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The map label for this gene is ppa

Identifier: 23502841

GI number: 23502841

Start: 1919867

End: 1920397

Strand: Reverse

Name: ppa

Synonym: BR1993

Alternate gene names: 23502841

Gene position: 1920397-1919867 (Counterclockwise)

Preceding gene: 23502842

Following gene: 23502838

Centisome position: 91.11

GC content: 55.18

Gene sequence:

>531_bases
ATGAATATTGATGCCATCTCCATCGGCTCCAATCCTCCTGAAGACGTCAACGTAATCATTGAAGTGCCTGTCGGCGGCCA
GCCGATCAAGTACGAGATGGACAAGAAGGCCGGCGCGCTTATCGTCGACCGTTTCCTTTACACACCCATGACCTATCCGG
GCAATTACGGCTTCGTGCCGCATACGCTTTCGGAAGATGGCGATCCGATCGACGTTCTGGTCTGCAACACGCGCCCGCTC
ATTCCGGGTTGCGTGATCAATGTGCGCCCGATCGGCGTTCTGGTCATGGAAGACAATTCGGGCAAGGACGAGAAGATTAT
CGCGGTGCCTTCGCCGCATCTTACGCGCCGCTATGAGAAGATCCACGACTATACCGATATGCCGGAGATCACGCTGAAGC
AGATTGCGCATTTCTTCGAGCACTACAAGGATCTGGAACCCGGCAAGTGGGTCAAGATCGGCGACTGGGGCGATGAAGAC
TATGCCCGCAAATTCATCGTGGAAGCTATCGAGCGCGCCAAGGGCAAGTAA

Upstream 100 bases:

>100_bases
CGTTGCGAGAACGACAATTCGCCGCGTTTTCTTGAACTTTCGTTTTTCTTGCACCCGAACCTGAAACCCGTTATCAGAGC
GCGACACGAAAGGACACATC

Downstream 100 bases:

>100_bases
GCGATTGTTTCCAGAGCGGTTCCTGTTTTAACAGAACCATCGGAACCGCTCTATCTCTTTGTTTTGCCGCATTTTCGAGC
ATCGATCTGAATGAATCAGA

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MNIDAISIGSNPPEDVNVIIEVPVGGQPIKYEMDKKAGALIVDRFLYTPMTYPGNYGFVPHTLSEDGDPIDVLVCNTRPL
IPGCVINVRPIGVLVMEDNSGKDEKIIAVPSPHLTRRYEKIHDYTDMPEITLKQIAHFFEHYKDLEPGKWVKIGDWGDED
YARKFIVEAIERAKGK

Sequences:

>Translated_176_residues
MNIDAISIGSNPPEDVNVIIEVPVGGQPIKYEMDKKAGALIVDRFLYTPMTYPGNYGFVPHTLSEDGDPIDVLVCNTRPL
IPGCVINVRPIGVLVMEDNSGKDEKIIAVPSPHLTRRYEKIHDYTDMPEITLKQIAHFFEHYKDLEPGKWVKIGDWGDED
YARKFIVEAIERAKGK
>Mature_176_residues
MNIDAISIGSNPPEDVNVIIEVPVGGQPIKYEMDKKAGALIVDRFLYTPMTYPGNYGFVPHTLSEDGDPIDVLVCNTRPL
IPGCVINVRPIGVLVMEDNSGKDEKIIAVPSPHLTRRYEKIHDYTDMPEITLKQIAHFFEHYKDLEPGKWVKIGDWGDED
YARKFIVEAIERAKGK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family

Homologues:

Organism=Escherichia coli, GI1790673, Length=176, Percent_Identity=53.9772727272727, Blast_Score=201, Evalue=2e-53,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): IPYR_BRUME (P65744)

Other databases:

- EMBL:   AE008917
- PIR:   AG3261
- RefSeq:   NP_538994.1
- ProteinModelPortal:   P65744
- SMR:   P65744
- GeneID:   1195788
- GenomeReviews:   AE008917_GR
- KEGG:   bme:BMEI0076
- HOGENOM:   HBG529150
- OMA:   EHFFEHY
- PhylomeDB:   P65744
- ProtClustDB:   PRK01250
- BioCyc:   BMEL224914:BMEI0076-MONOMER
- BRENDA:   3.6.1.1
- GO:   GO:0005737
- HAMAP:   MF_00209
- InterPro:   IPR008162
- Gene3D:   G3DSA:3.90.80.10
- PANTHER:   PTHR10286

Pfam domain/function: PF00719 Pyrophosphatase; SSF50324 Pyrophosphatase

EC number: =3.6.1.1

Molecular weight: Translated: 19822; Mature: 19822

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDAISIGSNPPEDVNVIIEVPVGGQPIKYEMDKKAGALIVDRFLYTPMTYPGNYGFVP
CCCEEEECCCCCCCCEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCC
HTLSEDGDPIDVLVCNTRPLIPGCVINVRPIGVLVMEDNSGKDEKIIAVPSPHLTRRYEK
CCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEEEEECCCCCCCEEEEECCCHHHHHHHH
IHDYTDMPEITLKQIAHFFEHYKDLEPGKWVKIGDWGDEDYARKFIVEAIERAKGK
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIDAISIGSNPPEDVNVIIEVPVGGQPIKYEMDKKAGALIVDRFLYTPMTYPGNYGFVP
CCCEEEECCCCCCCCEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCC
HTLSEDGDPIDVLVCNTRPLIPGCVINVRPIGVLVMEDNSGKDEKIIAVPSPHLTRRYEK
CCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEEEEECCCCCCCEEEEECCCHHHHHHHH
IHDYTDMPEITLKQIAHFFEHYKDLEPGKWVKIGDWGDEDYARKFIVEAIERAKGK
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688