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The map label for this gene is htpG

Identifier: 27363671

GI number: 27363671

Start: 180902

End: 182806

Strand: Reverse

Name: htpG

Synonym: VV1_0189

Alternate gene names: 27363671

Gene position: 182806-180902 (Counterclockwise)

Preceding gene: 27363676

Following gene: 27363670

Centisome position: 5.57

GC content: 46.3

Gene sequence:

>1905_bases
ATGAACGAGACAGTAGCAAATAACAAAGAAACTCGTGGCTTTCAGTCAGAGGTAAAACAACTTCTCCATCTGATGATCCA
CTCACTGTATTCCAATAAAGAAATCTTCCTACGTGAGTTGATCTCCAACGCCTCCGACGCAGCCGATAAACTGCGTTTTC
AAGCGTTGTCCAATCCTGCTCTTTATGAAAATGATGCAGAATTGGGCGTGAAGCTTTCTTTTAACGAAGAACATAACACG
CTGACGATTTCCGATAACGGGATTGGTATGAGCCGCGAAGAGGTGATTTCGCATTTGGGCACCATTGCCAAATCTGGTAC
GGCGGAGTTTTTCTCTAAACTATCTCAAGAGCAATCAAAAGATTCTCAGCTGATTGGTCAGTTTGGTGTTGGTTTCTATT
CAGCCTTCATTGTGGCTGATGCAGTGACGGTACGAACTCGAGCGGCGGGTCTTAGCGCAGACCAAGCGGTACTTTGGCAT
TCTGCAGGTGAAGGTGAATACACCGTTGAAGACATTACCAAAGAATCACGTGGTACTGATATTATTCTGCACATGCGTGA
AGACGGCAAAGAGTTCCTCAACGAATGGCGTTTACGTGATGTGATTGGTAAGTATTCCGATCACATTGGCATTCCTGTTT
CTATTCAAACCCGTGTTCGCGATGAAGAAGGCAAAGAAACAGAAGAAGTGAAGTGGGAGCAAATCAATAAAGCCCAAGCA
CTTTGGACGCGCAATAAATCCGATATCTCAGACGAAGAGTATCAAGAGTTTTACAAGCATGTCTCTCACGATTTTGCTGA
CCCATTACTTTGGAGTCACAACCGAGTAGAAGGCAAAAACGACTATACCAGCCTCCTTTATATTCCATCGAAAGCGCCTT
GGGATATGATGAACCGTGACCATAAATCTGGTCTTAAACTCTATGTTCAGCGCGTTTTCATCATGGATGACGCTGAGCAA
TTTATGCCATCTTACTTGCGTTTTGTCCGCGGTTTGATTGACTCCAACGATCTGCCGCTCAACGTCTCTCGCGAGATCTT
GCAAGACAACAAGGTGACTCAATCGCTACGCGGTGCGTGCACTAAACGTGTTTTAACCATGCTCGAGCGCTTGGCGAAAA
ATGACACAGATAAATACCAAACTTTCTGGAAAGAATTTGGTTTGGTGATGAAGGAGGGTCCAGCCGAAGATTACGCCAAC
CGCGAGAAAGTGGCGTCGTTGTTACGCTTTGCCTCGACAGAAGTGGACTCTGCAGAGCAGACCGTTTCTCTTGAGTCTTA
TGTTGAGCGCATGAAAGAAGGCCAAGACAAGATCTACTACCTCACAGCAGACAGCTATGCGGCAGCGAAAAACAGCCCTC
ACCTAGAGCAGTTTAAAGCCAAAGGTCTTGAAGTTATCTTAATGTTTGACCGTATTGACGAATGGTTGATGAACTACCTA
ACAGAGTTTGATGGTAAGCAGTTCCAGTCAATCACGAAAGCGGGCCTTGATCTTAGCCAATTTGAAGATGAGCAAGAGAA
AGAGAAGCAGAAAGAAACGGAACAAGAGTTCCAGTCCGTGGTTGAGCGCACCAAGAGCTACTTGGGTGATCGTGTGAAAG
AGGTGCGTACCACCTTTAAGCTAGCGAATACCCCAGCGGTGGTGGTGACCGATGATTTCGAAATGGGCACACAGATGGCG
AAGCTACTGGCGGCAGCAGGGCAGGCTGTTCCTGAAGTGAAGTACATTTTTGAGATCAACCCAAATCATACGCTTGTTAA
GCAAATGGCGGATGAGACGGATGAAGAAGCGTTTGGCCGCTGGGTAGAGGTATTACTGGGTCAAGCAATGCTTGCAGAGC
GTGGCTCAATGGAAGATCCTAGCCAGTTCTTAACGGCCATTAACTCGCTTTTGACTAAGGGCTAA

Upstream 100 bases:

>100_bases
AGCGTTTTTACCACAATTGACCTTGAATTTACATTTGTCAGCCATATGTTACGTAACAAGCGATTGATTTCCCACCCAAT
TAGAGAACTTTGGAGTGAAA

Downstream 100 bases:

>100_bases
TAAGGCTAAAATCACCAAAAAGCTCGCATTTGCGGGCTTTTTGTATGTATCGGCATTCAACATGCAAAAAAATGATGGTT
TCCAAAGCGATTTGTGAGAG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MNETVANNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNPALYENDAELGVKLSFNEEHNT
LTISDNGIGMSREEVISHLGTIAKSGTAEFFSKLSQEQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGLSADQAVLWH
SAGEGEYTVEDITKESRGTDIILHMREDGKEFLNEWRLRDVIGKYSDHIGIPVSIQTRVRDEEGKETEEVKWEQINKAQA
LWTRNKSDISDEEYQEFYKHVSHDFADPLLWSHNRVEGKNDYTSLLYIPSKAPWDMMNRDHKSGLKLYVQRVFIMDDAEQ
FMPSYLRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGACTKRVLTMLERLAKNDTDKYQTFWKEFGLVMKEGPAEDYAN
REKVASLLRFASTEVDSAEQTVSLESYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGLEVILMFDRIDEWLMNYL
TEFDGKQFQSITKAGLDLSQFEDEQEKEKQKETEQEFQSVVERTKSYLGDRVKEVRTTFKLANTPAVVVTDDFEMGTQMA
KLLAAAGQAVPEVKYIFEINPNHTLVKQMADETDEEAFGRWVEVLLGQAMLAERGSMEDPSQFLTAINSLLTKG

Sequences:

>Translated_634_residues
MNETVANNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNPALYENDAELGVKLSFNEEHNT
LTISDNGIGMSREEVISHLGTIAKSGTAEFFSKLSQEQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGLSADQAVLWH
SAGEGEYTVEDITKESRGTDIILHMREDGKEFLNEWRLRDVIGKYSDHIGIPVSIQTRVRDEEGKETEEVKWEQINKAQA
LWTRNKSDISDEEYQEFYKHVSHDFADPLLWSHNRVEGKNDYTSLLYIPSKAPWDMMNRDHKSGLKLYVQRVFIMDDAEQ
FMPSYLRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGACTKRVLTMLERLAKNDTDKYQTFWKEFGLVMKEGPAEDYAN
REKVASLLRFASTEVDSAEQTVSLESYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGLEVILMFDRIDEWLMNYL
TEFDGKQFQSITKAGLDLSQFEDEQEKEKQKETEQEFQSVVERTKSYLGDRVKEVRTTFKLANTPAVVVTDDFEMGTQMA
KLLAAAGQAVPEVKYIFEINPNHTLVKQMADETDEEAFGRWVEVLLGQAMLAERGSMEDPSQFLTAINSLLTKG
>Mature_634_residues
MNETVANNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNPALYENDAELGVKLSFNEEHNT
LTISDNGIGMSREEVISHLGTIAKSGTAEFFSKLSQEQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGLSADQAVLWH
SAGEGEYTVEDITKESRGTDIILHMREDGKEFLNEWRLRDVIGKYSDHIGIPVSIQTRVRDEEGKETEEVKWEQINKAQA
LWTRNKSDISDEEYQEFYKHVSHDFADPLLWSHNRVEGKNDYTSLLYIPSKAPWDMMNRDHKSGLKLYVQRVFIMDDAEQ
FMPSYLRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGACTKRVLTMLERLAKNDTDKYQTFWKEFGLVMKEGPAEDYAN
REKVASLLRFASTEVDSAEQTVSLESYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGLEVILMFDRIDEWLMNYL
TEFDGKQFQSITKAGLDLSQFEDEQEKEKQKETEQEFQSVVERTKSYLGDRVKEVRTTFKLANTPAVVVTDDFEMGTQMA
KLLAAAGQAVPEVKYIFEINPNHTLVKQMADETDEEAFGRWVEVLLGQAMLAERGSMEDPSQFLTAINSLLTKG

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI153792590, Length=691, Percent_Identity=37.4819102749638, Blast_Score=425, Evalue=1e-119,
Organism=Homo sapiens, GI20149594, Length=687, Percent_Identity=36.9723435225619, Blast_Score=415, Evalue=1e-116,
Organism=Homo sapiens, GI4507677, Length=634, Percent_Identity=37.0662460567823, Blast_Score=406, Evalue=1e-113,
Organism=Homo sapiens, GI155722983, Length=647, Percent_Identity=34.9304482225657, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI154146191, Length=417, Percent_Identity=37.1702637889688, Blast_Score=261, Evalue=2e-69,
Organism=Escherichia coli, GI1786679, Length=624, Percent_Identity=70.6730769230769, Blast_Score=926, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=678, Percent_Identity=37.0206489675516, Blast_Score=449, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17542208, Length=673, Percent_Identity=36.1069836552749, Blast_Score=399, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI115535205, Length=646, Percent_Identity=32.9721362229102, Blast_Score=317, Evalue=9e-87,
Organism=Caenorhabditis elegans, GI115535167, Length=436, Percent_Identity=35.5504587155963, Blast_Score=257, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6323840, Length=681, Percent_Identity=37.8854625550661, Blast_Score=442, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6325016, Length=687, Percent_Identity=37.2634643377001, Blast_Score=438, Evalue=1e-123,
Organism=Drosophila melanogaster, GI17647529, Length=685, Percent_Identity=37.8102189781022, Blast_Score=459, Evalue=1e-129,
Organism=Drosophila melanogaster, GI21357739, Length=696, Percent_Identity=36.6379310344828, Blast_Score=408, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24586016, Length=651, Percent_Identity=33.1797235023041, Blast_Score=364, Evalue=1e-101,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_VIBVU (Q8DFM0)

Other databases:

- EMBL:   AE016795
- RefSeq:   NP_759199.1
- ProteinModelPortal:   Q8DFM0
- SMR:   Q8DFM0
- GeneID:   1177141
- GenomeReviews:   AE016795_GR
- KEGG:   vvu:VV1_0189
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- BioCyc:   VVUL216895:VV1_0189-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 72345; Mature: 72345

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETVANNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNPA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCC
LYENDAELGVKLSFNEEHNTLTISDNGIGMSREEVISHLGTIAKSGTAEFFSKLSQEQSK
CCCCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DSQLIGQFGVGFYSAFIVADAVTVRTRAAGLSADQAVLWHSAGEGEYTVEDITKESRGTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEHHHHHHHCCCCE
IILHMREDGKEFLNEWRLRDVIGKYSDHIGIPVSIQTRVRDEEGKETEEVKWEQINKAQA
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHCCCCCCCCCHHHHHHHHHHHHHH
LWTRNKSDISDEEYQEFYKHVSHDFADPLLWSHNRVEGKNDYTSLLYIPSKAPWDMMNRD
HHCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEEECCCCCHHHHCCC
HKSGLKLYVQRVFIMDDAEQFMPSYLRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGAC
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
TKRVLTMLERLAKNDTDKYQTFWKEFGLVMKEGPAEDYANREKVASLLRFASTEVDSAEQ
HHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCCCCHHHCCHHHHHHHHHHHHCCCCCHHH
TVSLESYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGLEVILMFDRIDEWLMNYL
HHHHHHHHHHHHCCCCEEEEEECCCHHHCCCCCCHHHHHHCCCEEEEHHHHHHHHHHHHH
TEFDGKQFQSITKAGLDLSQFEDEQEKEKQKETEQEFQSVVERTKSYLGDRVKEVRTTFK
HHCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANTPAVVVTDDFEMGTQMAKLLAAAGQAVPEVKYIFEINPNHTLVKQMADETDEEAFGR
CCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHCCCCHHHHHH
WVEVLLGQAMLAERGSMEDPSQFLTAINSLLTKG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNETVANNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNPA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCC
LYENDAELGVKLSFNEEHNTLTISDNGIGMSREEVISHLGTIAKSGTAEFFSKLSQEQSK
CCCCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DSQLIGQFGVGFYSAFIVADAVTVRTRAAGLSADQAVLWHSAGEGEYTVEDITKESRGTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEHHHHHHHCCCCE
IILHMREDGKEFLNEWRLRDVIGKYSDHIGIPVSIQTRVRDEEGKETEEVKWEQINKAQA
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHCCCCCCCCCHHHHHHHHHHHHHH
LWTRNKSDISDEEYQEFYKHVSHDFADPLLWSHNRVEGKNDYTSLLYIPSKAPWDMMNRD
HHCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEEECCCCCHHHHCCC
HKSGLKLYVQRVFIMDDAEQFMPSYLRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGAC
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
TKRVLTMLERLAKNDTDKYQTFWKEFGLVMKEGPAEDYANREKVASLLRFASTEVDSAEQ
HHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCCCCHHHCCHHHHHHHHHHHHCCCCCHHH
TVSLESYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGLEVILMFDRIDEWLMNYL
HHHHHHHHHHHHCCCCEEEEEECCCHHHCCCCCCHHHHHHCCCEEEEHHHHHHHHHHHHH
TEFDGKQFQSITKAGLDLSQFEDEQEKEKQKETEQEFQSVVERTKSYLGDRVKEVRTTFK
HHCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LANTPAVVVTDDFEMGTQMAKLLAAAGQAVPEVKYIFEINPNHTLVKQMADETDEEAFGR
CCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHCCCCHHHHHH
WVEVLLGQAMLAERGSMEDPSQFLTAINSLLTKG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA