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The map label for this gene is btuD

Identifier: 326424073

GI number: 326424073

Start: 2843743

End: 2844507

Strand: Reverse

Name: btuD

Synonym: NA

Alternate gene names: 326424073

Gene position: 2844507-2843743 (Counterclockwise)

Preceding gene: 27366069

Following gene: 27366064

Centisome position: 86.67

GC content: 50.85

Gene sequence:

>765_bases
ATGCACATTAATTATATTAGTGTCGGAAATCGGCTTTTACCCCTGTCTTTTCAATGCGCTGCAGGTGAAAAAGTGTATGT
CGCGGGCCCAAACGGTTCTGGAAAAAGTACCTTATTGTCAGCCATTGCGGGCACACTGAGCTCGCGTGAAGGAGTCAAGG
GGGAAGTGTTGATCAACGAGACCTCTTTACTCACGCTGCCTTTAGCGGAACAAGCGATTTATCGGGCTTACCTGTGCCAG
CAATCGAGACCGGCGTTTAACGTCGATGTGTTTCAGATGTTGGCGCTCTCGTTACCGGTTGGAAGGCATGTGGCTGAGCC
AGAGGTTCAAGCGGCTGTGCGTAGAGTGGTGGAGTTGGTGCAAATGCAAGACAAGTTGCATCGTAGCGTGCAGGCCCTCT
CGGGTGGTGAATGGCAACGCGTGCGTCTAGCTGCGGTGTGCTTGCAAGTGTGGCGCTCGCTAAATCCTTACTCGCAATTG
CTGATCTTGGATGAGCCTGCCGCGCCACTGGATGTTGCCCAAGCGAAGTGGTTGTATCAACTTATCGATGAAATGGCTGC
GCAAGGCTTGGTGGTGATTGTCGCCAATCATGATCTCAATCGTGTTTATCAACATGCGGACAAGGTGTTGTTGCTCAACC
AAGGCGTGTTAACCGCTTATGGCTCCGCAGACGAAGTGATGAGTGTGGAAAATCTACAACAGGTATTTGAAACGCCAGTG
AAAAAAGTGGCCGTTGACGGGCAGCCGTATTTGATTTTCACTTAG

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: Vitamin B12 ABC transporter ATPase BtuD

Products: NA

Alternate protein names: Vitamin B12-transporting ATPase

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:
NA

Sequences:

>Translated_254_residues
MHINYISVGNRLLPLSFQCAAGEKVYVAGPNGSGKSTLLSAIAGTLSSREGVKGEVLINETSLLTLPLAEQAIYRAYLCQ
QSRPAFNVDVFQMLALSLPVGRHVAEPEVQAAVRRVVELVQMQDKLHRSVQALSGGEWQRVRLAAVCLQVWRSLNPYSQL
LILDEPAAPLDVAQAKWLYQLIDEMAAQGLVVIVANHDLNRVYQHADKVLLLNQGVLTAYGSADEVMSVENLQQVFETPV
KKVAVDGQPYLIFT
>Mature_254_residues
MHINYISVGNRLLPLSFQCAAGEKVYVAGPNGSGKSTLLSAIAGTLSSREGVKGEVLINETSLLTLPLAEQAIYRAYLCQ
QSRPAFNVDVFQMLALSLPVGRHVAEPEVQAAVRRVVELVQMQDKLHRSVQALSGGEWQRVRLAAVCLQVWRSLNPYSQL
LILDEPAAPLDVAQAKWLYQLIDEMAAQGLVVIVANHDLNRVYQHADKVLLLNQGVLTAYGSADEVMSVENLQQVFETPV
KKVAVDGQPYLIFT

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Escherichia coli, GI1788002, Length=254, Percent_Identity=38.5826771653543, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1786345, Length=248, Percent_Identity=33.8709677419355, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788761, Length=219, Percent_Identity=29.6803652968037, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790739, Length=247, Percent_Identity=27.9352226720648, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1788165, Length=228, Percent_Identity=32.4561403508772, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1789593, Length=223, Percent_Identity=25.1121076233184, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1786803, Length=230, Percent_Identity=25.2173913043478, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081791, Length=213, Percent_Identity=27.2300469483568, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790162, Length=232, Percent_Identity=28.0172413793103, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790467, Length=215, Percent_Identity=28.8372093023256, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI48994883, Length=222, Percent_Identity=29.2792792792793, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1788053, Length=195, Percent_Identity=32.8205128205128, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081834, Length=212, Percent_Identity=28.7735849056604, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790190, Length=215, Percent_Identity=25.1162790697674, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789873, Length=221, Percent_Identity=26.2443438914027, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786398, Length=218, Percent_Identity=28.4403669724771, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786698, Length=202, Percent_Identity=29.2079207920792, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789672, Length=209, Percent_Identity=23.9234449760766, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787370, Length=223, Percent_Identity=25.1121076233184, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787792, Length=235, Percent_Identity=24.6808510638298, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87081709, Length=217, Percent_Identity=26.2672811059908, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI48994997, Length=232, Percent_Identity=26.2931034482759, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786253, Length=219, Percent_Identity=26.9406392694064, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI87082267, Length=217, Percent_Identity=26.7281105990783, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787029, Length=210, Percent_Identity=22.3809523809524, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI48995001, Length=232, Percent_Identity=25.4310344827586, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081782, Length=211, Percent_Identity=27.4881516587678, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI145693107, Length=242, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787547, Length=222, Percent_Identity=27.4774774774775, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790544, Length=217, Percent_Identity=24.8847926267281, Blast_Score=61, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28574533, Length=214, Percent_Identity=27.5700934579439, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19920532, Length=221, Percent_Identity=26.6968325791855, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24580930, Length=221, Percent_Identity=26.6968325791855, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666092, Length=215, Percent_Identity=29.7674418604651, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI85724858, Length=195, Percent_Identity=27.1794871794872, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI85724856, Length=195, Percent_Identity=27.1794871794872, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580547, Length=195, Percent_Identity=27.1794871794872, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580551, Length=195, Percent_Identity=27.1794871794872, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580549, Length=195, Percent_Identity=27.1794871794872, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580545, Length=195, Percent_Identity=27.1794871794872, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI85724864, Length=219, Percent_Identity=25.1141552511416, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24580555, Length=219, Percent_Identity=25.1141552511416, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI85816269, Length=219, Percent_Identity=25.1141552511416, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24580553, Length=219, Percent_Identity=25.1141552511416, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI28574744, Length=188, Percent_Identity=29.7872340425532, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BTUD_VIBVU (Q8D928)

Other databases:

- EMBL:   AE016795
- RefSeq:   NP_761596.1
- ProteinModelPortal:   Q8D928
- SMR:   Q8D928
- GeneID:   1179626
- GenomeReviews:   AE016795_GR
- KEGG:   vvu:VV1_2781
- HOGENOM:   HBG758042
- OMA:   DEWPATE
- ProtClustDB:   PRK03695
- BioCyc:   VVUL216895:VV1_2781-MONOMER
- BRENDA:   3.6.3.33
- HAMAP:   MF_01005
- InterPro:   IPR003439
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: =3.6.3.33

Molecular weight: Translated: 27876; Mature: 27876

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHINYISVGNRLLPLSFQCAAGEKVYVAGPNGSGKSTLLSAIAGTLSSREGVKGEVLINE
CEEEEEECCCEEECEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
TSLLTLPLAEQAIYRAYLCQQSRPAFNVDVFQMLALSLPVGRHVAEPEVQAAVRRVVELV
CCEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
QMQDKLHRSVQALSGGEWQRVRLAAVCLQVWRSLNPYSQLLILDEPAAPLDVAQAKWLYQ
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
LIDEMAAQGLVVIVANHDLNRVYQHADKVLLLNQGVLTAYGSADEVMSVENLQQVFETPV
HHHHHHHCCEEEEEECCCHHHHHHHHCCEEEEECCEEEECCCHHHHHHHHHHHHHHHHHH
KKVAVDGQPYLIFT
HHEEECCCCEEEEC
>Mature Secondary Structure
MHINYISVGNRLLPLSFQCAAGEKVYVAGPNGSGKSTLLSAIAGTLSSREGVKGEVLINE
CEEEEEECCCEEECEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
TSLLTLPLAEQAIYRAYLCQQSRPAFNVDVFQMLALSLPVGRHVAEPEVQAAVRRVVELV
CCEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
QMQDKLHRSVQALSGGEWQRVRLAAVCLQVWRSLNPYSQLLILDEPAAPLDVAQAKWLYQ
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
LIDEMAAQGLVVIVANHDLNRVYQHADKVLLLNQGVLTAYGSADEVMSVENLQQVFETPV
HHHHHHHCCEEEEEECCCHHHHHHHHCCEEEEECCEEEECCCHHHHHHHHHHHHHHHHHH
KKVAVDGQPYLIFT
HHEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA