Click here to switch to the map view.

The map label for this gene is infA

Identifier: 28572388

GI number: 28572388

Start: 255844

End: 256065

Strand: Direct

Name: infA

Synonym: TW228

Alternate gene names: 28572388

Gene position: 255844-256065 (Clockwise)

Preceding gene: 28572387

Following gene: 28572389

Centisome position: 27.63

GC content: 50.45

Gene sequence:

>222_bases
GTGGCGAAAAAGGATGGGGTGATCGAACTTGAGGGCTCCGTGCTTGAGGCGCTTCCCAACGCCACTTTTAGGGTTGAGTT
GAGTAATGGGCACAAAGTCCTGGCTCATATTTCTGGAAGGATGCGGCAGCACTATATAAGGATTCTTCCAGAGGACAGGG
TTGTTGTTGAGCTTAGTCCGTATGATCTGGCCAGGGGTCGTATTGTGTATCGCTACAAGTAG

Upstream 100 bases:

>100_bases
AAACGAGTTACTGGCTCGGTCAGCTGTTTAATTTGCTCTTGAGTCGCTTTTCGCGTAGAATTTCTACCCGGCGTTTTGTT
TTTTGCGTTAGGTCGGTGGT

Downstream 100 bases:

>100_bases
GGGTGCTTGTGAAGGTAAAGCCTAGCGTAAAGAAGATTTGTGGGGTCTGTAAGGTAATTCGCAGGAATGGTCGCGTTGCT
GTTTTGTGTTCGAATCCCAG

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 73; Mature: 72

Protein sequence:

>73_residues
MAKKDGVIELEGSVLEALPNATFRVELSNGHKVLAHISGRMRQHYIRILPEDRVVVELSPYDLARGRIVYRYK

Sequences:

>Translated_73_residues
MAKKDGVIELEGSVLEALPNATFRVELSNGHKVLAHISGRMRQHYIRILPEDRVVVELSPYDLARGRIVYRYK
>Mature_72_residues
AKKDGVIELEGSVLEALPNATFRVELSNGHKVLAHISGRMRQHYIRILPEDRVVVELSPYDLARGRIVYRYK

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=73, Percent_Identity=65.7534246575342, Blast_Score=103, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF1_TROW8 (Q83I58)

Other databases:

- EMBL:   BX251410
- RefSeq:   NP_789168.1
- ProteinModelPortal:   Q83I58
- SMR:   Q83I58
- STRING:   Q83I58
- GeneID:   1064520
- GenomeReviews:   BX072543_GR
- KEGG:   tws:TW228
- eggNOG:   COG0361
- HOGENOM:   HBG286099
- OMA:   KMRMHFI
- PhylomeDB:   Q83I58
- ProtClustDB:   PRK00276
- BioCyc:   TWHI218496:TW0213-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 8376; Mature: 8245

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKDGVIELEGSVLEALPNATFRVELSNGHKVLAHISGRMRQHYIRILPEDRVVVELSP
CCCCCCEEEECCCHHHHCCCCEEEEEECCCCEEEEEHHHHHHEEEEEECCCCCEEEEECC
YDLARGRIVYRYK
CCCCCCEEEEEEC
>Mature Secondary Structure 
AKKDGVIELEGSVLEALPNATFRVELSNGHKVLAHISGRMRQHYIRILPEDRVVVELSP
CCCCCEEEECCCHHHHCCCCEEEEEECCCCEEEEEHHHHHHEEEEEECCCCCEEEEECC
YDLARGRIVYRYK
CCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12606174