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The map label for this gene is ilvE [H]

Identifier: 28572387

GI number: 28572387

Start: 254911

End: 255774

Strand: Direct

Name: ilvE [H]

Synonym: TW227

Alternate gene names: 28572387

Gene position: 254911-255774 (Clockwise)

Preceding gene: 28572386

Following gene: 28572388

Centisome position: 27.53

GC content: 47.22

Gene sequence:

>864_bases
GTGAATACCGAGTATTTGCACGTTTTGTGGTTTAACCCCGATACTGATTGTGAGCCCCGTTTTTATGACGTGCATCACCC
GCTCATTCCTGCCACATCGGATGCAATAAATCGTGGTGTTGGTGTATTTGAAACAATTGGAATTCTATCGGGCAGGATAC
TGAATTTAGATGAACATCTTGAGAGAATGTGCACCTCCGCTAATCGCTTGGGCCTGAGGTCTATTGAACCGGATAGATGG
AGGAGCCTAATCTTACAATCTGCAAAAAAAATTGCTGATCAAGAGCGAGCTGGACTCAGGGTTGTGTATGCCAGGAATAG
CAATCGGTCTTATTTGGCATGGATAGCAGCTTTTGCTGTACGTGACCCAGATGCGCTTAGCAAAGGTATAAAAGTAATAA
CTCTTCAACGGGGTGTGCGGTCCGATGCAGGTCGACTGTATCCCTGGCTTCTTTTTGGTGCAAAAACTGTTTCCTATGCG
GTAAACATGCATGCACTCGAGGTGGCACAGGCGCGCGGTGCGGATGATGCAATTTTCCTCAGTGAAGATGGACTTGTACT
TGAGGGAACAACATCCAATCTTATTGCCTACAACAAGGGCGCTTTTATAACCCCATGCCCTCGGACAATGAGTATTCTCC
CCGGCACAACACAGAAGAGGCTGTTTATGCTTTTGGAAGCCGAGGGTAAAAAAACACTTGAGACTTCTGTCGCCACTGAG
GCATTGTACAATTCCGAGGGTGTATGGCTTACTTCAAGTGTGAGAATGATTACCCCGGTGGTTTCTGTGGATGGAAACCG
TGTGCGCTTTGACCCGGGTTTGACCGATTGGCTAAACGAGTTACTGGCTCGGTCAGCTGTTTAA

Upstream 100 bases:

>100_bases
GCGAAGAAAAGGGACTGCTTCACAGGATAGATGCTTCCAAGGGTATAGAGGAAGTTTTTCAGTCCATCAAAGATGTATTT
GACAGGGTGACAATTTAAAA

Downstream 100 bases:

>100_bases
TTTGCTCTTGAGTCGCTTTTCGCGTAGAATTTCTACCCGGCGTTTTGTTTTTTGCGTTAGGTCGGTGGTGTGGCGAAAAA
GGATGGGGTGATCGAACTTG

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MNTEYLHVLWFNPDTDCEPRFYDVHHPLIPATSDAINRGVGVFETIGILSGRILNLDEHLERMCTSANRLGLRSIEPDRW
RSLILQSAKKIADQERAGLRVVYARNSNRSYLAWIAAFAVRDPDALSKGIKVITLQRGVRSDAGRLYPWLLFGAKTVSYA
VNMHALEVAQARGADDAIFLSEDGLVLEGTTSNLIAYNKGAFITPCPRTMSILPGTTQKRLFMLLEAEGKKTLETSVATE
ALYNSEGVWLTSSVRMITPVVSVDGNRVRFDPGLTDWLNELLARSAV

Sequences:

>Translated_287_residues
MNTEYLHVLWFNPDTDCEPRFYDVHHPLIPATSDAINRGVGVFETIGILSGRILNLDEHLERMCTSANRLGLRSIEPDRW
RSLILQSAKKIADQERAGLRVVYARNSNRSYLAWIAAFAVRDPDALSKGIKVITLQRGVRSDAGRLYPWLLFGAKTVSYA
VNMHALEVAQARGADDAIFLSEDGLVLEGTTSNLIAYNKGAFITPCPRTMSILPGTTQKRLFMLLEAEGKKTLETSVATE
ALYNSEGVWLTSSVRMITPVVSVDGNRVRFDPGLTDWLNELLARSAV
>Mature_287_residues
MNTEYLHVLWFNPDTDCEPRFYDVHHPLIPATSDAINRGVGVFETIGILSGRILNLDEHLERMCTSANRLGLRSIEPDRW
RSLILQSAKKIADQERAGLRVVYARNSNRSYLAWIAAFAVRDPDALSKGIKVITLQRGVRSDAGRLYPWLLFGAKTVSYA
VNMHALEVAQARGADDAIFLSEDGLVLEGTTSNLIAYNKGAFITPCPRTMSILPGTTQKRLFMLLEAEGKKTLETSVATE
ALYNSEGVWLTSSVRMITPVVSVDGNRVRFDPGLTDWLNELLARSAV

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 31896; Mature: 31896

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTEYLHVLWFNPDTDCEPRFYDVHHPLIPATSDAINRGVGVFETIGILSGRILNLDEHL
CCCCEEEEEEECCCCCCCCCEEECCCCCCCCCHHHHHCCCCHHHHHHHHCCEEECHHHHH
ERMCTSANRLGLRSIEPDRWRSLILQSAKKIADQERAGLRVVYARNSNRSYLAWIAAFAV
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHC
RDPDALSKGIKVITLQRGVRSDAGRLYPWLLFGAKTVSYAVNMHALEVAQARGADDAIFL
CCHHHHHCCCEEEEEECCCCCCCCCCCHHEEECHHHHHHHHHHHHHHHHHHCCCCCEEEE
SEDGLVLEGTTSNLIAYNKGAFITPCPRTMSILPGTTQKRLFMLLEAEGKKTLETSVATE
ECCCEEEECCCCCEEEECCCCEECCCCCCCEECCCCCHHEEEEEEECCCCHHHHHHHHHH
ALYNSEGVWLTSSVRMITPVVSVDGNRVRFDPGLTDWLNELLARSAV
HHCCCCCEEEECCCEEEEEEEECCCCEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTEYLHVLWFNPDTDCEPRFYDVHHPLIPATSDAINRGVGVFETIGILSGRILNLDEHL
CCCCEEEEEEECCCCCCCCCEEECCCCCCCCCHHHHHCCCCHHHHHHHHCCEEECHHHHH
ERMCTSANRLGLRSIEPDRWRSLILQSAKKIADQERAGLRVVYARNSNRSYLAWIAAFAV
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHC
RDPDALSKGIKVITLQRGVRSDAGRLYPWLLFGAKTVSYAVNMHALEVAQARGADDAIFL
CCHHHHHCCCEEEEEECCCCCCCCCCCHHEEECHHHHHHHHHHHHHHHHHHCCCCCEEEE
SEDGLVLEGTTSNLIAYNKGAFITPCPRTMSILPGTTQKRLFMLLEAEGKKTLETSVATE
ECCCEEEECCCCCEEEECCCCEECCCCCCCEECCCCCHHEEEEEEECCCCHHHHHHHHHH
ALYNSEGVWLTSSVRMITPVVSVDGNRVRFDPGLTDWLNELLARSAV
HHCCCCCEEEECCCEEEEEEEECCCCEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]