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The map label for this gene is hlyB [H]

Identifier: 27365879

GI number: 27365879

Start: 2622282

End: 2624144

Strand: Reverse

Name: hlyB [H]

Synonym: VV1_2583

Alternate gene names: 27365879

Gene position: 2624144-2622282 (Counterclockwise)

Preceding gene: 27365880

Following gene: 27365876

Centisome position: 79.96

GC content: 48.15

Gene sequence:

>1863_bases
ATGTCCGGATCACCTGTTCAAAAACGTTTTTTCTTTTCATTCTCTATCCGAGCCAAACTGCTGCTCATCAATGTGACTTT
GCTGTTAGGCGTTGCCGCCTACGCGATTTATGAGAACAACAGCGCAAAGCATTTGTCCTCTTTGGAGCACGCCTCAACAG
AAAACTTAAGCAGTTCCATTGATCTGTTGATGCTTCGCCGACACGAGAAAGATTATTTGGCTCGTCGCAGCGAAAAATAC
CTGACGAGTTTCGATAATACCTATTCTCAACTGCAACAGCGCATTGACCACTTATCAGACGTTCTTGCCAGTGAGTCGAT
TGCTATTGACGATCAACGTCAGCAAATTGTAACCACTCTATCTCAGTATCAAACTCAGTTTCATCAATTGGCCGCTCAGC
TAGCAAGCATTGACGCGTTGCAAAGTGAGCTATTTGCTGCACGCAGCGTGCTCAAAACCAATGTACTCAGTGCTAATGAT
GGAGAGCTTACCGCGCAGTTTTTGCAGTTGCTTGACCACGACTTCACTTTTGTCACCGAACCAACGCAAGAATACAAGGT
TGCGCTGCTCGAAGGGCTTCGCCAGTTTGCCAAGTTTGAAACCGATTTGTCTCCCGCTTTTACCGATTATTCCAACACCT
TATCTCGATACGTCAGCGCGATCGAAACGCTTGGCTTAACTGCAAACGAAGGTCTAAGAGGCGCGTTGCGTAGCAATGTG
CACAAAACCGAACAGGCGATTACCGATCTGCAAACCACCATTAAGCAAAGCGTTGAGCAAACTGCAGCGGATATTCGAAG
CTACTTACAGTGGATGGGTGTGGCGATCGTTGCGCTGTTGTCGTCACTGCTCTACGTCATTGGCCGTAGTATTCTTTCGA
GAATCAAAGCCATTAACCTCTTGATGGACGACATCGCAAATGGTAGCGGAGATTTGACGGTACGAATGAATGCAAAAGGC
AGTGATGAGCTTGCGCAGTTATCGCGTTCATTTGACCTCTTTATAAGCCACCTACATGACAACATCAAACAGCTGGCGTC
CGTGATGAGCGTTCTTGGCGAGAATTCATGCAGCTCAGAGCAAGCAGCGCAGAAAAGTATGCAAAACGCGCAGCAGCAGA
AGTTAGAGTCCGAGTCTGTTGCAACAGCGGTGAATGAACTGGTGATGACGACCAATGAGATCACCGCCAATATTGAATCG
GCTGCGCAAAATGCGCAACGAGTGAATACCGAAGCCGATAAAGCACTGCAACTCACCCACGCGACAGGTAAGCGAATTGA
TACGTTAGCCATCAGTATTGAAGAGTCGCAAGCGCAGATCCAAGCACTTGAAGCACAAAGCCGCGAAATCAATGCCGTTG
TCTCTGCCATTCAAGGCATTGCAGAGCAAACCAACCTGTTGGCATTAAATGCCGCCATAGAAGCGGCGCGCGCTGGAGAA
AGTGGCCGAGGGTTTGCTGTGGTCGCTGATGAAGTTCGTCAGCTCTCTCGCCTAACCAATGATTCCACCTTGCAAATTGA
ATCCACCGTACAAGCACTGACGAAAGGCATCACTCAAACAGTCAACAAAATGGCAGAGAGTGTCGATCAAGCTCGGACGA
CGAATGTGGATACGCGCCATGTGATCGAAGCGATTGAAGGCATCAGCACTCAAATCACCGAGATGTTTGATATGAACACG
CAGATTGCGACCGCGTCAGAAGAGCAATCAATGGTATCAGCAGAAATTGACCGCAATATTACGCAAATTGCGCAGCTTGC
GGGGGATACCTACGAGATCGTCTCTGGCTCTGTACGATGCAGCGAACAAGTGTCGGATGTTAGCCACAAGCTGGAAAAGA
TCGTTGCCCAATTTAAGTATTGA

Upstream 100 bases:

>100_bases
ATGCGCTATTAGTTGAGTATTCTCTGCAATAAATTTGAAACATAAATGAAACAAAAGCGGAGATGGGTTAACTACGTCAC
TGGCTAAATGGGAGGTATCC

Downstream 100 bases:

>100_bases
GCGCCCTAACCTACTTGCCGTCATCGACTGAGTGACGATAGGTAGTGGAAAAAGCAAAAGAGCCTCAGTGAGGCTCTTTG
TTTGATCTTTTTAAGCACGC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MSGSPVQKRFFFSFSIRAKLLLINVTLLLGVAAYAIYENNSAKHLSSLEHASTENLSSSIDLLMLRRHEKDYLARRSEKY
LTSFDNTYSQLQQRIDHLSDVLASESIAIDDQRQQIVTTLSQYQTQFHQLAAQLASIDALQSELFAARSVLKTNVLSAND
GELTAQFLQLLDHDFTFVTEPTQEYKVALLEGLRQFAKFETDLSPAFTDYSNTLSRYVSAIETLGLTANEGLRGALRSNV
HKTEQAITDLQTTIKQSVEQTAADIRSYLQWMGVAIVALLSSLLYVIGRSILSRIKAINLLMDDIANGSGDLTVRMNAKG
SDELAQLSRSFDLFISHLHDNIKQLASVMSVLGENSCSSEQAAQKSMQNAQQQKLESESVATAVNELVMTTNEITANIES
AAQNAQRVNTEADKALQLTHATGKRIDTLAISIEESQAQIQALEAQSREINAVVSAIQGIAEQTNLLALNAAIEAARAGE
SGRGFAVVADEVRQLSRLTNDSTLQIESTVQALTKGITQTVNKMAESVDQARTTNVDTRHVIEAIEGISTQITEMFDMNT
QIATASEEQSMVSAEIDRNITQIAQLAGDTYEIVSGSVRCSEQVSDVSHKLEKIVAQFKY

Sequences:

>Translated_620_residues
MSGSPVQKRFFFSFSIRAKLLLINVTLLLGVAAYAIYENNSAKHLSSLEHASTENLSSSIDLLMLRRHEKDYLARRSEKY
LTSFDNTYSQLQQRIDHLSDVLASESIAIDDQRQQIVTTLSQYQTQFHQLAAQLASIDALQSELFAARSVLKTNVLSAND
GELTAQFLQLLDHDFTFVTEPTQEYKVALLEGLRQFAKFETDLSPAFTDYSNTLSRYVSAIETLGLTANEGLRGALRSNV
HKTEQAITDLQTTIKQSVEQTAADIRSYLQWMGVAIVALLSSLLYVIGRSILSRIKAINLLMDDIANGSGDLTVRMNAKG
SDELAQLSRSFDLFISHLHDNIKQLASVMSVLGENSCSSEQAAQKSMQNAQQQKLESESVATAVNELVMTTNEITANIES
AAQNAQRVNTEADKALQLTHATGKRIDTLAISIEESQAQIQALEAQSREINAVVSAIQGIAEQTNLLALNAAIEAARAGE
SGRGFAVVADEVRQLSRLTNDSTLQIESTVQALTKGITQTVNKMAESVDQARTTNVDTRHVIEAIEGISTQITEMFDMNT
QIATASEEQSMVSAEIDRNITQIAQLAGDTYEIVSGSVRCSEQVSDVSHKLEKIVAQFKY
>Mature_619_residues
SGSPVQKRFFFSFSIRAKLLLINVTLLLGVAAYAIYENNSAKHLSSLEHASTENLSSSIDLLMLRRHEKDYLARRSEKYL
TSFDNTYSQLQQRIDHLSDVLASESIAIDDQRQQIVTTLSQYQTQFHQLAAQLASIDALQSELFAARSVLKTNVLSANDG
ELTAQFLQLLDHDFTFVTEPTQEYKVALLEGLRQFAKFETDLSPAFTDYSNTLSRYVSAIETLGLTANEGLRGALRSNVH
KTEQAITDLQTTIKQSVEQTAADIRSYLQWMGVAIVALLSSLLYVIGRSILSRIKAINLLMDDIANGSGDLTVRMNAKGS
DELAQLSRSFDLFISHLHDNIKQLASVMSVLGENSCSSEQAAQKSMQNAQQQKLESESVATAVNELVMTTNEITANIESA
AQNAQRVNTEADKALQLTHATGKRIDTLAISIEESQAQIQALEAQSREINAVVSAIQGIAEQTNLLALNAAIEAARAGES
GRGFAVVADEVRQLSRLTNDSTLQIESTVQALTKGITQTVNKMAESVDQARTTNVDTRHVIEAIEGISTQITEMFDMNTQ
IATASEEQSMVSAEIDRNITQIAQLAGDTYEIVSGSVRCSEQVSDVSHKLEKIVAQFKY

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=327, Percent_Identity=28.7461773700306, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788195, Length=301, Percent_Identity=29.2358803986711, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788194, Length=303, Percent_Identity=28.3828382838284, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1787690, Length=351, Percent_Identity=28.2051282051282, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789453, Length=252, Percent_Identity=29.3650793650794, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68105; Mature: 67974

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSPVQKRFFFSFSIRAKLLLINVTLLLGVAAYAIYENNSAKHLSSLEHASTENLSSSI
CCCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
DLLMLRRHEKDYLARRSEKYLTSFDNTYSQLQQRIDHLSDVLASESIAIDDQRQQIVTTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SQYQTQFHQLAAQLASIDALQSELFAARSVLKTNVLSANDGELTAQFLQLLDHDFTFVTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEC
PTQEYKVALLEGLRQFAKFETDLSPAFTDYSNTLSRYVSAIETLGLTANEGLRGALRSNV
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
HKTEQAITDLQTTIKQSVEQTAADIRSYLQWMGVAIVALLSSLLYVIGRSILSRIKAINL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMDDIANGSGDLTVRMNAKGSDELAQLSRSFDLFISHLHDNIKQLASVMSVLGENSCSSE
HHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QAAQKSMQNAQQQKLESESVATAVNELVMTTNEITANIESAAQNAQRVNTEADKALQLTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ATGKRIDTLAISIEESQAQIQALEAQSREINAVVSAIQGIAEQTNLLALNAAIEAARAGE
HCCCCEEHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SGRGFAVVADEVRQLSRLTNDSTLQIESTVQALTKGITQTVNKMAESVDQARTTNVDTRH
CCCCEEHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VIEAIEGISTQITEMFDMNTQIATASEEQSMVSAEIDRNITQIAQLAGDTYEIVSGSVRC
HHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHH
SEQVSDVSHKLEKIVAQFKY
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SGSPVQKRFFFSFSIRAKLLLINVTLLLGVAAYAIYENNSAKHLSSLEHASTENLSSSI
CCCCCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
DLLMLRRHEKDYLARRSEKYLTSFDNTYSQLQQRIDHLSDVLASESIAIDDQRQQIVTTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SQYQTQFHQLAAQLASIDALQSELFAARSVLKTNVLSANDGELTAQFLQLLDHDFTFVTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEC
PTQEYKVALLEGLRQFAKFETDLSPAFTDYSNTLSRYVSAIETLGLTANEGLRGALRSNV
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
HKTEQAITDLQTTIKQSVEQTAADIRSYLQWMGVAIVALLSSLLYVIGRSILSRIKAINL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMDDIANGSGDLTVRMNAKGSDELAQLSRSFDLFISHLHDNIKQLASVMSVLGENSCSSE
HHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QAAQKSMQNAQQQKLESESVATAVNELVMTTNEITANIESAAQNAQRVNTEADKALQLTH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
ATGKRIDTLAISIEESQAQIQALEAQSREINAVVSAIQGIAEQTNLLALNAAIEAARAGE
HCCCCEEHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SGRGFAVVADEVRQLSRLTNDSTLQIESTVQALTKGITQTVNKMAESVDQARTTNVDTRH
CCCCEEHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VIEAIEGISTQITEMFDMNTQIATASEEQSMVSAEIDRNITQIAQLAGDTYEIVSGSVRC
HHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHH
SEQVSDVSHKLEKIVAQFKY
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]