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The map label for this gene is ribE [H]

Identifier: 161501887

GI number: 161501887

Start: 801190

End: 801903

Strand: Direct

Name: ribE [H]

Synonym: TW707

Alternate gene names: 161501887

Gene position: 801190-801903 (Clockwise)

Preceding gene: 28572847

Following gene: 28572849

Centisome position: 86.53

GC content: 45.94

Gene sequence:

>714_bases
GTGTTCACGGGTCTTATAAAGAACAGAGGCGTAGTAAAAGACATTGTGCGCATCCGCGGGCAAAAAAGCATGGGTGCGCA
TAAGAATGACATTGCAGGGCAAATTACTGAAACCGACAGCGTCAGAAAGATAGGGGTTGCAATACCTCGCCAGCATTTAG
TGCAACAACCCAAAGTAGGAGATTCAGTCAGTGTGAATGGTGTGTGCCTTACCGTTCGTGAGGTGCACGAAGATGTCTTT
GTGTTCGATATCAGTCAGGTAACAGCCGATGCTACAACAATAAACGTATGGGATGTGGGTCAATTTGTCAATATTGAAAT
GCCGCTTACTCCATCCGACCCAATTGGGGGACATATAGTCCAAGGGCATGTTGATGGGGTTGGCATGATAGAGCAAATAA
TCGACAATTGCTTACGAATAAAAATACCTGACAGTTTATCTTTGCTGGTTGTAAAGAGTGGCTCGATAGCCGTTGATGGC
GTTTCGTTAACCGTTGTAAATGTCTCCGAACAATTGCCGAGCACAGCCAATGTATCGGGCAACCACGGAAAGCAGAATTG
CGCAAATTCGTGGTTTGAAATAAACTTGATCCCAGAGACTCTTGAGAGGACGACTCTCGGAGGTTTGCAAGTCGGCCAGT
TTGTAAATCTTGAGACCGACGTCCTGGCAAGACATGTGCGCAGGTTCATGTCGCTTGTAAATTCATTTTCCTGA

Upstream 100 bases:

>100_bases
TTTTGGTGATAACAACCTTTTAATAAGGGCGATTAAACCTATTCAATGCAACCCTGATACTCGCACATATCGTACTAAAA
AACATCTCCGGGACTGAATT

Downstream 100 bases:

>100_bases
GGTATTTTCGTAAGAATAGGCAGTTTGTGCGACATATCCCCGATGCCCTGAATGCCCTTAGGGCCGGCAGGCCGGTTGTC
GTCTTAGACGATAAAAATCG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MFTGLIKNRGVVKDIVRIRGQKSMGAHKNDIAGQITETDSVRKIGVAIPRQHLVQQPKVGDSVSVNGVCLTVREVHEDVF
VFDISQVTADATTINVWDVGQFVNIEMPLTPSDPIGGHIVQGHVDGVGMIEQIIDNCLRIKIPDSLSLLVVKSGSIAVDG
VSLTVVNVSEQLPSTANVSGNHGKQNCANSWFEINLIPETLERTTLGGLQVGQFVNLETDVLARHVRRFMSLVNSFS

Sequences:

>Translated_237_residues
MFTGLIKNRGVVKDIVRIRGQKSMGAHKNDIAGQITETDSVRKIGVAIPRQHLVQQPKVGDSVSVNGVCLTVREVHEDVF
VFDISQVTADATTINVWDVGQFVNIEMPLTPSDPIGGHIVQGHVDGVGMIEQIIDNCLRIKIPDSLSLLVVKSGSIAVDG
VSLTVVNVSEQLPSTANVSGNHGKQNCANSWFEINLIPETLERTTLGGLQVGQFVNLETDVLARHVRRFMSLVNSFS
>Mature_237_residues
MFTGLIKNRGVVKDIVRIRGQKSMGAHKNDIAGQITETDSVRKIGVAIPRQHLVQQPKVGDSVSVNGVCLTVREVHEDVF
VFDISQVTADATTINVWDVGQFVNIEMPLTPSDPIGGHIVQGHVDGVGMIEQIIDNCLRIKIPDSLSLLVVKSGSIAVDG
VSLTVVNVSEQLPSTANVSGNHGKQNCANSWFEINLIPETLERTTLGGLQVGQFVNLETDVLARHVRRFMSLVNSFS

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=191, Percent_Identity=34.0314136125654, Blast_Score=92, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319733, Length=189, Percent_Identity=31.2169312169312, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 25686; Mature: 25686

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGLIKNRGVVKDIVRIRGQKSMGAHKNDIAGQITETDSVRKIGVAIPRQHLVQQPKVG
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEECCCCHHHHHHCCCHHHHHCCCCCC
DSVSVNGVCLTVREVHEDVFVFDISQVTADATTINVWDVGQFVNIEMPLTPSDPIGGHIV
CCEECCEEEEEEEHHCCCEEEEEHHHHCCCCEEEEEEECCEEEEEEECCCCCCCCCCEEE
QGHVDGVGMIEQIIDNCLRIKIPDSLSLLVVKSGSIAVDGVSLTVVNVSEQLPSTANVSG
EECCCCHHHHHHHHHHHEEEECCCCEEEEEEECCCEEECCEEEEEEECHHHCCCCCCCCC
NHGKQNCANSWFEINLIPETLERTTLGGLQVGQFVNLETDVLARHVRRFMSLVNSFS
CCCCHHHCCCEEEEEECHHHHHHHHCCCEEECEEECCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFTGLIKNRGVVKDIVRIRGQKSMGAHKNDIAGQITETDSVRKIGVAIPRQHLVQQPKVG
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEECCCCHHHHHHCCCHHHHHCCCCCC
DSVSVNGVCLTVREVHEDVFVFDISQVTADATTINVWDVGQFVNIEMPLTPSDPIGGHIV
CCEECCEEEEEEEHHCCCEEEEEHHHHCCCCEEEEEEECCEEEEEEECCCCCCCCCCEEE
QGHVDGVGMIEQIIDNCLRIKIPDSLSLLVVKSGSIAVDGVSLTVVNVSEQLPSTANVSG
EECCCCHHHHHHHHHHHEEEECCCCEEEEEEECCCEEECCEEEEEEECHHHCCCCCCCCC
NHGKQNCANSWFEINLIPETLERTTLGGLQVGQFVNLETDVLARHVRRFMSLVNSFS
CCCCHHHCCCEEEEEECHHHHHHHHCCCEEECEEECCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]