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The map label for this gene is ecsA [H]

Identifier: 28572272

GI number: 28572272

Start: 104352

End: 105071

Strand: Direct

Name: ecsA [H]

Synonym: TW106

Alternate gene names: 28572272

Gene position: 104352-105071 (Clockwise)

Preceding gene: 28572271

Following gene: 28572273

Centisome position: 11.27

GC content: 44.86

Gene sequence:

>720_bases
ATGAATATTCTTTCCGTCCAAGATGTTTCGTTTTCATATGATAAATCCACACCAGCTATCTATGGCGTTGATCTTCAGAT
TGATCCCGGCGAGGTGGTTGGCCTGGTTGGCCCTAACGGGTCAGGTAAGTCAACATTTATAAAACTTGTTTTTGACCTCC
TTGAATTGCAAAAAGGGCAGATACAGATCCTGGGCAATAATCACCGTCTCACGACTGCCCGTCTTGCATCTATATACCTG
CCGAGCGATGATGACCTTCCAGAATTTCTAACCGGCGATGAATACCTGCGAACACTCTTTAGGCTCTATAAACGACCTTT
TGATAAAAACAGTGTATTGCGTGAATTTGACCGCTTCGGCATGCGAGGTCGTGAGCGTAATTTAATAGAGGATTATTCCC
ACGGCATGCGCAAAAAGCTACAGCTGATTAGTGCATTTCTGCTGCAACTTCCCCTGACTGTTATAGATGAGACAATAAAT
GGAATTGATCTTGATGCCGTGTATGAGTGTCGTAAATCCATTACGGAACTAAAGTCTCGCGGACACTCTGTTTTACTCTG
CACCCATGACTTTTATTTTTTGCAAAAAGTGGCCGATAAAGTCATCGTATTCCATCAGGCCAAACAAATTGCCAGCTTTG
CCACACCGTCACACGAACACCTGGAGGATCGCGTGGCAGAAATACTGGGAGTAGATCTGCATGATAGGGGAGCGCTGTGA

Upstream 100 bases:

>100_bases
CTGGCCAAATATTCCTTTTGATTCTCTTTACAGAGGCTATTGTTGCCATTCCCCTGACTATCCTTGCTGTTCAGGCGGTT
AGAAAAAGCGAGCGTTACGC

Downstream 100 bases:

>100_bases
CTCAGGCATTTAGCAGAAGGTCACCGTTTCGCAAAATAAAACTTGTCACGGCAATACTCTCATCCAGTTTTGCTCTATCA
ATGATTACCGTTTTTGTTTC

Product: ABC transport ATP-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MNILSVQDVSFSYDKSTPAIYGVDLQIDPGEVVGLVGPNGSGKSTFIKLVFDLLELQKGQIQILGNNHRLTTARLASIYL
PSDDDLPEFLTGDEYLRTLFRLYKRPFDKNSVLREFDRFGMRGRERNLIEDYSHGMRKKLQLISAFLLQLPLTVIDETIN
GIDLDAVYECRKSITELKSRGHSVLLCTHDFYFLQKVADKVIVFHQAKQIASFATPSHEHLEDRVAEILGVDLHDRGAL

Sequences:

>Translated_239_residues
MNILSVQDVSFSYDKSTPAIYGVDLQIDPGEVVGLVGPNGSGKSTFIKLVFDLLELQKGQIQILGNNHRLTTARLASIYL
PSDDDLPEFLTGDEYLRTLFRLYKRPFDKNSVLREFDRFGMRGRERNLIEDYSHGMRKKLQLISAFLLQLPLTVIDETIN
GIDLDAVYECRKSITELKSRGHSVLLCTHDFYFLQKVADKVIVFHQAKQIASFATPSHEHLEDRVAEILGVDLHDRGAL
>Mature_239_residues
MNILSVQDVSFSYDKSTPAIYGVDLQIDPGEVVGLVGPNGSGKSTFIKLVFDLLELQKGQIQILGNNHRLTTARLASIYL
PSDDDLPEFLTGDEYLRTLFRLYKRPFDKNSVLREFDRFGMRGRERNLIEDYSHGMRKKLQLISAFLLQLPLTVIDETIN
GIDLDAVYECRKSITELKSRGHSVLLCTHDFYFLQKVADKVIVFHQAKQIASFATPSHEHLEDRVAEILGVDLHDRGAL

Specific function: Has a role in exoprotein production, sporulation and competence [H]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27881506, Length=203, Percent_Identity=27.0935960591133, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI10947137, Length=203, Percent_Identity=27.0935960591133, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI150417984, Length=230, Percent_Identity=25.2173913043478, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI105990541, Length=207, Percent_Identity=25.1207729468599, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786319, Length=193, Percent_Identity=24.3523316062176, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789751, Length=203, Percent_Identity=29.5566502463054, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786872, Length=208, Percent_Identity=25, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87081782, Length=198, Percent_Identity=26.7676767676768, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787500, Length=209, Percent_Identity=23.444976076555, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788165, Length=221, Percent_Identity=26.2443438914027, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789593, Length=233, Percent_Identity=25.3218884120172, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI48995001, Length=206, Percent_Identity=27.6699029126214, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17555318, Length=203, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320874, Length=206, Percent_Identity=27.1844660194175, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666092, Length=234, Percent_Identity=27.3504273504274, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24641342, Length=201, Percent_Identity=29.8507462686567, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28573573, Length=177, Percent_Identity=31.0734463276836, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573571, Length=177, Percent_Identity=31.0734463276836, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24642252, Length=208, Percent_Identity=28.8461538461538, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI18859989, Length=208, Percent_Identity=28.8461538461538, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27111; Mature: 27111

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILSVQDVSFSYDKSTPAIYGVDLQIDPGEVVGLVGPNGSGKSTFIKLVFDLLELQKGQ
CCCCEECCCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCC
IQILGNNHRLTTARLASIYLPSDDDLPEFLTGDEYLRTLFRLYKRPFDKNSVLREFDRFG
EEEEECCCEEHHHHEEEEECCCCCCCHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHC
MRGRERNLIEDYSHGMRKKLQLISAFLLQLPLTVIDETINGIDLDAVYECRKSITELKSR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GHSVLLCTHDFYFLQKVADKVIVFHQAKQIASFATPSHEHLEDRVAEILGVDLHDRGAL
CCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNILSVQDVSFSYDKSTPAIYGVDLQIDPGEVVGLVGPNGSGKSTFIKLVFDLLELQKGQ
CCCCEECCCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCC
IQILGNNHRLTTARLASIYLPSDDDLPEFLTGDEYLRTLFRLYKRPFDKNSVLREFDRFG
EEEEECCCEEHHHHEEEEECCCCCCCHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHC
MRGRERNLIEDYSHGMRKKLQLISAFLLQLPLTVIDETINGIDLDAVYECRKSITELKSR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GHSVLLCTHDFYFLQKVADKVIVFHQAKQIASFATPSHEHLEDRVAEILGVDLHDRGAL
CCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8581172; 9579061; 9384377 [H]