Click here to switch to the map view.

The map label for this gene is accD [H]

Identifier: 23502955

GI number: 23502955

Start: 2032930

End: 2033835

Strand: Reverse

Name: accD [H]

Synonym: BR2107

Alternate gene names: 23502955

Gene position: 2033835-2032930 (Counterclockwise)

Preceding gene: 23502956

Following gene: 23502954

Centisome position: 96.49

GC content: 57.17

Gene sequence:

>906_bases
ATGAACTGGATCACCAACTACGTTCGTCCGAAGATCAATTCGATGCTCGGCCGCCGTGAAATGCCGGAAAATCTATGGAT
CAAGGATCCATCGACCGGCGAAATGGTGTTCCACAAGGATCTGGAAAGCAACCAGTTCGTGATTCCGTCTTCGGGCCATC
ACATGCGCATCAAGGCGAAGGATCGCCTGCGCTTTTTCTTCGACAATGGCGAATATACGACGCTTGAAGCGCCGAAAGTG
CCGCTCGATCCACTGAAATTTCGCGACGAGAAGAAATATATCGATCGCCTCAAGGATTATCGCAGCCGCACCGGCATGGA
TGACGCCATTGTCAACGGCCTCGGCACCATCGAGGGCCTGCCAATCGTTGCAACCGTGCAGGATTTCAGCTTCATGGGCG
GTTCGCTCGGCATGGGCGCTGGCGAAGCCATCATCCAGGGCTTTGAAAAAGCCATCGAACTGAAGCGCCCGCTCGTGCTG
TTCGCCTCTTCCGGCGGTGCGCGTATGCAGGAAGGCATTCTCTCGCTGATGCAGCTTCCGCGCACGACCGTTGCTGTCGA
AATGCTGAAAGAAGCAGGCCTGCCCTATATCGTTGTGCTGACCAACCCGACGACCGGCGGCGTCACCGCTTCCTATGCCA
TGCTGGGCGATATCCACATTGCCGAACCCGGCGCGCTCATCGGCTTTGCCGGCCCGCGCGTGATCGAACAGACCATCCGC
GAAAAGCTTCCTGAAGGCTTCCAGAGCTCCGAATATCTCATGGAGCACGGCATGGTGGATATGGTCGTTTCCCGCCTTGA
ACTGAAGGCAACGATTGCACGGCTTCTCAAGATCATGACGAAGCAGCCTGCCAACAGCGATGCACCCGCCCCCCAGAAGC
CGGATGCTGACAGCAAGGCAGCCTGA

Upstream 100 bases:

>100_bases
AGAGAGTGTGCGCGCCACACGCCTTGAAGCCGCCCAATAAATCGTCCATTTAAGCGGCTGAGAAGTCGTTGCCGAAGAAC
AAGAAACGGAACCAAACGTC

Downstream 100 bases:

>100_bases
TCGTGACAGGAAAAGCCGCCGCCGCAATCGAGCGGCTTATGCAGTTGCATCCCAAGGGCTTCGATCTTTCGCTGGACCGC
ATTCGCGGCCTTCTGGAAAA

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNWITNYVRPKINSMLGRREMPENLWIKDPSTGEMVFHKDLESNQFVIPSSGHHMRIKAKDRLRFFFDNGEYTTLEAPKV
PLDPLKFRDEKKYIDRLKDYRSRTGMDDAIVNGLGTIEGLPIVATVQDFSFMGGSLGMGAGEAIIQGFEKAIELKRPLVL
FASSGGARMQEGILSLMQLPRTTVAVEMLKEAGLPYIVVLTNPTTGGVTASYAMLGDIHIAEPGALIGFAGPRVIEQTIR
EKLPEGFQSSEYLMEHGMVDMVVSRLELKATIARLLKIMTKQPANSDAPAPQKPDADSKAA

Sequences:

>Translated_301_residues
MNWITNYVRPKINSMLGRREMPENLWIKDPSTGEMVFHKDLESNQFVIPSSGHHMRIKAKDRLRFFFDNGEYTTLEAPKV
PLDPLKFRDEKKYIDRLKDYRSRTGMDDAIVNGLGTIEGLPIVATVQDFSFMGGSLGMGAGEAIIQGFEKAIELKRPLVL
FASSGGARMQEGILSLMQLPRTTVAVEMLKEAGLPYIVVLTNPTTGGVTASYAMLGDIHIAEPGALIGFAGPRVIEQTIR
EKLPEGFQSSEYLMEHGMVDMVVSRLELKATIARLLKIMTKQPANSDAPAPQKPDADSKAA
>Mature_301_residues
MNWITNYVRPKINSMLGRREMPENLWIKDPSTGEMVFHKDLESNQFVIPSSGHHMRIKAKDRLRFFFDNGEYTTLEAPKV
PLDPLKFRDEKKYIDRLKDYRSRTGMDDAIVNGLGTIEGLPIVATVQDFSFMGGSLGMGAGEAIIQGFEKAIELKRPLVL
FASSGGARMQEGILSLMQLPRTTVAVEMLKEAGLPYIVVLTNPTTGGVTASYAMLGDIHIAEPGALIGFAGPRVIEQTIR
EKLPEGFQSSEYLMEHGMVDMVVSRLELKATIARLLKIMTKQPANSDAPAPQKPDADSKAA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=200, Percent_Identity=26, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788655, Length=307, Percent_Identity=48.2084690553746, Blast_Score=285, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 33270; Mature: 33270

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS01159 WW_DOMAIN_1 ; PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWITNYVRPKINSMLGRREMPENLWIKDPSTGEMVFHKDLESNQFVIPSSGHHMRIKAK
CCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEECCCCCEEEECCCCCEEEEEEC
DRLRFFFDNGEYTTLEAPKVPLDPLKFRDEKKYIDRLKDYRSRTGMDDAIVNGLGTIEGL
CCEEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
PIVATVQDFSFMGGSLGMGAGEAIIQGFEKAIELKRPLVLFASSGGARMQEGILSLMQLP
CEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCC
RTTVAVEMLKEAGLPYIVVLTNPTTGGVTASYAMLGDIHIAEPGALIGFAGPRVIEQTIR
HHHHHHHHHHHCCCCEEEEEECCCCCCCEEHHHHCCCEEEECCCCEEECCCHHHHHHHHH
EKLPEGFQSSEYLMEHGMVDMVVSRLELKATIARLLKIMTKQPANSDAPAPQKPDADSKA
HHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
A
C
>Mature Secondary Structure
MNWITNYVRPKINSMLGRREMPENLWIKDPSTGEMVFHKDLESNQFVIPSSGHHMRIKAK
CCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEECCCCCEEEECCCCCEEEEEEC
DRLRFFFDNGEYTTLEAPKVPLDPLKFRDEKKYIDRLKDYRSRTGMDDAIVNGLGTIEGL
CCEEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
PIVATVQDFSFMGGSLGMGAGEAIIQGFEKAIELKRPLVLFASSGGARMQEGILSLMQLP
CEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCC
RTTVAVEMLKEAGLPYIVVLTNPTTGGVTASYAMLGDIHIAEPGALIGFAGPRVIEQTIR
HHHHHHHHHHHCCCCEEEEEECCCCCCCEEHHHHCCCEEEECCCCEEECCCHHHHHHHHH
EKLPEGFQSSEYLMEHGMVDMVVSRLELKATIARLLKIMTKQPANSDAPAPQKPDADSKA
HHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA