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The map label for this gene is rfbB [H]

Identifier: 28572211

GI number: 28572211

Start: 34302

End: 35108

Strand: Reverse

Name: rfbB [H]

Synonym: TW038

Alternate gene names: 28572211

Gene position: 35108-34302 (Counterclockwise)

Preceding gene: 28572212

Following gene: 28572210

Centisome position: 3.79

GC content: 42.26

Gene sequence:

>807_bases
ATGAAAAATAAGATGTCAGTGGTAAATAGTAATGCGGTAAAACTGGCGAAGTCGAAGCACTATACCGGTGTGACAAATGA
CAATGCGATACTGCGAGTCAGTAATGTATCGAAAAAATTTGTAATACAGCATAATAGGTCAATCAAAGAGAGACTGCTTA
ATTTCAGGGTTTCCCGGGCAAACAGAGAGCCGTTTTGGGCTCTAAAAAATATAACCTTTGAGTTGCCAATTGGTAGCTCC
GTTGGTCTTGTGGGGCACAATGGCTCCGGGAAGTCAACTCTTCTGAAGCTAATAGGTGGCATAGTAAGGGCAACAGAAGG
TGAAATACTGAGCCGCGGGCGGATAAGCGCCCTCATTGAACTGGGTGCCGGATTTCACCCCGATCTCACCGGAAGAGAGA
ATATATACCTGAACGGGTCAATCTTGGGGCTAACAAAAGCAGAAATAAGACGGAATTTTGACTCAATTGTTGACTTTTCG
GGGATAGAAAAATTCATTGATACACAGGTCAAATTTTATAGCTCAGGTATGTATATGCGACTTGCGTTTTCTGTGTCTGT
ACATACAGACCCAGACCTTTTGTTGATTGATGAGATTCTTGCTGTCGGCGATGCGCCATTTCAAAAAAAGTGTCTCAATA
AGGTTACCCAGTTCAAAAATGAAGGGCGAAGCATTGTTATGGTAAGCCATGTAGCCGAACAGATAGAGACTGTATGCGAT
AAGGTCATGGTCTTGAAAAATGGAAGATTGATCTACTATGGCACAACAAAAGTCGGGCTGGATTTACTAAGAGAAAACTA
TCAATGA

Upstream 100 bases:

>100_bases
CCACAGGATTTTTGTTAAGATGCAGGCGAACTTGGCGCAAGAGCTGTGAATGTCAGGCAAGAGATAAGTCCCAAGCGGTT
TTATTGCAGATAAACTCACA

Downstream 100 bases:

>100_bases
CAATGATCGCTCGATTCGAGCTTATAACCGTAACATACAACTGCTCTGATATCTTGAGAGATTTTTTAGTATCAGTCCAA
GATTCGGAACCCAATCGAGT

Product: ABC transport ATP-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MKNKMSVVNSNAVKLAKSKHYTGVTNDNAILRVSNVSKKFVIQHNRSIKERLLNFRVSRANREPFWALKNITFELPIGSS
VGLVGHNGSGKSTLLKLIGGIVRATEGEILSRGRISALIELGAGFHPDLTGRENIYLNGSILGLTKAEIRRNFDSIVDFS
GIEKFIDTQVKFYSSGMYMRLAFSVSVHTDPDLLLIDEILAVGDAPFQKKCLNKVTQFKNEGRSIVMVSHVAEQIETVCD
KVMVLKNGRLIYYGTTKVGLDLLRENYQ

Sequences:

>Translated_268_residues
MKNKMSVVNSNAVKLAKSKHYTGVTNDNAILRVSNVSKKFVIQHNRSIKERLLNFRVSRANREPFWALKNITFELPIGSS
VGLVGHNGSGKSTLLKLIGGIVRATEGEILSRGRISALIELGAGFHPDLTGRENIYLNGSILGLTKAEIRRNFDSIVDFS
GIEKFIDTQVKFYSSGMYMRLAFSVSVHTDPDLLLIDEILAVGDAPFQKKCLNKVTQFKNEGRSIVMVSHVAEQIETVCD
KVMVLKNGRLIYYGTTKVGLDLLRENYQ
>Mature_268_residues
MKNKMSVVNSNAVKLAKSKHYTGVTNDNAILRVSNVSKKFVIQHNRSIKERLLNFRVSRANREPFWALKNITFELPIGSS
VGLVGHNGSGKSTLLKLIGGIVRATEGEILSRGRISALIELGAGFHPDLTGRENIYLNGSILGLTKAEIRRNFDSIVDFS
GIEKFIDTQVKFYSSGMYMRLAFSVSVHTDPDLLLIDEILAVGDAPFQKKCLNKVTQFKNEGRSIVMVSHVAEQIETVCD
KVMVLKNGRLIYYGTTKVGLDLLRENYQ

