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The map label for this gene is groES [H]

Identifier: 28572252

GI number: 28572252

Start: 82958

End: 83341

Strand: Direct

Name: groES [H]

Synonym: TW084

Alternate gene names: 28572252

Gene position: 82958-83341 (Clockwise)

Preceding gene: 28572250

Following gene: 28572253

Centisome position: 8.96

GC content: 52.34

Gene sequence:

>384_bases
TTGTTACGCTTTGGTAGAATATTGTTCTCGCGGGGCTTTCTGCCTTCGATTGATTTGGAAGTCTTAGTACATGGAAGAGG
TTCAGCTGTGTCATTTGCAATTAAACCACTCGGCGATCGTGTAGTTATCAGACCGGCCGATGCGGAGCAGGTTACAGCAA
GCGGTTTGGTTATTCCCGATACCGCGCAGGAGCGCCCTCAGGAGGGTGAAGTTGTTGCCGTCGGTCCCGGTTCTCTTAAC
GACGATGGGAATCGTGTCCCGCTTGATGTTTCTGTCGGCGATCGCGTTATCTACGCGCGCTATGGTGGTACCGAGGTTAA
ACTGGGCGATGACGAGTACACGATCTTGGCTTCAAGGGATGTGCTCGCGGTTGTTCATCGGTAA

Upstream 100 bases:

>100_bases
GGGGGCGCTTGCGTCAAAGTTATTCACACATACATTATGTCATTGTTTGCATGCTGTTATCCCCCTCGCGTATGCGGGGT
GTTTTGCGTTTTAGCACTGC

Downstream 100 bases:

>100_bases
CCGACTCTTTTAGCCCGTTCCTCTTGCGTACCATTCGGTAGCGTGTTGTTGTGCACCCCCATAAGCTTTCCGGAGTTGGG
CTCACGTATGACGATGTTAT

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MLRFGRILFSRGFLPSIDLEVLVHGRGSAVSFAIKPLGDRVVIRPADAEQVTASGLVIPDTAQERPQEGEVVAVGPGSLN
DDGNRVPLDVSVGDRVIYARYGGTEVKLGDDEYTILASRDVLAVVHR

Sequences:

>Translated_127_residues
MLRFGRILFSRGFLPSIDLEVLVHGRGSAVSFAIKPLGDRVVIRPADAEQVTASGLVIPDTAQERPQEGEVVAVGPGSLN
DDGNRVPLDVSVGDRVIYARYGGTEVKLGDDEYTILASRDVLAVVHR
>Mature_127_residues
MLRFGRILFSRGFLPSIDLEVLVHGRGSAVSFAIKPLGDRVVIRPADAEQVTASGLVIPDTAQERPQEGEVVAVGPGSLN
DDGNRVPLDVSVGDRVIYARYGGTEVKLGDDEYTILASRDVLAVVHR

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=38.5416666666667, Blast_Score=69, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555568, Length=101, Percent_Identity=41.5841584158416, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324594, Length=96, Percent_Identity=41.6666666666667, Blast_Score=76, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356029, Length=93, Percent_Identity=41.9354838709677, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358317, Length=98, Percent_Identity=36.734693877551, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 13640; Mature: 13640

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFGRILFSRGFLPSIDLEVLVHGRGSAVSFAIKPLGDRVVIRPADAEQVTASGLVIPD
CCCCCCEEECCCCCCCCCEEEEEECCCCEEEEEEECCCCEEEEEECCCCCEEECCEEECC
TAQERPQEGEVVAVGPGSLNDDGNRVPLDVSVGDRVIYARYGGTEVKLGDDEYTILASRD
CHHCCCCCCCEEEECCCCCCCCCCEEEEEECCCCEEEEEEECCEEEEECCCCEEEEECCC
VLAVVHR
EEEEEEC
>Mature Secondary Structure
MLRFGRILFSRGFLPSIDLEVLVHGRGSAVSFAIKPLGDRVVIRPADAEQVTASGLVIPD
CCCCCCEEECCCCCCCCCEEEEEECCCCEEEEEEECCCCEEEEEECCCCCEEECCEEECC
TAQERPQEGEVVAVGPGSLNDDGNRVPLDVSVGDRVIYARYGGTEVKLGDDEYTILASRD
CHHCCCCCCCEEEECCCCCCCCCCEEEEEECCCCEEEEEEECCEEEEECCCCEEEEECCC
VLAVVHR
EEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA