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The map label for this gene is aroK [H]

Identifier: 28572551

GI number: 28572551

Start: 434582

End: 435082

Strand: Direct

Name: aroK [H]

Synonym: TW398

Alternate gene names: 28572551

Gene position: 434582-435082 (Clockwise)

Preceding gene: 28572550

Following gene: 28572552

Centisome position: 46.93

GC content: 43.71

Gene sequence:

>501_bases
ATGGCTATCGTACTAATTGGTCCTCCTGCCGTCGGGAAAACCCTTTTGGGGGGTCTTGTTGCAAAGCGCCTTCGGGTAAT
CTTTAACGATACAGATTTTCTAGTGGAAAAATTTTTTGGACCCGTGAAAGAACTGCTTTTAACCTGCGAAAGTCAGTTTA
GAGATGCTGAGTCCATCTGCTTGCGAAATGCCCTCTCTCGCGGGGGTGTTGTCGCAACTGGTGCAGGGTGTGTTCAGCGA
AAGGAAAATCAGAGGTACATATCCAGGCATTTAGTTATTTTTTTGCGCACCTCATGCGATAACGTCGCTCCACGCCTTTG
TTTTGACACACGTCCCGTAACGGGTGATATTGAATCATGGATTGCTGTGTACAACAAACGAAAAGATATTTATTCAAAAC
TGGCAGATATTGAATTTGATGTCAATAAGAGCAGTCCGATATCTTTAGCAGATCAACTTGTACGGTTTATTTACAATCGC
TCTTGGCATCGAGAATTCTGA

Upstream 100 bases:

>100_bases
AATAAAGCGGAATTTCTCTGGTTATCTTAACTCTATTCCAAAAAATCTCATGTCTGTCATAGAAAGATAGCTTCGGCCGT
AATCGGATTAATTGGAATCA

Downstream 100 bases:

>100_bases
TACCGTGCCTAGATTTTACTGTTGTCTTGCCGCAAGGTAGGTTGTAAAGGCGGAATCTTGTGATGAAGAAGTACTCGTTG
ACAACGCACAGCACGGAAAC

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MAIVLIGPPAVGKTLLGGLVAKRLRVIFNDTDFLVEKFFGPVKELLLTCESQFRDAESICLRNALSRGGVVATGAGCVQR
KENQRYISRHLVIFLRTSCDNVAPRLCFDTRPVTGDIESWIAVYNKRKDIYSKLADIEFDVNKSSPISLADQLVRFIYNR
SWHREF

Sequences:

>Translated_166_residues
MAIVLIGPPAVGKTLLGGLVAKRLRVIFNDTDFLVEKFFGPVKELLLTCESQFRDAESICLRNALSRGGVVATGAGCVQR
KENQRYISRHLVIFLRTSCDNVAPRLCFDTRPVTGDIESWIAVYNKRKDIYSKLADIEFDVNKSSPISLADQLVRFIYNR
SWHREF
>Mature_165_residues
AIVLIGPPAVGKTLLGGLVAKRLRVIFNDTDFLVEKFFGPVKELLLTCESQFRDAESICLRNALSRGGVVATGAGCVQRK
ENQRYISRHLVIFLRTSCDNVAPRLCFDTRPVTGDIESWIAVYNKRKDIYSKLADIEFDVNKSSPISLADQLVRFIYNRS
WHREF

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=164, Percent_Identity=29.8780487804878, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 18797; Mature: 18666

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVLIGPPAVGKTLLGGLVAKRLRVIFNDTDFLVEKFFGPVKELLLTCESQFRDAESIC
CEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LRNALSRGGVVATGAGCVQRKENQRYISRHLVIFLRTSCDNVAPRLCFDTRPVTGDIESW
HHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHCCCCCCCCCCHHHH
IAVYNKRKDIYSKLADIEFDVNKSSPISLADQLVRFIYNRSWHREF
HHHHHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AIVLIGPPAVGKTLLGGLVAKRLRVIFNDTDFLVEKFFGPVKELLLTCESQFRDAESIC
EEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LRNALSRGGVVATGAGCVQRKENQRYISRHLVIFLRTSCDNVAPRLCFDTRPVTGDIESW
HHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHCCCCCCCCCCHHHH
IAVYNKRKDIYSKLADIEFDVNKSSPISLADQLVRFIYNRSWHREF
HHHHHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA