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The map label for this gene is uspA [H]

Identifier: 27364536

GI number: 27364536

Start: 1115960

End: 1116385

Strand: Reverse

Name: uspA [H]

Synonym: VV1_1115

Alternate gene names: 27364536

Gene position: 1116385-1115960 (Counterclockwise)

Preceding gene: 27364540

Following gene: 27364535

Centisome position: 34.02

GC content: 45.31

Gene sequence:

>426_bases
ATGAGTTATCAACACATTTTAGTCGCGGTTGATCTTTCTGACGACAGCAAGCTATTGATCGATAAAGCTGTTTCTTTAGC
AAAAGCTTTAGAAGCGAAAGTATCCTTTATTCATATTGATGTGAATTACGCCGAGCTGTACACCGGACTTATCGACATCA
ACATGGCCGAAGCACAACATCAGGCGATGGAAGCCTCGCGCACACAACTGGCGAATCTGGCGGAATATGCCAACTTCCCG
ATCACTCATACCTTGGTCGGCAGCGGCGATTTAAGCAATGAACTGTGTGACACCATTGGTGAGTACCAAGTGGATTTACT
GGTGTGCGGCCATCACCAAGATTTTTGGAGTAAACTGCTCTCTTCTACTCGTCAACTGATCAACTGCTCTCCGGTTGATA
TGTTGGTTGTACCACTTAAAGAGTGA

Upstream 100 bases:

>100_bases
ACATGGGATTGGATCTGAGATCCCTTTGGCAAAAAACTCTTCACCTAAGTGCTATGTTTTAACTATACCCGAGGGGGAAA
ACGATACAGGAGAGCACACC

Downstream 100 bases:

>100_bases
TTTTGCTTTTGCCCTTCTCGGCAAATCGGTAGACTGCGGACATTTGTTATTTACTCGTTATCACTATGTTTTATCTCTCC
GCAGTCACCCTGTTATGGGC

Product: Universal stress protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MSYQHILVAVDLSDDSKLLIDKAVSLAKALEAKVSFIHIDVNYAELYTGLIDINMAEAQHQAMEASRTQLANLAEYANFP
ITHTLVGSGDLSNELCDTIGEYQVDLLVCGHHQDFWSKLLSSTRQLINCSPVDMLVVPLKE

Sequences:

>Translated_141_residues
MSYQHILVAVDLSDDSKLLIDKAVSLAKALEAKVSFIHIDVNYAELYTGLIDINMAEAQHQAMEASRTQLANLAEYANFP
ITHTLVGSGDLSNELCDTIGEYQVDLLVCGHHQDFWSKLLSSTRQLINCSPVDMLVVPLKE
>Mature_140_residues
SYQHILVAVDLSDDSKLLIDKAVSLAKALEAKVSFIHIDVNYAELYTGLIDINMAEAQHQAMEASRTQLANLAEYANFPI
THTLVGSGDLSNELCDTIGEYQVDLLVCGHHQDFWSKLLSSTRQLINCSPVDMLVVPLKE

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1789909, Length=141, Percent_Identity=58.8652482269503, Blast_Score=179, Evalue=5e-47,
Organism=Escherichia coli, GI1790358, Length=139, Percent_Identity=33.0935251798561, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI1788205, Length=140, Percent_Identity=32.1428571428571, Blast_Score=79, Evalue=1e-16,

Paralogues:

None

Copy number: 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 290 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4003 Molecules/Cell In: Growth Phase, G

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 15605; Mature: 15474

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQHILVAVDLSDDSKLLIDKAVSLAKALEAKVSFIHIDVNYAELYTGLIDINMAEAQH
CCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEEEECHHHHHHHHHHCCCHHHHHH
QAMEASRTQLANLAEYANFPITHTLVGSGDLSNELCDTIGEYQVDLLVCGHHQDFWSKLL
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCEEEEEEEECCCHHHHHHHH
SSTRQLINCSPVDMLVVPLKE
HHHHHHHCCCCCCEEEEEECC
>Mature Secondary Structure 
SYQHILVAVDLSDDSKLLIDKAVSLAKALEAKVSFIHIDVNYAELYTGLIDINMAEAQH
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEEEEECHHHHHHHHHHCCCHHHHHH
QAMEASRTQLANLAEYANFPITHTLVGSGDLSNELCDTIGEYQVDLLVCGHHQDFWSKLL
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCEEEEEEEECCCHHHHHHHH
SSTRQLINCSPVDMLVVPLKE
HHHHHHHCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]