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The map label for this gene is alr2 [H]

Identifier: 28572426

GI number: 28572426

Start: 300658

End: 301320

Strand: Reverse

Name: alr2 [H]

Synonym: TW267

Alternate gene names: 28572426

Gene position: 301320-300658 (Counterclockwise)

Preceding gene: 28572429

Following gene: 28572425

Centisome position: 32.54

GC content: 46.46

Gene sequence:

>663_bases
ATGATATCGCGTTTAGCAACTATTACATTGGAGAGTATAAAGAATAATGCCCTTCTGTGCCTGGAGGCCGATGGTGATAT
AACGGTCGATCTGCGTGCCGACGCATTTGGGCACGGGCTTGTGAAAATTGCTTACACCTTGTACAGCACAGGGGTCAGAA
AGTGTTTCGTGCGCAAAGCCCACGAAAAGATCTTTCTTGAAGAAATTGGGTTCACAGTGGATGTATCAGATGCGCCTATA
AAGCCATTCTCACACGATATATACGGCCTGGGTGATAATACAGAGTGCAAAGCTGCTTTGCATCTTGAAAGCTGCGTAGT
AACGTGCAAGAAACTGCCGGCAGGAGCGGGTGTAAGTTATTGTCACACATACAGAACACAGTCAGAGGAAAATGTTGCAC
TCATAGGCATAGGATATGCAGACGGACTGCCCTTTCAGGCTCAAGGATCTGTTGAAATAAAAAAGAGAAAATACCCCATT
ATCGGAAGAATAGCCATGGACTACATGGTTGCGAAGGTTACACCTGACTCGTATAAACATGGAACAAGAGTTACCGTATG
GGGAGAAAGCGGTGCAAAGACTTGGGGTTTGTCAGCGGGAATAGACCCCCTCTGCCTTACCGCAGGACTAGCATACAGGG
TTGAGAAACGCTGGCTTACATAA

Upstream 100 bases:

>100_bases
AGTAGGGCAATGTCATCGGCGTTATAATCAGTATTACTCGACAAGATAGCTCCTGAAATCTTCTAAAAGTCAGTATCAAA
CAAGTGTTTTGTGTCAAAGT

Downstream 100 bases:

>100_bases
AAAGATAAGGTCGGATGAAGAAAAGAAACGCAGATAACGAACAGACCAAATGACACAAAGAACTGCTTTATCCAATTCCC
ACGCTCAAGCGTTTATTAGT

Product: alanine racemase II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MISRLATITLESIKNNALLCLEADGDITVDLRADAFGHGLVKIAYTLYSTGVRKCFVRKAHEKIFLEEIGFTVDVSDAPI
KPFSHDIYGLGDNTECKAALHLESCVVTCKKLPAGAGVSYCHTYRTQSEENVALIGIGYADGLPFQAQGSVEIKKRKYPI
IGRIAMDYMVAKVTPDSYKHGTRVTVWGESGAKTWGLSAGIDPLCLTAGLAYRVEKRWLT

Sequences:

>Translated_220_residues
MISRLATITLESIKNNALLCLEADGDITVDLRADAFGHGLVKIAYTLYSTGVRKCFVRKAHEKIFLEEIGFTVDVSDAPI
KPFSHDIYGLGDNTECKAALHLESCVVTCKKLPAGAGVSYCHTYRTQSEENVALIGIGYADGLPFQAQGSVEIKKRKYPI
IGRIAMDYMVAKVTPDSYKHGTRVTVWGESGAKTWGLSAGIDPLCLTAGLAYRVEKRWLT
>Mature_220_residues
MISRLATITLESIKNNALLCLEADGDITVDLRADAFGHGLVKIAYTLYSTGVRKCFVRKAHEKIFLEEIGFTVDVSDAPI
KPFSHDIYGLGDNTECKAALHLESCVVTCKKLPAGAGVSYCHTYRTQSEENVALIGIGYADGLPFQAQGSVEIKKRKYPI
IGRIAMDYMVAKVTPDSYKHGTRVTVWGESGAKTWGLSAGIDPLCLTAGLAYRVEKRWLT

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 24050; Mature: 24050

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRLATITLESIKNNALLCLEADGDITVDLRADAFGHGLVKIAYTLYSTGVRKCFVRKA
CCCCEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
HEKIFLEEIGFTVDVSDAPIKPFSHDIYGLGDNTECKAALHLESCVVTCKKLPAGAGVSY
HHHHHHHHCCCEEECCCCCCCCCCCCEEECCCCCCEEEEEEHHHHHHHHHHCCCCCCCHH
CHTYRTQSEENVALIGIGYADGLPFQAQGSVEIKKRKYPIIGRIAMDYMVAKVTPDSYKH
HEEECCCCCCCEEEEEEECCCCCCEECCCCEEEEECCCCEEEHHHHHEEEEEECCCCCCC
GTRVTVWGESGAKTWGLSAGIDPLCLTAGLAYRVEKRWLT
CCEEEEECCCCCCCCCCCCCCCHHHHHHHHHEEEHHHCCC
>Mature Secondary Structure
MISRLATITLESIKNNALLCLEADGDITVDLRADAFGHGLVKIAYTLYSTGVRKCFVRKA
CCCCEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
HEKIFLEEIGFTVDVSDAPIKPFSHDIYGLGDNTECKAALHLESCVVTCKKLPAGAGVSY
HHHHHHHHCCCEEECCCCCCCCCCCCEEECCCCCCEEEEEEHHHHHHHHHHCCCCCCCHH
CHTYRTQSEENVALIGIGYADGLPFQAQGSVEIKKRKYPIIGRIAMDYMVAKVTPDSYKH
HEEECCCCCCCEEEEEEECCCCCCEECCCCEEEEECCCCEEEHHHHHEEEEEECCCCCCC
GTRVTVWGESGAKTWGLSAGIDPLCLTAGLAYRVEKRWLT
CCEEEEECCCCCCCCCCCCCCCHHHHHHHHHEEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]