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The map label for this gene is treR [H]

Identifier: 27363768

GI number: 27363768

Start: 281633

End: 282580

Strand: Reverse

Name: treR [H]

Synonym: VV1_0290

Alternate gene names: 27363768

Gene position: 282580-281633 (Counterclockwise)

Preceding gene: 326423683

Following gene: 326423682

Centisome position: 8.61

GC content: 48.63

Gene sequence:

>948_bases
ATGAGCAAAAAGCTGACTATTCTTGATATTGCCCGTTTGTCTGGGGTCGGTAAATCGACCGTCTCGCGCGTGCTGACCAA
TGATCCCAAGGTAAAACCTGAAACCCGAGCGAAGGTAGAACAGGTGATACAAGATTCCGGTTATGTGCCTTCTAAATCCG
CTCAATCGATGCGTGGCGGTAGCCAGAAGGTGGTTGGGGTAATTATCTCGCGTCTCGACTCTCCCTCAGAAAATCGTGCT
GTAGGTAGTATGCTTAATGTGCTGTATCAAGCGGGATACGATGCGGTGATCATGGAGAGTCAGTTCGATCGCGAGAAAAC
CAACGAGCACTTAGAAGTGCTGCGTCGTCGCAATGTCGATGGCGTCATTGTGTTTGGCTTTACCGATATCGATCTACAAA
CCTTAGCCAGTTGGCAAGATCGAGCCGTGGTGATTGCCACGCCTGCGGAAGAGGTGTCTTCGATTAACTACGATAATCAG
CGCGTGATTGAGCTGGCGTTAGAACACTTGCAATCTTTATCGCTGAGCCATATCGCTTATATCGGTGTGAATAAAGAAGA
TAAAACCACGGGCTGGTCGCGTTTGAATGCCTACTTGTCGTGGTGCCAAAAACACGATGTTGAAGCTCGTTATCAAACTG
GCAAACTCAACCATGAGAGTGCTTATCACTTAGTTGATGAGGTGTTAGCGGAAAACACTCAAGCGATTGTCTGTGCGAGC
GATACCTTGGCTTTGGGCGTCATCAAGCGACTTCAAGAACTGGGGCGCGAAGAGGTTTGTGTCACTGGTGTGGGTGGCAA
TGAGTTGCTCTCTTTTCTTTTTCCAAAGGTGTTCAGTGTCGATCCCGGTTACAAGCAAGCGGGAGAAAAGGCCGCTAAGA
TGCTGATTTCTCAGATGAATGGTGAGGAAGCTATCTCGCACATCACTCAGGCACCGATCCAAAACTAA

Upstream 100 bases:

>100_bases
TGGTGCTCGATAGCATCCGTGATGTGCCTCTTTATGTAAAAGAACAAGTGGGAGGTCGCTAAGCGGCCTTTTTATTATTG
AACGTCTTTCTTGGCCTATT

Downstream 100 bases:

>100_bases
CCCTTTCATTTTTCTTGTTTTTCCGATCTAGACTGTGATCACTTTCAATTAATGGGACTGTTCCCATTTTGTTTATTTAT
AAAAACTGGCAATATTAAAT

Product: trehalose repressor

Products: NA

Alternate protein names: Trehalose operon repressor [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSKKLTILDIARLSGVGKSTVSRVLTNDPKVKPETRAKVEQVIQDSGYVPSKSAQSMRGGSQKVVGVIISRLDSPSENRA
VGSMLNVLYQAGYDAVIMESQFDREKTNEHLEVLRRRNVDGVIVFGFTDIDLQTLASWQDRAVVIATPAEEVSSINYDNQ
RVIELALEHLQSLSLSHIAYIGVNKEDKTTGWSRLNAYLSWCQKHDVEARYQTGKLNHESAYHLVDEVLAENTQAIVCAS
DTLALGVIKRLQELGREEVCVTGVGGNELLSFLFPKVFSVDPGYKQAGEKAAKMLISQMNGEEAISHITQAPIQN

Sequences:

