Click here to switch to the map view.

The map label for this gene is gmhB [H]

Identifier: 326423683

GI number: 326423683

Start: 282619

End: 283185

Strand: Reverse

Name: gmhB [H]

Synonym: NA

Alternate gene names: 326423683

Gene position: 283185-282619 (Counterclockwise)

Preceding gene: 27363773

Following gene: 27363768

Centisome position: 8.63

GC content: 48.15

Gene sequence:

>567_bases
TTGGCAAAACCAGCTGTTTTTTTGGATCGTGATGGCGTGATTAACGTTGATCATGGTTACGTTCATGACGAGCACGACTT
TGAATACATTGAAGGGGTGTTTGAGGCGACGAAGGCCCTAAAGGATATGGGGTATCTTTTGGTGTTGGTCACCAATCAGT
CGGGGATTGCCCGTGGCAAATTTAGCGAAGATCGCTTCCTTTCTCTGACCCAATGGATGGATTGGAATTTTGCGGACAAC
GGCGTTGAGTTTGACGGCATTTATTACTGTCCGCACCATGCAGAACACGGTGTGGGGGATTACAAACAAGATTGTGATTG
TCGCAAACCAAAACCTGGGATGTTTATCTCAGCGCGTGATTTCCTCAAAATCGATATGGCTCGCTCAGTGATGGTGGGTG
ACAAAGCCGAAGATATGATGGCTGCCGAAGCGGCAGGGGTTGCAACTAAGATTCTGGTACGCACTGGCAAACCTGTCACA
CAGCAGGGTGAGCAACTGGCAACCGTGGTGCTCGATAGCATCCGTGATGTGCCACTTTATGTAAAAGAACAAGTAAAAGG
TCGCTAA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:
NA

Sequences:

>Translated_188_residues
MAKPAVFLDRDGVINVDHGYVHDEHDFEYIEGVFEATKALKDMGYLLVLVTNQSGIARGKFSEDRFLSLTQWMDWNFADN
GVEFDGIYYCPHHAEHGVGDYKQDCDCRKPKPGMFISARDFLKIDMARSVMVGDKAEDMMAAEAAGVATKILVRTGKPVT
QQGEQLATVVLDSIRDVPLYVKEQVKGR
>Mature_187_residues
AKPAVFLDRDGVINVDHGYVHDEHDFEYIEGVFEATKALKDMGYLLVLVTNQSGIARGKFSEDRFLSLTQWMDWNFADNG
VEFDGIYYCPHHAEHGVGDYKQDCDCRKPKPGMFISARDFLKIDMARSVMVGDKAEDMMAAEAAGVATKILVRTGKPVTQ
QGEQLATVVLDSIRDVPLYVKEQVKGR

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=188, Percent_Identity=62.7659574468085, Blast_Score=252, Evalue=1e-68,
Organism=Escherichia coli, GI87082027, Length=170, Percent_Identity=30.5882352941176, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.1.-

Molecular weight: Translated: 21081; Mature: 20950

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPAVFLDRDGVINVDHGYVHDEHDFEYIEGVFEATKALKDMGYLLVLVTNQSGIARGK
CCCCCEEECCCCEEECCCCEECCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
FSEDRFLSLTQWMDWNFADNGVEFDGIYYCPHHAEHGVGDYKQDCDCRKPKPGMFISARD
CCCCHHEEHHHHCCCCCCCCCEEECEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEHHH
FLKIDMARSVMVGDKAEDMMAAEAAGVATKILVRTGKPVTQQGEQLATVVLDSIRDVPLY
HEEHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHH
VKEQVKGR
HHHHCCCC
>Mature Secondary Structure 
AKPAVFLDRDGVINVDHGYVHDEHDFEYIEGVFEATKALKDMGYLLVLVTNQSGIARGK
CCCCEEECCCCEEECCCCEECCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
FSEDRFLSLTQWMDWNFADNGVEFDGIYYCPHHAEHGVGDYKQDCDCRKPKPGMFISARD
CCCCHHEEHHHHCCCCCCCCCEEECEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEHHH
FLKIDMARSVMVGDKAEDMMAAEAAGVATKILVRTGKPVTQQGEQLATVVLDSIRDVPLY
HEEHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHH
VKEQVKGR
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301; 12101286 [H]