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The map label for this gene is xerD [H]

Identifier: 28572274

GI number: 28572274

Start: 107600

End: 108649

Strand: Reverse

Name: xerD [H]

Synonym: TW108

Alternate gene names: 28572274

Gene position: 108649-107600 (Counterclockwise)

Preceding gene: 28572275

Following gene: 28572268

Centisome position: 11.73

GC content: 47.9

Gene sequence:

>1050_bases
GTGTCTAAAAATACTGTGACCAAGGTCGCAGACATAGCAATACCCCCGGATATAAAACCCGATTTTGATTGGTTTTTTCC
CTTTGCAAAACTGGAGCTAGGACTATCGGATGCAACCCTCCAAACATATCGCAATTCACTGGGAATCTATCTATCCTGGC
TTGGCGAGCAGGGCACCCAACGCTTGAGTGAAGTCAATTCAAATGCAATCGAAAGATTTTTAGAGTATAGACAGCGCCAT
ACGCGAAAAAGCACCCTCGCAAATACCGTTGCTGCGTTACGCACTTTTCACAGGCATTTAGTGTTAGAAGGCCGACAAGC
TCTAAATCCCACAGAGAAATTACAACAGCCAAAAGTGCCGAAGGCCCTCCCGCATCCTTTGAGCCTTGATGAGATAATAA
ACCTTCTCAAGGCAGCAGATGCAAATCAAGCGCGGGAAATATCATTGCGTGACAGGGCACTGATCGAGGTATTGTACGGA
ACAGGTGCAAGGATCAGCGAAGCGGTTAGCCTAAATGTTAATGCCTTTGCCGAAAGTGATCAAAATCTCCTACGACTTAC
AGGAAAAGGTAACAAACAGCGCATGGTCCTATTTGGGTCGTATGCACGGAATGCCGTGGATAATTACCTGCAACATTCTA
GGCCAAAGCTGTTAGCGAGGTCCCATGTTTATCGTAATATAACGGATGCTAGTACATTGAAATATAGGCCCACAAGTTCG
ACAATTGGGGATGCTGAGGACGGAGTGCTGACAGCAACCGCGGCTGGCGTGCCATGGCTATTTCTCAGCAACCGCGGAAA
ACGTCTAACCAGGCAACAGGCTGGAAATATAATCCGCAAGCTCGGCGAAGCTGCTGAGATTGGCAGATACATATCACCAC
ATTCACTGCGGCATTCTTTCGCAACCCACATGCTACAGGCTGGGGCAGATATAAGAACCGTTCAGGAATTGCTCGGGCAC
AGCTCGATAAATACGACCAGTGTATACACAAAGGTCACGATCGACAGCCTACGGGAGGTGTACACCACGTCGCATCCACG
GGCTTTATAA

Upstream 100 bases:

>100_bases
ATTACCTATATATTTGTTGACGGGCCCGGTTACTTTGGTTACCCAATTGTTTATTGTGGTTAGCCCTGTTTTGGTTGAGT
TTAGGAATTTGAGGTGAGCT

Downstream 100 bases:

>100_bases
ATGAGCACGAGATAAATCATCGCGTAATATTGTGTGCCGTTCATACGGTGTTTCGTGCGTTTGCAGTATGGATCAAGCGG
GGTTGATTTGTTAGCCCCGG

Product: DNA recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSKNTVTKVADIAIPPDIKPDFDWFFPFAKLELGLSDATLQTYRNSLGIYLSWLGEQGTQRLSEVNSNAIERFLEYRQRH
TRKSTLANTVAALRTFHRHLVLEGRQALNPTEKLQQPKVPKALPHPLSLDEIINLLKAADANQAREISLRDRALIEVLYG
TGARISEAVSLNVNAFAESDQNLLRLTGKGNKQRMVLFGSYARNAVDNYLQHSRPKLLARSHVYRNITDASTLKYRPTSS
TIGDAEDGVLTATAAGVPWLFLSNRGKRLTRQQAGNIIRKLGEAAEIGRYISPHSLRHSFATHMLQAGADIRTVQELLGH
SSINTTSVYTKVTIDSLREVYTTSHPRAL

Sequences:

>Translated_349_residues
MSKNTVTKVADIAIPPDIKPDFDWFFPFAKLELGLSDATLQTYRNSLGIYLSWLGEQGTQRLSEVNSNAIERFLEYRQRH
TRKSTLANTVAALRTFHRHLVLEGRQALNPTEKLQQPKVPKALPHPLSLDEIINLLKAADANQAREISLRDRALIEVLYG
TGARISEAVSLNVNAFAESDQNLLRLTGKGNKQRMVLFGSYARNAVDNYLQHSRPKLLARSHVYRNITDASTLKYRPTSS
TIGDAEDGVLTATAAGVPWLFLSNRGKRLTRQQAGNIIRKLGEAAEIGRYISPHSLRHSFATHMLQAGADIRTVQELLGH
SSINTTSVYTKVTIDSLREVYTTSHPRAL
>Mature_348_residues
SKNTVTKVADIAIPPDIKPDFDWFFPFAKLELGLSDATLQTYRNSLGIYLSWLGEQGTQRLSEVNSNAIERFLEYRQRHT
RKSTLANTVAALRTFHRHLVLEGRQALNPTEKLQQPKVPKALPHPLSLDEIINLLKAADANQAREISLRDRALIEVLYGT
GARISEAVSLNVNAFAESDQNLLRLTGKGNKQRMVLFGSYARNAVDNYLQHSRPKLLARSHVYRNITDASTLKYRPTSST
IGDAEDGVLTATAAGVPWLFLSNRGKRLTRQQAGNIIRKLGEAAEIGRYISPHSLRHSFATHMLQAGADIRTVQELLGHS
SINTTSVYTKVTIDSLREVYTTSHPRAL

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=326, Percent_Identity=35.2760736196319, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1790244, Length=333, Percent_Identity=30.3303303303303, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1790768, Length=71, Percent_Identity=45.0704225352113, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 38965; Mature: 38834

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNTVTKVADIAIPPDIKPDFDWFFPFAKLELGLSDATLQTYRNSLGIYLSWLGEQGTQ
CCCCHHHHHHHCCCCCCCCCCCHHHCCHHHHHCCCCHHHHHHHHHHHCEEEEHHCHHHHH
RLSEVNSNAIERFLEYRQRHTRKSTLANTVAALRTFHRHLVLEGRQALNPTEKLQQPKVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHCCCCCC
KALPHPLSLDEIINLLKAADANQAREISLRDRALIEVLYGTGARISEAVSLNVNAFAESD
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHEEECHHHHHCCC
QNLLRLTGKGNKQRMVLFGSYARNAVDNYLQHSRPKLLARSHVYRNITDASTLKYRPTSS
CCEEEEECCCCCEEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEECCCCC
TIGDAEDGVLTATAAGVPWLFLSNRGKRLTRQQAGNIIRKLGEAAEIGRYISPHSLRHSF
CCCCCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ATHMLQAGADIRTVQELLGHSSINTTSVYTKVTIDSLREVYTTSHPRAL
HHHHHHCCCHHHHHHHHHCCCCCCCCHHEEHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SKNTVTKVADIAIPPDIKPDFDWFFPFAKLELGLSDATLQTYRNSLGIYLSWLGEQGTQ
CCCHHHHHHHCCCCCCCCCCCHHHCCHHHHHCCCCHHHHHHHHHHHCEEEEHHCHHHHH
RLSEVNSNAIERFLEYRQRHTRKSTLANTVAALRTFHRHLVLEGRQALNPTEKLQQPKVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHCCCCCC
KALPHPLSLDEIINLLKAADANQAREISLRDRALIEVLYGTGARISEAVSLNVNAFAESD
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHEEECHHHHHCCC
QNLLRLTGKGNKQRMVLFGSYARNAVDNYLQHSRPKLLARSHVYRNITDASTLKYRPTSS
CCEEEEECCCCCEEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEECCCCC
TIGDAEDGVLTATAAGVPWLFLSNRGKRLTRQQAGNIIRKLGEAAEIGRYISPHSLRHSF
CCCCCCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ATHMLQAGADIRTVQELLGHSSINTTSVYTKVTIDSLREVYTTSHPRAL
HHHHHHCCCHHHHHHHHHCCCCCCCCHHEEHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]