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The map label for this gene is rpiA

Identifier: 326423850

GI number: 326423850

Start: 1520598

End: 1521254

Strand: Reverse

Name: rpiA

Synonym: NA

Alternate gene names: 326423850

Gene position: 1521254-1520598 (Counterclockwise)

Preceding gene: 27364918

Following gene: 27364916

Centisome position: 46.35

GC content: 48.4

Gene sequence:

>657_bases
ATGACTCAAGATGAAATGAAAAAAGCCGCTGGTTGGGCAGCGCTCAAATATGTGGAAAAAGGCAGCATTGTTGGCGTAGG
AACAGGCTCAACGGTTAATCACTTCATCGATGCTCTTGGAACCATGAGTGAAGAGATCAAAGGTGCGGTATCCAGCTCTG
TTGCATCAACAGAGAAACTTGAAGCGCTAGGTATTAAAATTTTCGACTGCAATGAAGTCGCATCTTTAGACATTTATGTT
GATGGCGCGGACGAAATCAACGCCGATCGTGAAATGATCAAAGGCGGTGGCGCGGCGCTCACTCGCGAGAAGATCGTTGC
GGCGATTGCGGACAAGTTTATCTGTATCGTTGATGGCACAAAGGCTGTCGATGTTCTTGGGACTTTCCCTCTTCCTGTTG
AAGTCATCCCAATGGCTCGCTCATACGTTGCGCGTCAATTGGTTAAACTGGGTGGTGATCCTTGTTACCGCGAAGGGGTG
ATTACTGACAACGGTAACGTCATCCTTGATGTTTACGGTATGAAGATCACCAATCCAAAACAGCTGGAAGATCAGATCAA
CGGCATCCCAGGTGTCGTCACTGTCGGCCTATTTGCTCATCGCGGTGCTGACGTGGTCATTACCGGCACTCCAGAAGGCG
CCAAAATTGAGGAATAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: ribose 5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:
NA

Sequences:

>Translated_218_residues
MTQDEMKKAAGWAALKYVEKGSIVGVGTGSTVNHFIDALGTMSEEIKGAVSSSVASTEKLEALGIKIFDCNEVASLDIYV
DGADEINADREMIKGGGAALTREKIVAAIADKFICIVDGTKAVDVLGTFPLPVEVIPMARSYVARQLVKLGGDPCYREGV
ITDNGNVILDVYGMKITNPKQLEDQINGIPGVVTVGLFAHRGADVVITGTPEGAKIEE
>Mature_217_residues
TQDEMKKAAGWAALKYVEKGSIVGVGTGSTVNHFIDALGTMSEEIKGAVSSSVASTEKLEALGIKIFDCNEVASLDIYVD
GADEINADREMIKGGGAALTREKIVAAIADKFICIVDGTKAVDVLGTFPLPVEVIPMARSYVARQLVKLGGDPCYREGVI
TDNGNVILDVYGMKITNPKQLEDQINGIPGVVTVGLFAHRGADVVITGTPEGAKIEE

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=228, Percent_Identity=36.4035087719298, Blast_Score=113, Evalue=1e-25,
Organism=Escherichia coli, GI1789280, Length=215, Percent_Identity=74.4186046511628, Blast_Score=329, Evalue=8e-92,
Organism=Caenorhabditis elegans, GI17551758, Length=210, Percent_Identity=33.8095238095238, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324669, Length=225, Percent_Identity=30.6666666666667, Blast_Score=82, Evalue=7e-17,
Organism=Drosophila melanogaster, GI281364072, Length=207, Percent_Identity=32.8502415458937, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_VIBVU (Q8DC93)

Other databases:

- EMBL:   AE016795
- RefSeq:   NP_760445.1
- ProteinModelPortal:   Q8DC93
- SMR:   Q8DC93
- GeneID:   1178461
- GenomeReviews:   AE016795_GR
- KEGG:   vvu:VV1_1547
- HOGENOM:   HBG515603
- OMA:   DKSIVGV
- ProtClustDB:   PRK00702
- BioCyc:   VVUL216895:VV1_1547-MONOMER
- BRENDA:   5.3.1.6
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 22972; Mature: 22840

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDEMKKAAGWAALKYVEKGSIVGVGTGSTVNHFIDALGTMSEEIKGAVSSSVASTEKL
CCHHHHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALGIKIFDCNEVASLDIYVDGADEINADREMIKGGGAALTREKIVAAIADKFICIVDGT
HHHCEEEEECCCEEEEEEEECCCHHCCCCHHHHCCCCCHHHHHHHHHHHHCCEEEEECCC
KAVDVLGTFPLPVEVIPMARSYVARQLVKLGGDPCYREGVITDNGNVILDVYGMKITNPK
CEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCHHCCCEEECCCCEEEEEECEEECCHH
QLEDQINGIPGVVTVGLFAHRGADVVITGTPEGAKIEE
HHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
TQDEMKKAAGWAALKYVEKGSIVGVGTGSTVNHFIDALGTMSEEIKGAVSSSVASTEKL
CHHHHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALGIKIFDCNEVASLDIYVDGADEINADREMIKGGGAALTREKIVAAIADKFICIVDGT
HHHCEEEEECCCEEEEEEEECCCHHCCCCHHHHCCCCCHHHHHHHHHHHHCCEEEEECCC
KAVDVLGTFPLPVEVIPMARSYVARQLVKLGGDPCYREGVITDNGNVILDVYGMKITNPK
CEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCHHCCCEEECCCCEEEEEECEEECCHH
QLEDQINGIPGVVTVGLFAHRGADVVITGTPEGAKIEE
HHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA