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The map label for this gene is appC [H]

Identifier: 28572313

GI number: 28572313

Start: 164075

End: 165040

Strand: Direct

Name: appC [H]

Synonym: TW150

Alternate gene names: 28572313

Gene position: 164075-165040 (Clockwise)

Preceding gene: 28572312

Following gene: 28572314

Centisome position: 17.72

GC content: 46.69

Gene sequence:

>966_bases
GTGAGCAATAATAAATCCCTTGATGGCTATGCCAATCCGGTCGAGCATTATGTTGCCCCGTTTGACGAGGATGATTTTTC
CGCACCCCCGGATACATCTGTTGGCAGACGTGCTTCCAAACTGCGCGATATATGGGTTTATCTCAGGCGCAGGTTTGCAT
TCTGGTTTTCTGTAGTTGTGCTTTTTACCCTCACCCTTGCTGCTCTTTTTCCGGGGCTATTTACACGTGTTCCGCCGAAC
AGCGATTGTTATTTGAAAAATTCGAACGGCGGACCAACAGGCGAGCATATTCTCGGGTTTACAAAACAGGGGTGCGATGT
CTTTTCTCGCATAGTGCATGGCGCCTCGACATCCCTATCGGTTGGGCTACTTACCCTTGCATTTGCTTTGGCAATAGGGG
TTACGATCGGTGCCCTCGCTGGATTTTTCGGTGGCTGGGTTGATGCAATTATTTCGAGGGCTGCTGATATATTCTTCGTT
ATTCCGTTTCTTGTTGCTGCAATCGTTGTTATGAGTGCGTTTTCGTCATTCCGTAGTGTTTTTACAATTGCACTTGTTCT
TGCAGTCTTCGGCTGGCCCGGGACAGCGCGTTTGGTAAGAAGTGAGGTTTATAGAGTAAAAAACCTTGAGTTTGTTTTGG
CCGCTCATTGCTTGGGTCAAAGAAAATGGGGTATTTTGATGAAACATATAATCCCGAATTCCCTAAGCCCTATCTATTCC
CTTGCCGCTATCAGTGTTGGTTATGCCATTATCTCCGAGACTGTGCTTTCTTTTCTTGGCCTTGGTCTTCCATCAAATGT
GATGAGTTGGGGTAATGATATAGCGTCTGCACAGCCTGATTTACGCAATAACCCCATGACTCTTTTCTGGCCCTCTTTGG
TCCTGTCCGTCACGGTACTTGCCTTTACACTTCTTGGCGATGTAATACGCAAAGCCAATAATCCAGCTGAAAGATCCAAG
GGATGA

Upstream 100 bases:

>100_bases
TCTGCAGTTTTTGTAATTGCCTTTATGCTTGCGAATCTCTTGGTTGATATCAGTTATTCCTACATCGACCCGAGAATAAG
GCTGTCTGGAAGAAAATAAA

Downstream 100 bases:

>100_bases
ATACGGTTGAGCCCCCACTTCTGGATGTTAGAAATCTACAGATCGAATTTTCTACACCTACCCGCGCAATAAAGGCCGTT
GATGGCGTCAGTTTTACCCT

Product: ABC transporter system integral membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSNNKSLDGYANPVEHYVAPFDEDDFSAPPDTSVGRRASKLRDIWVYLRRRFAFWFSVVVLFTLTLAALFPGLFTRVPPN
SDCYLKNSNGGPTGEHILGFTKQGCDVFSRIVHGASTSLSVGLLTLAFALAIGVTIGALAGFFGGWVDAIISRAADIFFV
IPFLVAAIVVMSAFSSFRSVFTIALVLAVFGWPGTARLVRSEVYRVKNLEFVLAAHCLGQRKWGILMKHIIPNSLSPIYS
LAAISVGYAIISETVLSFLGLGLPSNVMSWGNDIASAQPDLRNNPMTLFWPSLVLSVTVLAFTLLGDVIRKANNPAERSK
G

Sequences:

>Translated_321_residues
MSNNKSLDGYANPVEHYVAPFDEDDFSAPPDTSVGRRASKLRDIWVYLRRRFAFWFSVVVLFTLTLAALFPGLFTRVPPN
SDCYLKNSNGGPTGEHILGFTKQGCDVFSRIVHGASTSLSVGLLTLAFALAIGVTIGALAGFFGGWVDAIISRAADIFFV
IPFLVAAIVVMSAFSSFRSVFTIALVLAVFGWPGTARLVRSEVYRVKNLEFVLAAHCLGQRKWGILMKHIIPNSLSPIYS
LAAISVGYAIISETVLSFLGLGLPSNVMSWGNDIASAQPDLRNNPMTLFWPSLVLSVTVLAFTLLGDVIRKANNPAERSK
G
>Mature_320_residues
SNNKSLDGYANPVEHYVAPFDEDDFSAPPDTSVGRRASKLRDIWVYLRRRFAFWFSVVVLFTLTLAALFPGLFTRVPPNS
DCYLKNSNGGPTGEHILGFTKQGCDVFSRIVHGASTSLSVGLLTLAFALAIGVTIGALAGFFGGWVDAIISRAADIFFVI
PFLVAAIVVMSAFSSFRSVFTIALVLAVFGWPGTARLVRSEVYRVKNLEFVLAAHCLGQRKWGILMKHIIPNSLSPIYSL
AAISVGYAIISETVLSFLGLGLPSNVMSWGNDIASAQPDLRNNPMTLFWPSLVLSVTVLAFTLLGDVIRKANNPAERSKG

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=276, Percent_Identity=32.9710144927536, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1787760, Length=304, Percent_Identity=29.6052631578947, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789889, Length=224, Percent_Identity=31.6964285714286, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787498, Length=282, Percent_Identity=31.2056737588652, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789964, Length=229, Percent_Identity=34.061135371179, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788505, Length=228, Percent_Identity=28.0701754385965, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787549, Length=217, Percent_Identity=29.4930875576037, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34842; Mature: 34711

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNKSLDGYANPVEHYVAPFDEDDFSAPPDTSVGRRASKLRDIWVYLRRRFAFWFSVVV
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFTLTLAALFPGLFTRVPPNSDCYLKNSNGGPTGEHILGFTKQGCDVFSRIVHGASTSLS
HHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
VGLLTLAFALAIGVTIGALAGFFGGWVDAIISRAADIFFVIPFLVAAIVVMSAFSSFRSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTIALVLAVFGWPGTARLVRSEVYRVKNLEFVLAAHCLGQRKWGILMKHIIPNSLSPIYS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHH
LAAISVGYAIISETVLSFLGLGLPSNVMSWGNDIASAQPDLRNNPMTLFWPSLVLSVTVL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHCCCCCCCCCCCEEEHHHHHHHHHHH
AFTLLGDVIRKANNPAERSKG
HHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SNNKSLDGYANPVEHYVAPFDEDDFSAPPDTSVGRRASKLRDIWVYLRRRFAFWFSVVV
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]