>Translated_315_residues
MSKKLTILDIARLSGVGKSTVSRVLTNDPKVKPETRAKVEQVIQDSGYVPSKSAQSMRGGSQKVVGVIISRLDSPSENRA
VGSMLNVLYQAGYDAVIMESQFDREKTNEHLEVLRRRNVDGVIVFGFTDIDLQTLASWQDRAVVIATPAEEVSSINYDNQ
RVIELALEHLQSLSLSHIAYIGVNKEDKTTGWSRLNAYLSWCQKHDVEARYQTGKLNHESAYHLVDEVLAENTQAIVCAS
DTLALGVIKRLQELGREEVCVTGVGGNELLSFLFPKVFSVDPGYKQAGEKAAKMLISQMNGEEAISHITQAPIQN
>Mature_314_residues
SKKLTILDIARLSGVGKSTVSRVLTNDPKVKPETRAKVEQVIQDSGYVPSKSAQSMRGGSQKVVGVIISRLDSPSENRAV
GSMLNVLYQAGYDAVIMESQFDREKTNEHLEVLRRRNVDGVIVFGFTDIDLQTLASWQDRAVVIATPAEEVSSINYDNQR
VIELALEHLQSLSLSHIAYIGVNKEDKTTGWSRLNAYLSWCQKHDVEARYQTGKLNHESAYHLVDEVLAENTQAIVCASD
TLALGVIKRLQELGREEVCVTGVGGNELLSFLFPKVFSVDPGYKQAGEKAAKMLISQMNGEEAISHITQAPIQN

Specific function: Repressor of the treBC operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790689, Length=301, Percent_Identity=46.5116279069767, Blast_Score=275, Evalue=2e-75,
Organism=Escherichia coli, GI1790194, Length=309, Percent_Identity=26.2135922330097, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787906, Length=266, Percent_Identity=26.3157894736842, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789202, Length=287, Percent_Identity=25.0871080139373, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI48994940, Length=321, Percent_Identity=23.0529595015576, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790369, Length=312, Percent_Identity=22.1153846153846, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787580, Length=334, Percent_Identity=24.8502994011976, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786540, Length=320, Percent_Identity=24.0625, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790715, Length=318, Percent_Identity=22.0125786163522, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1786268, Length=306, Percent_Identity=24.1830065359477, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787948, Length=310, Percent_Identity=22.258064516129, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789068, Length=292, Percent_Identity=22.2602739726027, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761
- InterPro:   IPR012771 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 34746; Mature: 34615

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKLTILDIARLSGVGKSTVSRVLTNDPKVKPETRAKVEQVIQDSGYVPSKSAQSMRGG
CCCCEEHEEHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCC
SQKVVGVIISRLDSPSENRAVGSMLNVLYQAGYDAVIMESQFDREKTNEHLEVLRRRNVD
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCHHCHHHHHHHHHHHHHCCCC
GVIVFGFTDIDLQTLASWQDRAVVIATPAEEVSSINYDNQRVIELALEHLQSLSLSHIAY
EEEEEEEECCCHHHHHCCCCCEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHCCHHHEEE
IGVNKEDKTTGWSRLNAYLSWCQKHDVEARYQTGKLNHESAYHLVDEVLAENTQAIVCAS
EECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEC
DTLALGVIKRLQELGREEVCVTGVGGNELLSFLFPKVFSVDPGYKQAGEKAAKMLISQMN
HHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
GEEAISHITQAPIQN
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKKLTILDIARLSGVGKSTVSRVLTNDPKVKPETRAKVEQVIQDSGYVPSKSAQSMRGG
CCCEEHEEHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCC
SQKVVGVIISRLDSPSENRAVGSMLNVLYQAGYDAVIMESQFDREKTNEHLEVLRRRNVD
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEECCHHCHHHHHHHHHHHHHCCCC
GVIVFGFTDIDLQTLASWQDRAVVIATPAEEVSSINYDNQRVIELALEHLQSLSLSHIAY
EEEEEEEECCCHHHHHCCCCCEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHCCHHHEEE
IGVNKEDKTTGWSRLNAYLSWCQKHDVEARYQTGKLNHESAYHLVDEVLAENTQAIVCAS
EECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEC
DTLALGVIKRLQELGREEVCVTGVGGNELLSFLFPKVFSVDPGYKQAGEKAAKMLISQMN
HHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
GEEAISHITQAPIQN
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751273; 11677609 [H]