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The map label for this gene is alr1 [H]

Identifier: 28572425

GI number: 28572425

Start: 299448

End: 300608

Strand: Reverse

Name: alr1 [H]

Synonym: TW266

Alternate gene names: 28572425

Gene position: 300608-299448 (Counterclockwise)

Preceding gene: 28572426

Following gene: 28572421

Centisome position: 32.47

GC content: 45.91

Gene sequence:

>1161_bases
ATGACACAAAGAACTGCTTTATCCAATTCCCACGCTCAAGCGTTTATTAGTCTCGGGACTTTGAAAAAGAATCTTCTGTG
GTTGCAAAATGAAGTCGCACCGGCAAAAGTTTTCATGGTTATAAAGGCAAATGCGAATGGACACGGGACGATGCGTGTTG
CCGAGGTGGCAAAAATGAGTGGAATTCGCAATTTTGCCGTTCTTCTCCCAAAAGAAGCCCTACTGATAAAACGAGCCTTA
TCGCCGGGAGTGCGAGTATTTACTTGGCATATTACCCCAGACTGTGAAGACCTGCCGAGCCTAATTGAGAACAATATTGA
AATTGGCATAGGTGCAGAATGGCAGTTGCGATATATCGCATCGTGTGTAAAAAAGACAATGACATGCGAGGTGCTGTCTG
GTTATAAACCAGCTCTAATTCATCTAAAGCTTGATACCGGCCTCAGTCGGGGTGGGTGTGGCGTGAAGGACTGGCAAAAT
CTTGTCTGTCTTGCACAAGACTTTCAGGAGATGGGCCTTATAAAGATAACTGGATTTTGGTCCCACCTGTCTAACACTTC
TCCAGAGGAAGATAGACGTTCCCTAAAGATATTCACGGAAAACGTCACGCCATATCTCGCAAGTTACAGCCGGCGTGCCA
GGCCAATAATGCATATCGCAGCGTCCGTTGCGGCATTGGGCCTGCCGGAGAGCAGGCTAGATTACGTAAGGCTAGGCCTC
TCATGTTTTGGTTATTACGAAAAAGAAGAACTAAAAGGCGTTATGACATTAGTTGCGCCAATTATAAAATTTCTTCCCGA
GCAGGGGCGTGCAATAATTGCATGTGGGTTTGCTGATGGAATCAGCCCGCTTGCGGTGCGCAATAATGTTCCTCTTACAG
GACGAAGTAACCGGGCAAGACTAATCGAGGTTGGGCCCGAAACATCTGTTATAGAGATCTGTCAAGATATCGATCGACGG
CAAGACAATTTGCAAAATAGTTATGATCACGTACCGCAAGACCCCTTTTTAAATGCACTGCGTGTCAGCCAAAACCATGT
TATTCTTTTCGGATCCGGAGGGCTTTCAGAGCTAACTGCCAGACAATGGGCAGAGTCTTGTGGGACAACAATAGATGATG
TCTTATCGCGTGTAAAAGCTGAGCTTATTTACCTGGAATAA

Upstream 100 bases:

>100_bases
TGCCTTACCGCAGGACTAGCATACAGGGTTGAGAAACGCTGGCTTACATAAAAAGATAAGGTCGGATGAAGAAAAGAAAC
GCAGATAACGAACAGACCAA

Downstream 100 bases:

>100_bases
ACTTGTATCTAATCGCGCGGGTAACCCTTTTTTTGATTACCCTCCGTGCCATGTGTGAATAAAAATCCAAGTCAGTTGCG
CTGGGTTGTGCGCAACAATA

Product: alanine racemase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTQRTALSNSHAQAFISLGTLKKNLLWLQNEVAPAKVFMVIKANANGHGTMRVAEVAKMSGIRNFAVLLPKEALLIKRAL
SPGVRVFTWHITPDCEDLPSLIENNIEIGIGAEWQLRYIASCVKKTMTCEVLSGYKPALIHLKLDTGLSRGGCGVKDWQN
LVCLAQDFQEMGLIKITGFWSHLSNTSPEEDRRSLKIFTENVTPYLASYSRRARPIMHIAASVAALGLPESRLDYVRLGL
SCFGYYEKEELKGVMTLVAPIIKFLPEQGRAIIACGFADGISPLAVRNNVPLTGRSNRARLIEVGPETSVIEICQDIDRR
QDNLQNSYDHVPQDPFLNALRVSQNHVILFGSGGLSELTARQWAESCGTTIDDVLSRVKAELIYLE

Sequences:

>Translated_386_residues
MTQRTALSNSHAQAFISLGTLKKNLLWLQNEVAPAKVFMVIKANANGHGTMRVAEVAKMSGIRNFAVLLPKEALLIKRAL
SPGVRVFTWHITPDCEDLPSLIENNIEIGIGAEWQLRYIASCVKKTMTCEVLSGYKPALIHLKLDTGLSRGGCGVKDWQN
LVCLAQDFQEMGLIKITGFWSHLSNTSPEEDRRSLKIFTENVTPYLASYSRRARPIMHIAASVAALGLPESRLDYVRLGL
SCFGYYEKEELKGVMTLVAPIIKFLPEQGRAIIACGFADGISPLAVRNNVPLTGRSNRARLIEVGPETSVIEICQDIDRR
QDNLQNSYDHVPQDPFLNALRVSQNHVILFGSGGLSELTARQWAESCGTTIDDVLSRVKAELIYLE
>Mature_385_residues
TQRTALSNSHAQAFISLGTLKKNLLWLQNEVAPAKVFMVIKANANGHGTMRVAEVAKMSGIRNFAVLLPKEALLIKRALS
PGVRVFTWHITPDCEDLPSLIENNIEIGIGAEWQLRYIASCVKKTMTCEVLSGYKPALIHLKLDTGLSRGGCGVKDWQNL
VCLAQDFQEMGLIKITGFWSHLSNTSPEEDRRSLKIFTENVTPYLASYSRRARPIMHIAASVAALGLPESRLDYVRLGLS
CFGYYEKEELKGVMTLVAPIIKFLPEQGRAIIACGFADGISPLAVRNNVPLTGRSNRARLIEVGPETSVIEICQDIDRRQ
DNLQNSYDHVPQDPFLNALRVSQNHVILFGSGGLSELTARQWAESCGTTIDDVLSRVKAELIYLE

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 42750; Mature: 42619

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRTALSNSHAQAFISLGTLKKNLLWLQNEVAPAKVFMVIKANANGHGTMRVAEVAKMS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHH
GIRNFAVLLPKEALLIKRALSPGVRVFTWHITPDCEDLPSLIENNIEIGIGAEWQLRYIA
CCCCEEEECCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCEEECCCCHHHHHHH
SCVKKTMTCEVLSGYKPALIHLKLDTGLSRGGCGVKDWQNLVCLAQDFQEMGLIKITGFW
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEH
SHLSNTSPEEDRRSLKIFTENVTPYLASYSRRARPIMHIAASVAALGLPESRLDYVRLGL
HHHCCCCCHHHHHEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHH
SCFGYYEKEELKGVMTLVAPIIKFLPEQGRAIIACGFADGISPLAVRNNVPLTGRSNRAR
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCCCCCCCCCE
LIEVGPETSVIEICQDIDRRQDNLQNSYDHVPQDPFLNALRVSQNHVILFGSGGLSELTA
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEECCCEEEEEECCCHHHHHH
RQWAESCGTTIDDVLSRVKAELIYLE
HHHHHHHCCCHHHHHHHHHHHEEEEC
>Mature Secondary Structure 
TQRTALSNSHAQAFISLGTLKKNLLWLQNEVAPAKVFMVIKANANGHGTMRVAEVAKMS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHH
GIRNFAVLLPKEALLIKRALSPGVRVFTWHITPDCEDLPSLIENNIEIGIGAEWQLRYIA
CCCCEEEECCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCEEECCCCHHHHHHH
SCVKKTMTCEVLSGYKPALIHLKLDTGLSRGGCGVKDWQNLVCLAQDFQEMGLIKITGFW
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEH
SHLSNTSPEEDRRSLKIFTENVTPYLASYSRRARPIMHIAASVAALGLPESRLDYVRLGL
HHHCCCCCHHHHHEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHH
SCFGYYEKEELKGVMTLVAPIIKFLPEQGRAIIACGFADGISPLAVRNNVPLTGRSNRAR
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCCCCCCCCCCE
LIEVGPETSVIEICQDIDRRQDNLQNSYDHVPQDPFLNALRVSQNHVILFGSGGLSELTA
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEECCCEEEEEECCCHHHHHH
RQWAESCGTTIDDVLSRVKAELIYLE
HHHHHHHCCCHHHHHHHHHHHEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]