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The map label for this gene is wbbL [H]

Identifier: 28572210

GI number: 28572210

Start: 33457

End: 34305

Strand: Reverse

Name: wbbL [H]

Synonym: TW037

Alternate gene names: 28572210

Gene position: 34305-33457 (Counterclockwise)

Preceding gene: 28572211

Following gene: 28572207

Centisome position: 3.7

GC content: 45.11

Gene sequence:

>849_bases
ATGACAATGATCGCTCGATTCGAGCTTATAACCGTAACATACAACTGCTCTGATATCTTGAGAGATTTTTTAGTATCAGT
CCAAGATTCGGAACCCAATCGAGTGAGTGTAACTGTTGTTGACAATAACTCACATGATAGAAGTATCTGCAAAGATTATG
CCCGACAGTTTGGTGCTAGGTTTATCGCACTAGAGAAAAACTCCGGATACGGCGCAGCGGTCAATGCGGGCGCCAAGAGG
CTGCCAAGCAATATAGAGTACATCGGGATTTGTAATCCTGATTTAGCGCTGGAGAAGGGAACTATTAGCACTCTCTTGAG
TGTTTTCGAACAGGATAAAGATGCTGTCGCTGCGGGCCCATGCATTCTAAATCAGGACGGTACTCCATATCCATCCGCAC
GTGATATTCCAGGCATTTCAAACGGGGTTGGTCATGCATTGTTTAAAAATATATGGCCGGACAATCCATGGACCCGCAGC
TATACCCAGAGCGCTCTCGGGACAAAAAGACGGACCTGCGGATGGCTCAGTGGGGCGTTCTTCATCATACGCAGAAATGC
ATTCGAAGATGTGGGCGGATTCGATGAGGGGTTTTTTATGTATTTCGAGGATGTCGACTTGTTTTCACGTCTACAGAAAA
GACCTCGCTACGAGCCAAATGCGAAAGTCAAGCATATAGGTAGATATTCAACTCGGCAAAACCCAAAAACAATGCTTTTT
TTTCACCACAAATCTGCGGGGCGCTTTCTTGACAAGAAATACTCAAAAAAATGGCAGAAACCCGTTACATTCCTTCTGAA
ACTTGGACTGAAACTCAGGTACCGTCTACAGGCAAGAAAACTGAAGTAG

Upstream 100 bases:

>100_bases
TAGAGACTGTATGCGATAAGGTCATGGTCTTGAAAAATGGAAGATTGATCTACTATGGCACAACAAAAGTCGGGCTGGAT
TTACTAAGAGAAAACTATCA

Downstream 100 bases:

>100_bases
TGAGTTTTTATGAAAACCCGTGCTTACCGCTCAGGAGGTAGTGCAAATACTTCCCATAACCACTTTTCATAAGCCCATTT
GCAAGTTTGGCCAGCTGATC

Product: glycosyl transferase

Products: NA

Alternate protein names: Rhamnosyltransferase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTMIARFELITVTYNCSDILRDFLVSVQDSEPNRVSVTVVDNNSHDRSICKDYARQFGARFIALEKNSGYGAAVNAGAKR
LPSNIEYIGICNPDLALEKGTISTLLSVFEQDKDAVAAGPCILNQDGTPYPSARDIPGISNGVGHALFKNIWPDNPWTRS
YTQSALGTKRRTCGWLSGAFFIIRRNAFEDVGGFDEGFFMYFEDVDLFSRLQKRPRYEPNAKVKHIGRYSTRQNPKTMLF
FHHKSAGRFLDKKYSKKWQKPVTFLLKLGLKLRYRLQARKLK

Sequences:

>Translated_282_residues
MTMIARFELITVTYNCSDILRDFLVSVQDSEPNRVSVTVVDNNSHDRSICKDYARQFGARFIALEKNSGYGAAVNAGAKR
LPSNIEYIGICNPDLALEKGTISTLLSVFEQDKDAVAAGPCILNQDGTPYPSARDIPGISNGVGHALFKNIWPDNPWTRS
YTQSALGTKRRTCGWLSGAFFIIRRNAFEDVGGFDEGFFMYFEDVDLFSRLQKRPRYEPNAKVKHIGRYSTRQNPKTMLF
FHHKSAGRFLDKKYSKKWQKPVTFLLKLGLKLRYRLQARKLK
>Mature_281_residues
TMIARFELITVTYNCSDILRDFLVSVQDSEPNRVSVTVVDNNSHDRSICKDYARQFGARFIALEKNSGYGAAVNAGAKRL
PSNIEYIGICNPDLALEKGTISTLLSVFEQDKDAVAAGPCILNQDGTPYPSARDIPGISNGVGHALFKNIWPDNPWTRSY
TQSALGTKRRTCGWLSGAFFIIRRNAFEDVGGFDEGFFMYFEDVDLFSRLQKRPRYEPNAKVKHIGRYSTRQNPKTMLFF
HHKSAGRFLDKKYSKKWQKPVTFLLKLGLKLRYRLQARKLK

Specific function: Involved in the biosynthesis of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the transfer of the rhamnosyl moiety from dTDP-rhamnosyl (dTDP-Rha) onto the undecaprenyl-pyrophosphoryl

COG id: COG1216

COG function: function code R; Predicted glycosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: NA

Molecular weight: Translated: 32082; Mature: 31951

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMIARFELITVTYNCSDILRDFLVSVQDSEPNRVSVTVVDNNSHDRSICKDYARQFGAR
CCEEEEEEEEEEEECHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCE
FIALEKNSGYGAAVNAGAKRLPSNIEYIGICNPDLALEKGTISTLLSVFEQDKDAVAAGP
EEEEECCCCCCCEECCCHHHCCCCCCEEEECCCCCEECCCHHHHHHHHHHCCCCCEECCC
CILNQDGTPYPSARDIPGISNGVGHALFKNIWPDNPWTRSYTQSALGTKRRTCGWLSGAF
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHCCEE
FIIRRNAFEDVGGFDEGFFMYFEDVDLFSRLQKRPRYEPNAKVKHIGRYSTRQNPKTMLF
EEEECCCHHHCCCCCCCEEEEEECHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCEEEE
FHHKSAGRFLDKKYSKKWQKPVTFLLKLGLKLRYRLQARKLK
EEECCCCHHHHHHHHHHHHHHHHHHHHHCHHHEEEHHHCCCC
>Mature Secondary Structure 
TMIARFELITVTYNCSDILRDFLVSVQDSEPNRVSVTVVDNNSHDRSICKDYARQFGAR
CEEEEEEEEEEEECHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCE
FIALEKNSGYGAAVNAGAKRLPSNIEYIGICNPDLALEKGTISTLLSVFEQDKDAVAAGP
EEEEECCCCCCCEECCCHHHCCCCCCEEEECCCCCEECCCHHHHHHHHHHCCCCCEECCC
CILNQDGTPYPSARDIPGISNGVGHALFKNIWPDNPWTRSYTQSALGTKRRTCGWLSGAF
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHCCEE
FIIRRNAFEDVGGFDEGFFMYFEDVDLFSRLQKRPRYEPNAKVKHIGRYSTRQNPKTMLF
EEEECCCHHHCCCCCCCEEEEEECHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCEEEE
FHHKSAGRFLDKKYSKKWQKPVTFLLKLGLKLRYRLQARKLK
EEECCCCHHHHHHHHHHHHHHHHHHHHHCHHHEEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]