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The map label for this gene is trpB [H]

Identifier: 23502958

GI number: 23502958

Start: 2035202

End: 2036422

Strand: Reverse

Name: trpB [H]

Synonym: BR2110

Alternate gene names: 23502958

Gene position: 2036422-2035202 (Counterclockwise)

Preceding gene: 23502959

Following gene: 23502957

Centisome position: 96.61

GC content: 59.95

Gene sequence:

>1221_bases
TTGAACAAGCCGGTTGCACCCAATTCCTACAAGACGGGCCCTGACGAAGAGGGCATGTTCGGCATATTCGGTGGCCGCTT
CGTCGCCGAAACGCTGATGCCTCTGATCCTCGAATTGCAGCAGGCTTATGAAACGGCGAAGAATGACCCCGAATTCAAGG
CGGAGTTGAACGCCCTTTCCACCTTTTATGCCGGCCGTCCTTCCAAGCTCTATTATGCCGAAGGCCTGAGCAAACATCTG
GGTGGCGCTAAAATCTACTTCAAGCGCGAAGACCTGAACCATACCGGCAGCCACAAAATCAACAATTGCCTTGGCCAGAT
CCTGCTTGCCAAGCGCATGGGCAAGACGCGCATCATCGCAGAAACGGGCGCCGGTCAGCATGGCGTGGCGTCTGCCACCG
TTGCCGCACGCTTCGGCCTGCCCTGTATCGTCTATATGGGCGCAACCGACGTGGAGCGCCAGAAGCCCAATGTTTTCCGC
ATGAAGCTGCTCGGCGCGGAAGTGAAGCCGGTTTCTGCCGGCAATGGCACGCTGAAAGACGCGATGAACGAAGCCCTGCG
TGACTGGGTTACGAATGTCGAGGATACCTATTACCTGATCGGCACGGCTGCCGGTCCGCACCCCTATCCCGAACTGGTGC
GCGATTTCCAATCCGTCATCGGCACCGAAGCGCGCCAGCAGATACTCGAACAGGAAGGCCGCCTGCCAGATGTGATCGTG
GCAGCGGTCGGCGGCGGCTCCAACGCCATTGGCCTGTTCCATCCGTTCCTCGACGACGCCTCGGTGAAGATCGTCGGTGT
CGAAGCAGGCGGACGCGGTCTTGAGGGAGAGGAACATTGCGCTTCGATGAGCGCAGGCCGCCCCGGCGTTCTGCATGGCA
ACCGCACCTATCTCCTCCAGAACGCGGATGGCCAAATTCTGGAAGGCCATTCGGTTTCCGCTGGTCTCGACTATCCGGGC
GTCGGGCCCGAGCATTCGTGGCTGAAGGACAGCGGGCGCGTCGACTATGTGCCGATCCTCGACAATGAGGCGCTGGATGC
ATTCCAGCTTTGCACCCGCACCGAAGGCATCATCCCGGCGCTCGAATCCGCCCATGCCATTGCGCAGGCCGTCAAAATGG
CGCCGACAATGGGCAAGGACAAGGTGATGATCGTCAATCTGTCCGGCCGCGGCGACAAGGACGTCCACACGGTCGGCAAG
CTTCTCGGCATGGATATCTGA

Upstream 100 bases:

>100_bases
GAAAAGGACGTGCGTCTTATTGAGAATTTTTTCCAGGCCGTAGCGGATGCGAATGCTCAGCCATTCGCCAGGCGCGCCTG
AACATGACGGAGCGGAAACG

Downstream 100 bases:

>100_bases
CAATGAGCACCGCCCCCGCCACCTCCTGCTACAAGCCGCGCGCCGCATGGTTCGACGGCCTGACGGAGTGTGGCCCGGCG
GCAATCAAGCTCAGCATTAT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MNKPVAPNSYKTGPDEEGMFGIFGGRFVAETLMPLILELQQAYETAKNDPEFKAELNALSTFYAGRPSKLYYAEGLSKHL
GGAKIYFKREDLNHTGSHKINNCLGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCIVYMGATDVERQKPNVFR
MKLLGAEVKPVSAGNGTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPELVRDFQSVIGTEARQQILEQEGRLPDVIV
AAVGGGSNAIGLFHPFLDDASVKIVGVEAGGRGLEGEEHCASMSAGRPGVLHGNRTYLLQNADGQILEGHSVSAGLDYPG
VGPEHSWLKDSGRVDYVPILDNEALDAFQLCTRTEGIIPALESAHAIAQAVKMAPTMGKDKVMIVNLSGRGDKDVHTVGK
LLGMDI

Sequences:

>Translated_406_residues
MNKPVAPNSYKTGPDEEGMFGIFGGRFVAETLMPLILELQQAYETAKNDPEFKAELNALSTFYAGRPSKLYYAEGLSKHL
GGAKIYFKREDLNHTGSHKINNCLGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCIVYMGATDVERQKPNVFR
MKLLGAEVKPVSAGNGTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPELVRDFQSVIGTEARQQILEQEGRLPDVIV
AAVGGGSNAIGLFHPFLDDASVKIVGVEAGGRGLEGEEHCASMSAGRPGVLHGNRTYLLQNADGQILEGHSVSAGLDYPG
VGPEHSWLKDSGRVDYVPILDNEALDAFQLCTRTEGIIPALESAHAIAQAVKMAPTMGKDKVMIVNLSGRGDKDVHTVGK
LLGMDI
>Mature_406_residues
MNKPVAPNSYKTGPDEEGMFGIFGGRFVAETLMPLILELQQAYETAKNDPEFKAELNALSTFYAGRPSKLYYAEGLSKHL
GGAKIYFKREDLNHTGSHKINNCLGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCIVYMGATDVERQKPNVFR
MKLLGAEVKPVSAGNGTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPELVRDFQSVIGTEARQQILEQEGRLPDVIV
AAVGGGSNAIGLFHPFLDDASVKIVGVEAGGRGLEGEEHCASMSAGRPGVLHGNRTYLLQNADGQILEGHSVSAGLDYPG
VGPEHSWLKDSGRVDYVPILDNEALDAFQLCTRTEGIIPALESAHAIAQAVKMAPTMGKDKVMIVNLSGRGDKDVHTVGK
LLGMDI

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=384, Percent_Identity=56.5104166666667, Blast_Score=449, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=56.5104166666667, Blast_Score=458, Evalue=1e-130,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43571; Mature: 43571

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPVAPNSYKTGPDEEGMFGIFGGRFVAETLMPLILELQQAYETAKNDPEFKAELNALS
CCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
TFYAGRPSKLYYAEGLSKHLGGAKIYFKREDLNHTGSHKINNCLGQILLAKRMGKTRIIA
HHHCCCCCEEEHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEE
ETGAGQHGVASATVAARFGLPCIVYMGATDVERQKPNVFRMKLLGAEVKPVSAGNGTLKD
ECCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHCCCCEEEEEEECCCCCCCCCCCCHHHH
AMNEALRDWVTNVEDTYYLIGTAAGPHPYPELVRDFQSVIGTEARQQILEQEGRLPDVIV
HHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEE
AAVGGGSNAIGLFHPFLDDASVKIVGVEAGGRGLEGEEHCASMSAGRPGVLHGNRTYLLQ
EEECCCCCCEEEEHHCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCEEECCEEEEEE
NADGQILEGHSVSAGLDYPGVGPEHSWLKDSGRVDYVPILDNEALDAFQLCTRTEGIIPA
CCCCCEEECCCCCCCCCCCCCCCCCCHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCHH
LESAHAIAQAVKMAPTMGKDKVMIVNLSGRGDKDVHTVGKLLGMDI
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNKPVAPNSYKTGPDEEGMFGIFGGRFVAETLMPLILELQQAYETAKNDPEFKAELNALS
CCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
TFYAGRPSKLYYAEGLSKHLGGAKIYFKREDLNHTGSHKINNCLGQILLAKRMGKTRIIA
HHHCCCCCEEEHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEE
ETGAGQHGVASATVAARFGLPCIVYMGATDVERQKPNVFRMKLLGAEVKPVSAGNGTLKD
ECCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHCCCCEEEEEEECCCCCCCCCCCCHHHH
AMNEALRDWVTNVEDTYYLIGTAAGPHPYPELVRDFQSVIGTEARQQILEQEGRLPDVIV
HHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEE
AAVGGGSNAIGLFHPFLDDASVKIVGVEAGGRGLEGEEHCASMSAGRPGVLHGNRTYLLQ
EEECCCCCCEEEEHHCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCEEECCEEEEEE
NADGQILEGHSVSAGLDYPGVGPEHSWLKDSGRVDYVPILDNEALDAFQLCTRTEGIIPA
CCCCCEEECCCCCCCCCCCCCCCCCCHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCHH
LESAHAIAQAVKMAPTMGKDKVMIVNLSGRGDKDVHTVGKLLGMDI
HHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA