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The map label for this gene is dppB [C]

Identifier: 28572312

GI number: 28572312

Start: 163138

End: 164073

Strand: Direct

Name: dppB [C]

Synonym: TW149

Alternate gene names: 28572312

Gene position: 163138-164073 (Clockwise)

Preceding gene: 28572309

Following gene: 28572313

Centisome position: 17.62

GC content: 46.05

Gene sequence:

>936_bases
TTGGGGCGCTATGTCTTGTTCCGGCTCCTGCAGTTTGTTCCGGTGTTCGTTGGTGCGACATTCCTGATTTATCTTCTTGT
ATTTCTCATGCCTGGGGATCCCATTGCTGCACTTTTCGGCGATAAAAGGCCGTCGCCTGATGTTGTTGCGGCAATTCGTG
AGCAGTACAACCTTGATAAACCGTTCATTGTCCAATATTTCATTTGGTTTTCTGGCATACTCACGGGCAATATGGGTGTT
ACATTTTCTGGCCAGAGTGTAACCGAGGTTCTGGGCAGTACAATTCCAGTCAGTGCGCAACTTGGGTTTATGGCCCTTGT
TATACAACTTCTTCTGGGTCTTTCGGTTGGCCTAATAGCTGGGCTGCGGCCGTATAGATTATTTGACACAACGAGCACTC
TGTTCTTACTTGCCCTTGTTTCAATACCATCTTTTGTGCTCGCATTTTTGCTTCAGTTTTTTATAGGAATTCAGCTTCGT
CTTCTGCCTGTAACGGTCGGTGGTGACACCAGCTTTTATCGAATGCTTCTGCCCGCATTCTCGCTCGGACTTCTCGGTAT
GGTTGGGTATGCCCGAGTTTTTAGGGGTGAAATCCTCAAAACCCGCGCACAAGATTTCGTTAATTTCGCTTACAGTAAAG
GTCTCTCCAAAGCCCGGGTTATTTTCGGTCATATAGTCCGCAATAGCCTCCTAGTTGTTGTGACTCTAATTGGTTTTGAT
TTGGCAGGTCTAATCGGCGGTGCGATTATAACTGAAGGCATATTCAATGTCCCAGGGGTTGGCAATGTGTTCTACCAGGC
GACAATTCGCGGAGAGGGTCCAACGATTGTTTCGTTTTCTGCAGTTTTTGTAATTGCCTTTATGCTTGCGAATCTCTTGG
TTGATATCAGTTATTCCTACATCGACCCGAGAATAAGGCTGTCTGGAAGAAAATAA

Upstream 100 bases:

>100_bases
ATGGTACAATGCAGGAAACGCGTTTAGAGCCTCGTAGCTGTGTGGCCCGCGCGGTTTTTTTGTTTCGCCGTTGAGCTGTG
TGAAACCGTGGAGGTGTGTT

Downstream 100 bases:

>100_bases
AGTGAGCAATAATAAATCCCTTGATGGCTATGCCAATCCGGTCGAGCATTATGTTGCCCCGTTTGACGAGGATGATTTTT
CCGCACCCCCGGATACATCT

Product: ABC transporter integral membrane subunit

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MGRYVLFRLLQFVPVFVGATFLIYLLVFLMPGDPIAALFGDKRPSPDVVAAIREQYNLDKPFIVQYFIWFSGILTGNMGV
TFSGQSVTEVLGSTIPVSAQLGFMALVIQLLLGLSVGLIAGLRPYRLFDTTSTLFLLALVSIPSFVLAFLLQFFIGIQLR
LLPVTVGGDTSFYRMLLPAFSLGLLGMVGYARVFRGEILKTRAQDFVNFAYSKGLSKARVIFGHIVRNSLLVVVTLIGFD
LAGLIGGAIITEGIFNVPGVGNVFYQATIRGEGPTIVSFSAVFVIAFMLANLLVDISYSYIDPRIRLSGRK

Sequences:

>Translated_311_residues
MGRYVLFRLLQFVPVFVGATFLIYLLVFLMPGDPIAALFGDKRPSPDVVAAIREQYNLDKPFIVQYFIWFSGILTGNMGV
TFSGQSVTEVLGSTIPVSAQLGFMALVIQLLLGLSVGLIAGLRPYRLFDTTSTLFLLALVSIPSFVLAFLLQFFIGIQLR
LLPVTVGGDTSFYRMLLPAFSLGLLGMVGYARVFRGEILKTRAQDFVNFAYSKGLSKARVIFGHIVRNSLLVVVTLIGFD
LAGLIGGAIITEGIFNVPGVGNVFYQATIRGEGPTIVSFSAVFVIAFMLANLLVDISYSYIDPRIRLSGRK
>Mature_310_residues
GRYVLFRLLQFVPVFVGATFLIYLLVFLMPGDPIAALFGDKRPSPDVVAAIREQYNLDKPFIVQYFIWFSGILTGNMGVT
FSGQSVTEVLGSTIPVSAQLGFMALVIQLLLGLSVGLIAGLRPYRLFDTTSTLFLLALVSIPSFVLAFLLQFFIGIQLRL
LPVTVGGDTSFYRMLLPAFSLGLLGMVGYARVFRGEILKTRAQDFVNFAYSKGLSKARVIFGHIVRNSLLVVVTLIGFDL
AGLIGGAIITEGIFNVPGVGNVFYQATIRGEGPTIVSFSAVFVIAFMLANLLVDISYSYIDPRIRLSGRK

Specific function: Probably part of the binding-protein-dependent transport system y4tOPQRS for a peptide. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=30.0595238095238, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789888, Length=309, Percent_Identity=33.3333333333333, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1787053, Length=307, Percent_Identity=31.2703583061889, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787497, Length=308, Percent_Identity=31.1688311688312, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787761, Length=334, Percent_Identity=29.0419161676647, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1788504, Length=366, Percent_Identity=25.1366120218579, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=25, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33979; Mature: 33848

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRYVLFRLLQFVPVFVGATFLIYLLVFLMPGDPIAALFGDKRPSPDVVAAIREQYNLDK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCC
PFIVQYFIWFSGILTGNMGVTFSGQSVTEVLGSTIPVSAQLGFMALVIQLLLGLSVGLIA
HHHHHHHHHHHHHHCCCCCEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLRPYRLFDTTSTLFLLALVSIPSFVLAFLLQFFIGIQLRLLPVTVGGDTSFYRMLLPAF
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCHHHHHHHHHHH
SLGLLGMVGYARVFRGEILKTRAQDFVNFAYSKGLSKARVIFGHIVRNSLLVVVTLIGFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAGLIGGAIITEGIFNVPGVGNVFYQATIRGEGPTIVSFSAVFVIAFMLANLLVDISYSY
HHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
IDPRIRLSGRK
CCCEEEECCCC
>Mature Secondary Structure 
GRYVLFRLLQFVPVFVGATFLIYLLVFLMPGDPIAALFGDKRPSPDVVAAIREQYNLDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCC
PFIVQYFIWFSGILTGNMGVTFSGQSVTEVLGSTIPVSAQLGFMALVIQLLLGLSVGLIA
HHHHHHHHHHHHHHCCCCCEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLRPYRLFDTTSTLFLLALVSIPSFVLAFLLQFFIGIQLRLLPVTVGGDTSFYRMLLPAF
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCHHHHHHHHHHH
SLGLLGMVGYARVFRGEILKTRAQDFVNFAYSKGLSKARVIFGHIVRNSLLVVVTLIGFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAGLIGGAIITEGIFNVPGVGNVFYQATIRGEGPTIVSFSAVFVIAFMLANLLVDISYSY
HHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHH
IDPRIRLSGRK
CCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9163424; 8796346 [H]