Specific function: May form an ATP-driven O-antigen export apparatus, in association with RfbA [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI6005701, Length=212, Percent_Identity=30.6603773584906, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI27477115, Length=212, Percent_Identity=29.7169811320755, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI150417984, Length=213, Percent_Identity=27.2300469483568, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI27436953, Length=211, Percent_Identity=29.8578199052133, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI153792144, Length=255, Percent_Identity=26.6666666666667, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI27262624, Length=241, Percent_Identity=26.5560165975104, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI27262626, Length=241, Percent_Identity=26.5560165975104, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI31657092, Length=206, Percent_Identity=26.6990291262136, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI105990541, Length=192, Percent_Identity=27.6041666666667, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI21536376, Length=213, Percent_Identity=26.2910798122066, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI27881501, Length=204, Percent_Identity=25, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI30795238, Length=204, Percent_Identity=25, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI47078218, Length=192, Percent_Identity=27.0833333333333, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI45446740, Length=192, Percent_Identity=27.0833333333333, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI116734710, Length=213, Percent_Identity=24.4131455399061, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI87081709, Length=209, Percent_Identity=25.8373205741627, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786398, Length=242, Percent_Identity=24.7933884297521, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790467, Length=197, Percent_Identity=27.4111675126904, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786345, Length=206, Percent_Identity=29.126213592233, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081782, Length=193, Percent_Identity=26.4248704663212, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787370, Length=191, Percent_Identity=26.1780104712042, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994943, Length=206, Percent_Identity=23.7864077669903, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081791, Length=203, Percent_Identity=25.1231527093596, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788761, Length=196, Percent_Identity=27.5510204081633, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789962, Length=258, Percent_Identity=25.5813953488372, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788210, Length=205, Percent_Identity=26.3414634146341, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789032, Length=207, Percent_Identity=22.2222222222222, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87082267, Length=199, Percent_Identity=24.6231155778894, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788897, Length=206, Percent_Identity=25.7281553398058, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48995001, Length=201, Percent_Identity=24.8756218905473, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786319, Length=199, Percent_Identity=24.6231155778894, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789873, Length=212, Percent_Identity=29.2452830188679, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787029, Length=210, Percent_Identity=25.2380952380952, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=202, Percent_Identity=24.7524752475248, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533608, Length=208, Percent_Identity=24.5192307692308, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71983523, Length=216, Percent_Identity=26.8518518518519, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71983516, Length=216, Percent_Identity=26.8518518518519, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71983510, Length=216, Percent_Identity=26.8518518518519, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221512771, Length=216, Percent_Identity=26.8518518518519, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24643674, Length=205, Percent_Identity=26.8292682926829, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI116007184, Length=192, Percent_Identity=27.6041666666667, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221500365, Length=192, Percent_Identity=27.6041666666667, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24666092, Length=202, Percent_Identity=26.7326732673267, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573571, Length=185, Percent_Identity=27.5675675675676, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573573, Length=185, Percent_Identity=27.5675675675676, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648314, Length=202, Percent_Identity=24.7524752475248, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582014, Length=189, Percent_Identity=28.042328042328, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24582012, Length=189, Percent_Identity=28.042328042328, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.30 [C]

Molecular weight: Translated: 29835; Mature: 29835

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: PS00061 ADH_SHORT ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKMSVVNSNAVKLAKSKHYTGVTNDNAILRVSNVSKKFVIQHNRSIKERLLNFRVSRA
CCCCCCCCCCCHHEEECCCCCCCCCCCCEEEEEECCCEEEEEECCHHHHHHHHHHHHHCC
NREPFWALKNITFELPIGSSVGLVGHNGSGKSTLLKLIGGIVRATEGEILSRGRISALIE
CCCCEEEEECEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHHH
LGAGFHPDLTGRENIYLNGSILGLTKAEIRRNFDSIVDFSGIEKFIDTQVKFYSSGMYMR
HCCCCCCCCCCCCEEEECCEEEECCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEE
LAFSVSVHTDPDLLLIDEILAVGDAPFQKKCLNKVTQFKNEGRSIVMVSHVAEQIETVCD
EEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHH
KVMVLKNGRLIYYGTTKVGLDLLRENYQ
HHEEEECCEEEEEECHHHHHHHHHHCCC
>Mature Secondary Structure
MKNKMSVVNSNAVKLAKSKHYTGVTNDNAILRVSNVSKKFVIQHNRSIKERLLNFRVSRA
CCCCCCCCCCCHHEEECCCCCCCCCCCCEEEEEECCCEEEEEECCHHHHHHHHHHHHHCC
NREPFWALKNITFELPIGSSVGLVGHNGSGKSTLLKLIGGIVRATEGEILSRGRISALIE
CCCCEEEEECEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHHH
LGAGFHPDLTGRENIYLNGSILGLTKAEIRRNFDSIVDFSGIEKFIDTQVKFYSSGMYMR
HCCCCCCCCCCCCEEEECCEEEECCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEE
LAFSVSVHTDPDLLLIDEILAVGDAPFQKKCLNKVTQFKNEGRSIVMVSHVAEQIETVCD
EEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHH
KVMVLKNGRLIYYGTTKVGLDLLRENYQ
HHEEEECCEEEEEECHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8626291 [H]