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The map label for this gene is ribD [H]

Identifier: 28572847

GI number: 28572847

Start: 800071

End: 801186

Strand: Direct

Name: ribD [H]

Synonym: TW706

Alternate gene names: 28572847

Gene position: 800071-801186 (Clockwise)

Preceding gene: 28572846

Following gene: 161501887

Centisome position: 86.41

GC content: 47.04

Gene sequence:

>1116_bases
GTGTATATGAGAAGCTCGGCGTGTACTGACCTCTTTGTGTTGGCGATGCATAGAGCCATCACTATTGCTCAGCATGGCCC
CGTATTTGATAGGAATCCACAGGTTGGTTGTGTGATTTTGGATAGAGATTATCAACTAATCTCCCAAGGATGGCATATGG
GATCTGGTAGCGAGCATGCTGAGATAATGGCCCTTCGTGGTGCGAAATCTATTTTGAGCGAGCCATATGCTGCCGTTATT
ACCCTTGAACCATGTAGCAGCGCAGGACAGACAGGTCCATGCGTTAGGGCATTGCTTGATGCAGGTGTTAAGCATGTGGT
ATTTGGTGTACATGACCCGGAATCAAGTGGAGCAAAAGTCCTATCCGAAGCGGGGGTGAAAATTACATACGGGGTGCTTG
AGCGCGAGGTATGGGGGTTATGTGCGAAACACATACTGCCAAAAGTAAGAAAAACTCCATGGGTAATTGCCAAACGAGCA
CAAGGTCTTGATGGAAGGATGTCCGCGCCAGATGGGTCAAGTAAGTGGATAACAGGCCCGTACGCGAGGGGTCACGCGCA
TGTCATACGCTCGCAAGTTGATGCAATTGCAATCGGTTCAAATACCTTGTGTTGTGATAATCCGTCTCTACGCGCATTCC
ACCCGGCTGGCCATTTGTATGCAAAACAACCCAAGGTGGTAATTTTTTCTGGCAGGCCTCGTAGGTCAAATACGGCCGGC
CGTGGGTCGTGCGAACTCGGTAGATGCGTTAGAGGGCATGAATTTTTTGCGCGTGACCCAACCATCCTGTCTGGAAAAGA
TTTGAAAAAAGATATGCGCAGGCTATATGAATTAGGAGTACGATCTCTATTGCTTGAAGGCGGTCCGACACTTCTAAGTT
CCTTTGTTAGGGAAGATCTTGTCGATGAGTTTTATATATACACCGCGCCTAAGCTTCTTGGAGGAGGTTACGGAGATATT
AATATCGGGGTTGAATCAATTTCAGACAGCTTTGCCTTTCAATTGAACAGCGTTACGCGTTTTGGTGATAACAACCTTTT
AATAAGGGCGATTAAACCTATTCAATGCAACCCTGATACTCGCACATATCGTACTAAAAAACATCTCCGGGACTGA

Upstream 100 bases:

>100_bases
ACCAGAACAAATGAACTTCTCGATGATAAAAACTACATAAGGAAGATTCTCGTAACGGCTTCCGAACAGGCAAGAGGAGT
TGCGCAAAAAACAATAGATC

Downstream 100 bases:

>100_bases
ATTGTGTTCACGGGTCTTATAAAGAACAGAGGCGTAGTAAAAGACATTGTGCGCATCCGCGGGCAAAAAAGCATGGGTGC
GCATAAGAATGACATTGCAG

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MYMRSSACTDLFVLAMHRAITIAQHGPVFDRNPQVGCVILDRDYQLISQGWHMGSGSEHAEIMALRGAKSILSEPYAAVI
TLEPCSSAGQTGPCVRALLDAGVKHVVFGVHDPESSGAKVLSEAGVKITYGVLEREVWGLCAKHILPKVRKTPWVIAKRA
QGLDGRMSAPDGSSKWITGPYARGHAHVIRSQVDAIAIGSNTLCCDNPSLRAFHPAGHLYAKQPKVVIFSGRPRRSNTAG
RGSCELGRCVRGHEFFARDPTILSGKDLKKDMRRLYELGVRSLLLEGGPTLLSSFVREDLVDEFYIYTAPKLLGGGYGDI
NIGVESISDSFAFQLNSVTRFGDNNLLIRAIKPIQCNPDTRTYRTKKHLRD

Sequences:

>Translated_371_residues
MYMRSSACTDLFVLAMHRAITIAQHGPVFDRNPQVGCVILDRDYQLISQGWHMGSGSEHAEIMALRGAKSILSEPYAAVI
TLEPCSSAGQTGPCVRALLDAGVKHVVFGVHDPESSGAKVLSEAGVKITYGVLEREVWGLCAKHILPKVRKTPWVIAKRA
QGLDGRMSAPDGSSKWITGPYARGHAHVIRSQVDAIAIGSNTLCCDNPSLRAFHPAGHLYAKQPKVVIFSGRPRRSNTAG
RGSCELGRCVRGHEFFARDPTILSGKDLKKDMRRLYELGVRSLLLEGGPTLLSSFVREDLVDEFYIYTAPKLLGGGYGDI
NIGVESISDSFAFQLNSVTRFGDNNLLIRAIKPIQCNPDTRTYRTKKHLRD
>Mature_371_residues
MYMRSSACTDLFVLAMHRAITIAQHGPVFDRNPQVGCVILDRDYQLISQGWHMGSGSEHAEIMALRGAKSILSEPYAAVI
TLEPCSSAGQTGPCVRALLDAGVKHVVFGVHDPESSGAKVLSEAGVKITYGVLEREVWGLCAKHILPKVRKTPWVIAKRA
QGLDGRMSAPDGSSKWITGPYARGHAHVIRSQVDAIAIGSNTLCCDNPSLRAFHPAGHLYAKQPKVVIFSGRPRRSNTAG
RGSCELGRCVRGHEFFARDPTILSGKDLKKDMRRLYELGVRSLLLEGGPTLLSSFVREDLVDEFYIYTAPKLLGGGYGDI
NIGVESISDSFAFQLNSVTRFGDNNLLIRAIKPIQCNPDTRTYRTKKHLRD

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=366, Percent_Identity=31.6939890710383, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40642; Mature: 40642

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMRSSACTDLFVLAMHRAITIAQHGPVFDRNPQVGCVILDRDYQLISQGWHMGSGSEHA
CCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCHHHHHCCCCCCCCCCCE
EIMALRGAKSILSEPYAAVITLEPCSSAGQTGPCVRALLDAGVKHVVFGVHDPESSGAKV
EEEEECCHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCHHH
LSEAGVKITYGVLEREVWGLCAKHILPKVRKTPWVIAKRAQGLDGRMSAPDGSSKWITGP
HHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHCCCCCCCCCCCCCCCCCEECC
YARGHAHVIRSQVDAIAIGSNTLCCDNPSLRAFHPAGHLYAKQPKVVIFSGRPRRSNTAG
CCCCHHHHHHHCCCEEEECCCEEEECCCCCEEECCCCCEEECCCCEEEECCCCCCCCCCC
RGSCELGRCVRGHEFFARDPTILSGKDLKKDMRRLYELGVRSLLLEGGPTLLSSFVREDL
CCCCCHHHHHCCCHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VDEFYIYTAPKLLGGGYGDINIGVESISDSFAFQLNSVTRFGDNNLLIRAIKPIQCNPDT
HHHHEEEECHHHHCCCCCEEECCHHHHCCCCEEEECCEEEECCCCEEEEEECCEECCCCC
RTYRTKKHLRD
CHHHHHHHCCC
>Mature Secondary Structure
MYMRSSACTDLFVLAMHRAITIAQHGPVFDRNPQVGCVILDRDYQLISQGWHMGSGSEHA
CCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCHHHHHCCCCCCCCCCCE
EIMALRGAKSILSEPYAAVITLEPCSSAGQTGPCVRALLDAGVKHVVFGVHDPESSGAKV
EEEEECCHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCHHH
LSEAGVKITYGVLEREVWGLCAKHILPKVRKTPWVIAKRAQGLDGRMSAPDGSSKWITGP
HHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHCCCCCCCCCCCCCCCCCEECC
YARGHAHVIRSQVDAIAIGSNTLCCDNPSLRAFHPAGHLYAKQPKVVIFSGRPRRSNTAG
CCCCHHHHHHHCCCEEEECCCEEEECCCCCEEECCCCCEEECCCCEEEECCCCCCCCCCC
RGSCELGRCVRGHEFFARDPTILSGKDLKKDMRRLYELGVRSLLLEGGPTLLSSFVREDL
CCCCCHHHHHCCCHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VDEFYIYTAPKLLGGGYGDINIGVESISDSFAFQLNSVTRFGDNNLLIRAIKPIQCNPDT
HHHHEEEECHHHHCCCCCEEECCHHHHCCCCEEEECCEEEECCCCEEEEEECCEECCCCC
RTYRTKKHLRD
CHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]