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The map label for this gene is yaeL [C]

Identifier: 28572265

GI number: 28572265

Start: 97781

End: 98905

Strand: Direct

Name: yaeL [C]

Synonym: TW098

Alternate gene names: 28572265

Gene position: 97781-98905 (Clockwise)

Preceding gene: 28572263

Following gene: 28572267

Centisome position: 10.56

GC content: 43.91

Gene sequence:

>1125_bases
ATGTTTTTTCTTGGTGTCCTGATCATTCTTATTTTTGTGTATATTGCAGTTGCCCTGCATGAACTTGGACACATGCTACC
GGCAAAGTATTTCGGTGTGCCGGTGCAGAAATATGCAATTGGATTTGGACCATCTCTTTTCAGTTTTAAGAAGCGCGAGA
CTTCATATTCTTTCAATCTTCTACCATTGGGTGGGTATGTTCAGCTGGAGGGCATGCTGCCTCCATCTGAAAACCCTCGA
CGTTGGTTTAAAAAACTTATGAAATTTGCCGAATCTGATAGCCCACGGGCGTTTTGGCGCCTGCCTGCTTGGAAAAAAAT
AATAGTTATGTTTTCTGGTCCGTTTGTAAATCTTATTCTCGCGACATTGGGGTATGTATTCGTTCTATCTGTTCTGGGCC
TCCCGGTTATAAAACCGGTGATTCACGAGGTTATTGCGAACACTCCGGCTGCTTCTGCCGGAATTCTTCCGGGTGATGAA
ATTATTGCAATAAACGACACAGCAATCAGCTCACCGGGTCAGATTAGGGGTCTCATACAAGACAAGGATCTTGTTACGCT
ATCGCTTCTCAAAGATGGCGGCACCCGTATTGTTTCACTGCGACCTTTGAATGGTTCAATTGGTGTGAAGTTTTCGACGG
TGAATGAAAGGCAGTCAATTTTTGATGCTTTGTCAAGTATGGTAAAAGATACCGTTGGCGTGGCAAAATCTCTTATCGCT
CTGCCATATAACCTGTTTACGGGCCTTGCCGATACATTACATCAGAGAAAAGATGGTGTGGTTGGCCTTATTGGTGCGGC
TAGAATCTCGGGTGATATTGTATCCGCACCCAGCATTTCATTGTATGACAAGTTGCGGAGCATGATCTGGATTTTTGCCT
CATTGAATCTTGCGTTATTTGTTTTCAACATGATTCCTCTTTTACCTTTTGACGGTGGGTATATTGCTGCTGCTGTTTTT
GAGGGCGCGCGTTCACGCGTGCTTCTTGCGTTCAGAAAAAATGACTACGCTCCAGTCAATATCTCATATTTGTTACCTGT
TACACTGCTTGTAACAGCCGCGATTATTGTGATGAGTATTATGCTCGCCTGGATAGATATAGTAAACCCGCTTCGTCTTG
GTTAG

Upstream 100 bases:

>100_bases
TGCGTCATAGCGAACAGTATATACATCTCAGAACGTTCAACTTTACCTAACATAGGCCAAATGAGTCTGGTATCATTTCC
TCGATCAAGAAGGGGGTTTG

Downstream 100 bases:

>100_bases
CTCAGTCAGCGCTCATATTCTCTATAACTGTTTTGGCTAGCTCTCTGGTTCGGGCATCCTCTTCTAAAATGACCTCAATT
GGATTTTTCGCCGACTCGCG

Product: metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MFFLGVLIILIFVYIAVALHELGHMLPAKYFGVPVQKYAIGFGPSLFSFKKRETSYSFNLLPLGGYVQLEGMLPPSENPR
RWFKKLMKFAESDSPRAFWRLPAWKKIIVMFSGPFVNLILATLGYVFVLSVLGLPVIKPVIHEVIANTPAASAGILPGDE
IIAINDTAISSPGQIRGLIQDKDLVTLSLLKDGGTRIVSLRPLNGSIGVKFSTVNERQSIFDALSSMVKDTVGVAKSLIA
LPYNLFTGLADTLHQRKDGVVGLIGAARISGDIVSAPSISLYDKLRSMIWIFASLNLALFVFNMIPLLPFDGGYIAAAVF
EGARSRVLLAFRKNDYAPVNISYLLPVTLLVTAAIIVMSIMLAWIDIVNPLRLG

