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The map label for this gene is hemY [H]

Identifier: 27364540

GI number: 27364540

Start: 1118862

End: 1120043

Strand: Reverse

Name: hemY [H]

Synonym: VV1_1119

Alternate gene names: 27364540

Gene position: 1120043-1118862 (Counterclockwise)

Preceding gene: 27364541

Following gene: 27364536

Centisome position: 34.13

GC content: 50.42

Gene sequence:

>1182_bases
ATGATTCGTTTGATCTTCCTCTTTGTCGTGCTTGGTGCCGGGCTGTTTGTCGGTACCCAGTTTTCTGGCCAGCAGGGTTA
TGTGCTGATCTCGATCGCCAACACCACGATTGAAATGAGCGTCACCACCTTGGTGATTTTCATTGTCGCGGCTTTGGCCG
GTTTGTTTGGCTTAGAATACCTAGTTAAAAAAGTACTCTATACCGGTTTCACCACGTGGAACTGGTTTAGCGTACGCAAA
ATGCGCCGCTCTCGTCGTTACACCAACGAAGGCATCATCAAGTTGTTGGAAGGCGACTGGAAAGGCGCAGAGAAGAAAGT
GACACGCTGGGCCAACCATCATGACATGCCTCTGCTTTGTTACTTAGTGGCCTCAGAAGCAGCGGATGGCCAAGGTGACA
AAGCCAAGCGCGATCACTACTTAGCATTGGCTGCCGAGCAAGAAAATGCCTACTTGGCGGTAGAGCTAACCCGATCAAAG
CAGTTGGTACGAGAGGGCGAATTTGCGCTGGCGTTTGATAGCTTGCAGTCTCTCAAAGGTCGCTACCCTAATAATCCGAT
TGTGCTGAACTTGCTCAAAACCACTTACCTAGAGCTCAAGTTATGGCAGCCTCTGATTGACCTCTTGCCAACACTCAACA
AGCAAGCGTTGATCTCCCCAGAGGACGCCGAACAGATGCACCAACGAGCTCAGTGCGGTTTACTGGCCGACGTTGCTGGG
CAGCAAGGCAGTGAAGGATTAATCAAACACTGGAATACACTGCCACGCAAAGTCAAACAAGATCCACATTTGGTGGCCTG
CTTTGCCAAACAGTTGATTGCCCGTAAAGCCGACCACGAAGCACTCACCGTGATCAAAGAAGCACTGAAAAAATCACCAT
CGCCAGAGCTGTACGCACTACTGCCACAACTCAACCTTAGCGATGTGCATCCTGTGATTGTGATGCTCGAACAGAATGTG
AAAAACGACAACCACAACGCCGAAGCGCACAGCGCACTGGCGCAGTTGTATTTCCGTGAAGGCAAATGGCCACAAGCACA
GTCGCACTTTGAAACGGCACTGAAAGTACGTTCGAGTGTTTCCGACTACGCTTTCCTAGCCGATGCGCTTGAGAAGCAAA
ACCTCAACAAAGCCGCGCATGAAGTGTCACGTAAAGCGCTGACGCTGGTACAAAATCACTGA

Upstream 100 bases:

>100_bases
AATACCCTGTAAAACTGCAAACGCAAAATCAATTGGCGGATGTAATTCGTGAACGTCTACGCCGTGAAGTCACTAGCATG
ACCAGCACGGAGGCGCAGCA

Downstream 100 bases:

>100_bases
TTCTTGGTGAAAGAGATAACCTGTAAAAGCAAAGGGACGGTTGAACCGTCCCTCTGTTTTTTTATTGGTGTTTCCTTGAG
CTTACACCCACTGCCCCGCG

Product: HemY-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MIRLIFLFVVLGAGLFVGTQFSGQQGYVLISIANTTIEMSVTTLVIFIVAALAGLFGLEYLVKKVLYTGFTTWNWFSVRK
MRRSRRYTNEGIIKLLEGDWKGAEKKVTRWANHHDMPLLCYLVASEAADGQGDKAKRDHYLALAAEQENAYLAVELTRSK
QLVREGEFALAFDSLQSLKGRYPNNPIVLNLLKTTYLELKLWQPLIDLLPTLNKQALISPEDAEQMHQRAQCGLLADVAG
QQGSEGLIKHWNTLPRKVKQDPHLVACFAKQLIARKADHEALTVIKEALKKSPSPELYALLPQLNLSDVHPVIVMLEQNV
KNDNHNAEAHSALAQLYFREGKWPQAQSHFETALKVRSSVSDYAFLADALEKQNLNKAAHEVSRKALTLVQNH

Sequences:

