW

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=175, Percent_Identity=29.7142857142857, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI110349730, Length=210, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI110349734, Length=210, Percent_Identity=25.7142857142857, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI226061853, Length=215, Percent_Identity=25.1162790697674, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787342, Length=283, Percent_Identity=29.6819787985866, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082439, Length=278, Percent_Identity=27.6978417266187, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI48994985, Length=277, Percent_Identity=27.0758122743682, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17559024, Length=227, Percent_Identity=26.8722466960352, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71980746, Length=168, Percent_Identity=30.952380952381, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565396, Length=193, Percent_Identity=28.4974093264249, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 32262; Mature: 32131

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTLPSPVYDSHTHLAPGTDYKDQLDRAEAVNVIGVLQVGTDVNTSHASVELAMQDQRI
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCCCCEEEEEECCCEE
LAAVAIHPNDAADIYKKANDATHRVEGQPHTECEKCIPPAKALEKSLTQIANLAGSKRVR
EEEEEECCCCHHHHHHHCCCCHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCHHHH
AIGETGLDYFRTQSDLYRAAQRFSFDAHIQIAKEHNLALQIHDRDAHRDVIECLLRAGAP
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCHHHHHHHHHHHHCCCC
DRTIFHCFSGDEQMLEICIKNGWYMSCSGIITFKNAREMQKIFAKVPKELLLVETDAPFL
CCEEEEEECCCHHHHHHHHHCCCEEEECCEEEECCHHHHHHHHHHCCHHEEEEECCCCCC
TPSPFRGFMNSSYMLAHTVRALAEIRQENIDQLCTQLSRNTCEIFGKW
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
>Mature Secondary Structure 
PLTLPSPVYDSHTHLAPGTDYKDQLDRAEAVNVIGVLQVGTDVNTSHASVELAMQDQRI
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCCCCEEEEEECCCEE
LAAVAIHPNDAADIYKKANDATHRVEGQPHTECEKCIPPAKALEKSLTQIANLAGSKRVR
EEEEEECCCCHHHHHHHCCCCHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCHHHH
AIGETGLDYFRTQSDLYRAAQRFSFDAHIQIAKEHNLALQIHDRDAHRDVIECLLRAGAP
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCHHHHHHHHHHHHCCCC
DRTIFHCFSGDEQMLEICIKNGWYMSCSGIITFKNAREMQKIFAKVPKELLLVETDAPFL
CCEEEEEECCCHHHHHHHHHCCCEEEECCEEEECCHHHHHHHHHHCCHHEEEEECCCCCC
TPSPFRGFMNSSYMLAHTVRALAEIRQENIDQLCTQLSRNTCEIFGKW
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]