Sequences:

>Translated_374_residues
MFFLGVLIILIFVYIAVALHELGHMLPAKYFGVPVQKYAIGFGPSLFSFKKRETSYSFNLLPLGGYVQLEGMLPPSENPR
RWFKKLMKFAESDSPRAFWRLPAWKKIIVMFSGPFVNLILATLGYVFVLSVLGLPVIKPVIHEVIANTPAASAGILPGDE
IIAINDTAISSPGQIRGLIQDKDLVTLSLLKDGGTRIVSLRPLNGSIGVKFSTVNERQSIFDALSSMVKDTVGVAKSLIA
LPYNLFTGLADTLHQRKDGVVGLIGAARISGDIVSAPSISLYDKLRSMIWIFASLNLALFVFNMIPLLPFDGGYIAAAVF
EGARSRVLLAFRKNDYAPVNISYLLPVTLLVTAAIIVMSIMLAWIDIVNPLRLG
>Mature_374_residues
MFFLGVLIILIFVYIAVALHELGHMLPAKYFGVPVQKYAIGFGPSLFSFKKRETSYSFNLLPLGGYVQLEGMLPPSENPR
RWFKKLMKFAESDSPRAFWRLPAWKKIIVMFSGPFVNLILATLGYVFVLSVLGLPVIKPVIHEVIANTPAASAGILPGDE
IIAINDTAISSPGQIRGLIQDKDLVTLSLLKDGGTRIVSLRPLNGSIGVKFSTVNERQSIFDALSSMVKDTVGVAKSLIA
LPYNLFTGLADTLHQRKDGVVGLIGAARISGDIVSAPSISLYDKLRSMIWIFASLNLALFVFNMIPLLPFDGGYIAAAVF
EGARSRVLLAFRKNDYAPVNISYLLPVTLLVTAAIIVMSIMLAWIDIVNPLRLG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=191, Percent_Identity=30.8900523560209, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 40855; Mature: 40855

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFLGVLIILIFVYIAVALHELGHMLPAKYFGVPVQKYAIGFGPSLFSFKKRETSYSFNL
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHCCCCCHHHHHHHHCCCCEEEE
LPLGGYVQLEGMLPPSENPRRWFKKLMKFAESDSPRAFWRLPAWKKIIVMFSGPFVNLIL
EECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCHHHHHHH
ATLGYVFVLSVLGLPVIKPVIHEVIANTPAASAGILPGDEIIAINDTAISSPGQIRGLIQ
HHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEC
DKDLVTLSLLKDGGTRIVSLRPLNGSIGVKFSTVNERQSIFDALSSMVKDTVGVAKSLIA
CCCEEEEEEECCCCCEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
LPYNLFTGLADTLHQRKDGVVGLIGAARISGDIVSAPSISLYDKLRSMIWIFASLNLALF
HHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHH
VFNMIPLLPFDGGYIAAAVFEGARSRVLLAFRKNDYAPVNISYLLPVTLLVTAAIIVMSI
HHHHHHCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHH
MLAWIDIVNPLRLG
HHHHHHHHCHHCCC
>Mature Secondary Structure
MFFLGVLIILIFVYIAVALHELGHMLPAKYFGVPVQKYAIGFGPSLFSFKKRETSYSFNL
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHCCCCCHHHHHHHHCCCCEEEE
LPLGGYVQLEGMLPPSENPRRWFKKLMKFAESDSPRAFWRLPAWKKIIVMFSGPFVNLIL
EECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCHHHHHHH
ATLGYVFVLSVLGLPVIKPVIHEVIANTPAASAGILPGDEIIAINDTAISSPGQIRGLIQ
HHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEC
DKDLVTLSLLKDGGTRIVSLRPLNGSIGVKFSTVNERQSIFDALSSMVKDTVGVAKSLIA
CCCEEEEEEECCCCCEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
LPYNLFTGLADTLHQRKDGVVGLIGAARISGDIVSAPSISLYDKLRSMIWIFASLNLALF
HHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHH
VFNMIPLLPFDGGYIAAAVFEGARSRVLLAFRKNDYAPVNISYLLPVTLLVTAAIIVMSI
HHHHHHCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHH
MLAWIDIVNPLRLG
HHHHHHHHCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]