>Translated_393_residues
MIRLIFLFVVLGAGLFVGTQFSGQQGYVLISIANTTIEMSVTTLVIFIVAALAGLFGLEYLVKKVLYTGFTTWNWFSVRK
MRRSRRYTNEGIIKLLEGDWKGAEKKVTRWANHHDMPLLCYLVASEAADGQGDKAKRDHYLALAAEQENAYLAVELTRSK
QLVREGEFALAFDSLQSLKGRYPNNPIVLNLLKTTYLELKLWQPLIDLLPTLNKQALISPEDAEQMHQRAQCGLLADVAG
QQGSEGLIKHWNTLPRKVKQDPHLVACFAKQLIARKADHEALTVIKEALKKSPSPELYALLPQLNLSDVHPVIVMLEQNV
KNDNHNAEAHSALAQLYFREGKWPQAQSHFETALKVRSSVSDYAFLADALEKQNLNKAAHEVSRKALTLVQNH
>Mature_393_residues
MIRLIFLFVVLGAGLFVGTQFSGQQGYVLISIANTTIEMSVTTLVIFIVAALAGLFGLEYLVKKVLYTGFTTWNWFSVRK
MRRSRRYTNEGIIKLLEGDWKGAEKKVTRWANHHDMPLLCYLVASEAADGQGDKAKRDHYLALAAEQENAYLAVELTRSK
QLVREGEFALAFDSLQSLKGRYPNNPIVLNLLKTTYLELKLWQPLIDLLPTLNKQALISPEDAEQMHQRAQCGLLADVAG
QQGSEGLIKHWNTLPRKVKQDPHLVACFAKQLIARKADHEALTVIKEALKKSPSPELYALLPQLNLSDVHPVIVMLEQNV
KNDNHNAEAHSALAQLYFREGKWPQAQSHFETALKVRSSVSDYAFLADALEKQNLNKAAHEVSRKALTLVQNH

Specific function: Involved in a late step of protoheme IX synthesis [H]

COG id: COG3071

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1790234, Length=379, Percent_Identity=33.7730870712401, Blast_Score=212, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010817
- InterPro:   IPR005254
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR013105
- InterPro:   IPR019734 [H]

Pfam domain/function: PF07219 HemY_N; PF07719 TPR_2 [H]

EC number: NA

Molecular weight: Translated: 44178; Mature: 44178

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLIFLFVVLGAGLFVGTQFSGQQGYVLISIANTTIEMSVTTLVIFIVAALAGLFGLEY
CHHHHHHHHHHHCHHHEECEECCCCCEEEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHH
LVKKVLYTGFTTWNWFSVRKMRRSRRYTNEGIIKLLEGDWKGAEKKVTRWANHHDMPLLC
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHEEECCCCCCHHHHHHHHCCCCCCHHEE
YLVASEAADGQGDKAKRDHYLALAAEQENAYLAVELTRSKQLVREGEFALAFDSLQSLKG
HHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEHHHHHHHHCCCCEEHHHHHHHHCC
RYPNNPIVLNLLKTTYLELKLWQPLIDLLPTLNKQALISPEDAEQMHQRAQCGLLADVAG
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHCC
QQGSEGLIKHWNTLPRKVKQDPHLVACFAKQLIARKADHEALTVIKEALKKSPSPELYAL
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEE
LPQLNLSDVHPVIVMLEQNVKNDNHNAEAHSALAQLYFREGKWPQAQSHFETALKVRSSV
ECCCCCCCCCCEEEEEEHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SDYAFLADALEKQNLNKAAHEVSRKALTLVQNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRLIFLFVVLGAGLFVGTQFSGQQGYVLISIANTTIEMSVTTLVIFIVAALAGLFGLEY
CHHHHHHHHHHHCHHHEECEECCCCCEEEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHH
LVKKVLYTGFTTWNWFSVRKMRRSRRYTNEGIIKLLEGDWKGAEKKVTRWANHHDMPLLC
HHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHEEECCCCCCHHHHHHHHCCCCCCHHEE
YLVASEAADGQGDKAKRDHYLALAAEQENAYLAVELTRSKQLVREGEFALAFDSLQSLKG
HHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEHHHHHHHHCCCCEEHHHHHHHHCC
RYPNNPIVLNLLKTTYLELKLWQPLIDLLPTLNKQALISPEDAEQMHQRAQCGLLADVAG
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHCC
QQGSEGLIKHWNTLPRKVKQDPHLVACFAKQLIARKADHEALTVIKEALKKSPSPELYAL
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEE
LPQLNLSDVHPVIVMLEQNVKNDNHNAEAHSALAQLYFREGKWPQAQSHFETALKVRSSV
ECCCCCCCCCCEEEEEEHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SDYAFLADALEKQNLNKAAHEVSRKALTLVQNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]