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The map label for this gene is ygbD [C]

Identifier: 27363648

GI number: 27363648

Start: 154758

End: 156080

Strand: Reverse

Name: ygbD [C]

Synonym: VV1_0165

Alternate gene names: 27363648

Gene position: 156080-154758 (Counterclockwise)

Preceding gene: 27363649

Following gene: 27363646

Centisome position: 4.76

GC content: 48.98

Gene sequence:

>1323_bases
ATGAAAGTTGTTGTCGTAGGCGGTAGCGCCGCTGGGATGAGTTTTGCTGCAAAGTACAAGCGTAATCAGCCGTCGGATGA
AGTGATTGTGCTGGATAAGCGAGATTACATCTCATTTGGTGCGTGTGGCTTACCTTACTTTGCTGGTGGCATGTTTGATG
ACACCGAGCGTATGATTTCTCGTACGCCAGAACAGGCGATTAAATCTGGCTTGGATGTGCGCATTGAAACCGAAATGGTG
GCTTTAGAGCGCATTGAAAAGCAGATCACGGTTCGTCATCAAGGTGAAGAAACCATTTTAGATTACGATATGCTGGTGAT
TGCCACTGGTGCTCGTCCAATCATCCCTTCCTTTGGTGAGTTCAACCCAGAGCACGTATACACGTTAACCAGCATGGAAG
ATGGCTTGGCAGTAAAACAAGCGCTTAAGGACAGCAACAAACAACGCGTTTGCGTGATTGGCGGTGGTTTTATCGGTCTT
GAAGTGTTTGATGCCGCGCACTTACTAGGTAAGCATGTCACCATCATTGAACGCGAGCAACATGTCATGAGTCGTCAATT
CAGCCCTGAAATGATCGACGTTGTGGAAGGCGCGATTCGCGAATCTGGCGCTGAGCTTAAAACCAGTTGCAGCGTATCGG
CCATTCGCGATGCAGAGCAGGGCGGTTATCTTGTCGAAACCGACAACGGCAGCGTCGCGGCAGACGTGGTGATTATGTCC
CTGGGCTTCAAACCAAACACAGAAGCGTTCGAGTTACCAAAAGCGGCTAACGGCGCATTGCTTGTCGACGAGTTTGGTGC
AACAGAAGATGAGCATATCTACGCGGTTGGTGACTGTGCGGTGGTTCATCATATGGCGCTAGGCAAAACGGTTTATGTTC
CTCTAGCGACGACAGCCAACAAACAAGCGCGCATGATGGCGGATAAGCTTGCAGGCAAAGACACTTACATGAATGGTTTC
CTAGGCTCATCTTGTTTAAAAGTGTTGGACTACGAACTCGCATGCACTGGCGTATCTGAACTGCTCGCCAAAGAGCATGG
CTTAGATGTGAGGGTTTCCACCATTTCAGATAAGAACCAAACCGATTACTACCCAGGCCAAGAAGATATCAAAGTGAAGT
TGGTTTACCACCCAGAGACTAAGGTTCTACTTGGCGGTGAGATTGTTGGTAAAAAAGGTGCTGTGGGTCGAATCAACGCG
CTAGCGGTTGCGATTACGGCCAAAATGACCACACAACAGCTAGGTTACATGGACTTTTGCTACGCGCCGCCATTTGCACG
CACATGGGATGCATTAAATGTGGCTGGCAATGTCGCGAAATAA

Upstream 100 bases:

>100_bases
AGCGACCAAAGAAGCGGCGGTGTAATGTGTAAACGAAATGGAGAGCACCCATAAGGGTGCTCTTCGGTTTTCCTAAGTTC
AGTTTATTTAGGTAGTAAAT

Downstream 100 bases:

>100_bases
TGGCACAGTACGAAGGGAAGCGATGCTTCCCTTTTTTACATTCCATTATGTGGCCAGTTATCCGGCACGATAAACCAGAA
TTGGCCACTTTTACTTTGTG

Product: coenzyme A disulfide reductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKVVVVGGSAAGMSFAAKYKRNQPSDEVIVLDKRDYISFGACGLPYFAGGMFDDTERMISRTPEQAIKSGLDVRIETEMV
ALERIEKQITVRHQGEETILDYDMLVIATGARPIIPSFGEFNPEHVYTLTSMEDGLAVKQALKDSNKQRVCVIGGGFIGL
EVFDAAHLLGKHVTIIEREQHVMSRQFSPEMIDVVEGAIRESGAELKTSCSVSAIRDAEQGGYLVETDNGSVAADVVIMS
LGFKPNTEAFELPKAANGALLVDEFGATEDEHIYAVGDCAVVHHMALGKTVYVPLATTANKQARMMADKLAGKDTYMNGF
LGSSCLKVLDYELACTGVSELLAKEHGLDVRVSTISDKNQTDYYPGQEDIKVKLVYHPETKVLLGGEIVGKKGAVGRINA
LAVAITAKMTTQQLGYMDFCYAPPFARTWDALNVAGNVAK

Sequences:

>Translated_440_residues
MKVVVVGGSAAGMSFAAKYKRNQPSDEVIVLDKRDYISFGACGLPYFAGGMFDDTERMISRTPEQAIKSGLDVRIETEMV
ALERIEKQITVRHQGEETILDYDMLVIATGARPIIPSFGEFNPEHVYTLTSMEDGLAVKQALKDSNKQRVCVIGGGFIGL
EVFDAAHLLGKHVTIIEREQHVMSRQFSPEMIDVVEGAIRESGAELKTSCSVSAIRDAEQGGYLVETDNGSVAADVVIMS
LGFKPNTEAFELPKAANGALLVDEFGATEDEHIYAVGDCAVVHHMALGKTVYVPLATTANKQARMMADKLAGKDTYMNGF
LGSSCLKVLDYELACTGVSELLAKEHGLDVRVSTISDKNQTDYYPGQEDIKVKLVYHPETKVLLGGEIVGKKGAVGRINA
LAVAITAKMTTQQLGYMDFCYAPPFARTWDALNVAGNVAK
>Mature_440_residues
MKVVVVGGSAAGMSFAAKYKRNQPSDEVIVLDKRDYISFGACGLPYFAGGMFDDTERMISRTPEQAIKSGLDVRIETEMV
ALERIEKQITVRHQGEETILDYDMLVIATGARPIIPSFGEFNPEHVYTLTSMEDGLAVKQALKDSNKQRVCVIGGGFIGL
EVFDAAHLLGKHVTIIEREQHVMSRQFSPEMIDVVEGAIRESGAELKTSCSVSAIRDAEQGGYLVETDNGSVAADVVIMS
LGFKPNTEAFELPKAANGALLVDEFGATEDEHIYAVGDCAVVHHMALGKTVYVPLATTANKQARMMADKLAGKDTYMNGF
LGSSCLKVLDYELACTGVSELLAKEHGLDVRVSTISDKNQTDYYPGQEDIKVKLVYHPETKVLLGGEIVGKKGAVGRINA
LAVAITAKMTTQQLGYMDFCYAPPFARTWDALNVAGNVAK

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI22035672, Length=258, Percent_Identity=25.968992248062, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI226437568, Length=326, Percent_Identity=23.9263803680982, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI65787454, Length=326, Percent_Identity=23.9263803680982, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI21389617, Length=326, Percent_Identity=23.9263803680982, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789065, Length=217, Percent_Identity=27.6497695852535, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786307, Length=317, Percent_Identity=26.4984227129338, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789915, Length=182, Percent_Identity=30.2197802197802, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789765, Length=345, Percent_Identity=24.6376811594203, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 47694; Mature: 47694

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVVVGGSAAGMSFAAKYKRNQPSDEVIVLDKRDYISFGACGLPYFAGGMFDDTERMIS
CEEEEECCCCCCCHHHHHHHCCCCCCCEEEEECCCCEEECCCCCHHHCCCCCCHHHHHHH
RTPEQAIKSGLDVRIETEMVALERIEKQITVRHQGEETILDYDMLVIATGARPIIPSFGE
CCHHHHHHCCCCEEEEHHHHHHHHHHHHEEEEECCCCEEEEEEEEEEEECCCCCCCCCCC
FNPEHVYTLTSMEDGLAVKQALKDSNKQRVCVIGGGFIGLEVFDAAHLLGKHVTIIEREQ
CCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEEECCEEEHHHHHHHHHHCCCEEEEEHHH
HVMSRQFSPEMIDVVEGAIRESGAELKTSCSVSAIRDAEQGGYLVETDNGSVAADVVIMS
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEECCCCCEEEEEEEEE
LGFKPNTEAFELPKAANGALLVDEFGATEDEHIYAVGDCAVVHHMALGKTVYVPLATTAN
ECCCCCCCCEECCCCCCCCEEEECCCCCCCCEEEEEECHHHHHHHHCCCEEEEEEECCCC
KQARMMADKLAGKDTYMNGFLGSSCLKVLDYELACTGVSELLAKEHGLDVRVSTISDKNQ
HHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCC
TDYYPGQEDIKVKLVYHPETKVLLGGEIVGKKGAVGRINALAVAITAKMTTQQLGYMDFC
CCCCCCCCCEEEEEEECCCCEEEECCEEECCCCCCCEEEEEEEEEEEHHHHHHCCCEEEE
YAPPFARTWDALNVAGNVAK
CCCCCHHHCCHHHCCCCCCC
>Mature Secondary Structure
MKVVVVGGSAAGMSFAAKYKRNQPSDEVIVLDKRDYISFGACGLPYFAGGMFDDTERMIS
CEEEEECCCCCCCHHHHHHHCCCCCCCEEEEECCCCEEECCCCCHHHCCCCCCHHHHHHH
RTPEQAIKSGLDVRIETEMVALERIEKQITVRHQGEETILDYDMLVIATGARPIIPSFGE
CCHHHHHHCCCCEEEEHHHHHHHHHHHHEEEEECCCCEEEEEEEEEEEECCCCCCCCCCC
FNPEHVYTLTSMEDGLAVKQALKDSNKQRVCVIGGGFIGLEVFDAAHLLGKHVTIIEREQ
CCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEEECCEEEHHHHHHHHHHCCCEEEEEHHH
HVMSRQFSPEMIDVVEGAIRESGAELKTSCSVSAIRDAEQGGYLVETDNGSVAADVVIMS
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEECCCCCEEEEEEEEE
LGFKPNTEAFELPKAANGALLVDEFGATEDEHIYAVGDCAVVHHMALGKTVYVPLATTAN
ECCCCCCCCEECCCCCCCCEEEECCCCCCCCEEEEEECHHHHHHHHCCCEEEEEEECCCC
KQARMMADKLAGKDTYMNGFLGSSCLKVLDYELACTGVSELLAKEHGLDVRVSTISDKNQ
HHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCC
TDYYPGQEDIKVKLVYHPETKVLLGGEIVGKKGAVGRINALAVAITAKMTTQQLGYMDFC
CCCCCCCCCEEEEEEECCCCEEEECCEEECCCCCCCEEEEEEEEEEEHHHHHHCCCEEEE
YAPPFARTWDALNVAGNVAK
CCCCCHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA