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The map label for this gene is ygfA [H]

Identifier: 27364918

GI number: 27364918

Start: 1521307

End: 1521906

Strand: Reverse

Name: ygfA [H]

Synonym: VV1_1548

Alternate gene names: 27364918

Gene position: 1521906-1521307 (Counterclockwise)

Preceding gene: 27364919

Following gene: 326423850

Centisome position: 46.37

GC content: 49.5

Gene sequence:

>600_bases
ATGCAAAATCTTTCCCGGCAAGACATCCGTACACTTATCCGCCAAAGACGCAATCAATTATGCAGTGATACTCAATATCA
AGCTGCGCTGGATTTGACAGCCCACTTTGCCCAGCTCGATGAACTCACTGACGCGCAACACATCGCCCTCTATCTTTCTG
CTGACGGAGAGCTCGATACCAAACCGTTGATTGAATGGCTTTGGGAACTGGGTAAGCAAGTGTATCTCCCGGTCATCCAT
CCTTTTTCCAAAGGGCAGCTTCTTTTTCTGCACTACCATCGCCACACCGATTTGATCTACAACCGCTACGGTATCCTTGA
GCCCAAGCTTGATAAACGTCATATCATCCCACTCGCAGAGCTTGATTTAATTTGTACGCCACTGGTCGCCTTTGACAGTA
CAGGGCAAAGGCTCGGTATGGGAGGCGGCTACTATGACCGCACCTTAGAGCGTTGGTTTCGCACTGGCTTAGGTGCCAAG
CCTATCGGTATCGCCCATGATTGCCAGCATGTTGAGCAGCTACCTTGCGAAGTTTGGGATATTCCTTTGCCTAAGATCGT
GACCCCAAGCCAAATCTGGCAATGGGAAAACGACGTTTAA

Upstream 100 bases:

>100_bases
CTTGGCCCGTACCGAGAAGCCTACGGTAATCATTGCCGATCCGCCTTGAACCAGCTGGTTCAAGGGCCACAATCCGCGAC
GGCACTCTGGGGTATCCTCT

Downstream 100 bases:

>100_bases
CTCGTTATAATCGCGCGGCACGAACTATCCTTCATCAATTCAGGAGATGAGCATGACTCAAGATGAAATGAAAAAAGCCG
CTGGTTGGGCAGCGCTCAAA

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MQNLSRQDIRTLIRQRRNQLCSDTQYQAALDLTAHFAQLDELTDAQHIALYLSADGELDTKPLIEWLWELGKQVYLPVIH
PFSKGQLLFLHYHRHTDLIYNRYGILEPKLDKRHIIPLAELDLICTPLVAFDSTGQRLGMGGGYYDRTLERWFRTGLGAK
PIGIAHDCQHVEQLPCEVWDIPLPKIVTPSQIWQWENDV

Sequences:

>Translated_199_residues
MQNLSRQDIRTLIRQRRNQLCSDTQYQAALDLTAHFAQLDELTDAQHIALYLSADGELDTKPLIEWLWELGKQVYLPVIH
PFSKGQLLFLHYHRHTDLIYNRYGILEPKLDKRHIIPLAELDLICTPLVAFDSTGQRLGMGGGYYDRTLERWFRTGLGAK
PIGIAHDCQHVEQLPCEVWDIPLPKIVTPSQIWQWENDV
>Mature_199_residues
MQNLSRQDIRTLIRQRRNQLCSDTQYQAALDLTAHFAQLDELTDAQHIALYLSADGELDTKPLIEWLWELGKQVYLPVIH
PFSKGQLLFLHYHRHTDLIYNRYGILEPKLDKRHIIPLAELDLICTPLVAFDSTGQRLGMGGGYYDRTLERWFRTGLGAK
PIGIAHDCQHVEQLPCEVWDIPLPKIVTPSQIWQWENDV

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Escherichia coli, GI1789278, Length=186, Percent_Identity=54.8387096774194, Blast_Score=215, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6321031, Length=207, Percent_Identity=28.0193236714976, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161077430, Length=197, Percent_Identity=23.3502538071066, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 23096; Mature: 23096

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNLSRQDIRTLIRQRRNQLCSDTQYQAALDLTAHFAQLDELTDAQHIALYLSADGELDT
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCH
KPLIEWLWELGKQVYLPVIHPFSKGQLLFLHYHRHTDLIYNRYGILEPKLDKRHIIPLAE
HHHHHHHHHHCCEEEEHEECCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCHHH
LDLICTPLVAFDSTGQRLGMGGGYYDRTLERWFRTGLGAKPIGIAHDCQHVEQLPCEVWD
HHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHCC
IPLPKIVTPSQIWQWENDV
CCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MQNLSRQDIRTLIRQRRNQLCSDTQYQAALDLTAHFAQLDELTDAQHIALYLSADGELDT
CCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCH
KPLIEWLWELGKQVYLPVIHPFSKGQLLFLHYHRHTDLIYNRYGILEPKLDKRHIIPLAE
HHHHHHHHHHCCEEEEHEECCCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCHHH
LDLICTPLVAFDSTGQRLGMGGGYYDRTLERWFRTGLGAKPIGIAHDCQHVEQLPCEVWD
HHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHCC
IPLPKIVTPSQIWQWENDV
CCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]