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The map label for this gene is plsC [H]

Identifier: 23502842

GI number: 23502842

Start: 1920550

End: 1921332

Strand: Reverse

Name: plsC [H]

Synonym: BR1994

Alternate gene names: 23502842

Gene position: 1921332-1920550 (Counterclockwise)

Preceding gene: 23502843

Following gene: 23502841

Centisome position: 91.15

GC content: 58.75

Gene sequence:

>783_bases
ATGCTTCTTTATCTGCGCTCCATCCTGTTCAATGCGGCGTTCTATATCTGTACCCTGGTGCAGATGATCCTCTATACGCC
CTTTTATTTCATCCTGCCGCGCAAGAAGGCCTGGATCGTCCCGAAGCTTTGGGCGCGGGTCAATCTGTGGCTTCAGAAAC
ATATTGCCGGCACCGATTGTGTGGTCGAAGGGCTGGAGAACATACCGGAAGGGGCCTATATCTGTGCGCCCAAGCACCAG
TCGGCCTGGGACACCTATGCCTTTCTGCCTTATCTGGACGATCCGGTGCTGATCCTGAAGCGGGAGCTGATGCGCATTCC
GCTGTTCGGCTGGTATATTGCCAAGATGCAGATGATCCCGGTGGACCGCGGTTCACGGGTGAAGGCGCTGCATTCCATCA
CCAAGGGCGCGGAAAAGGCAATTGCCGAAGGCCGCCAGATCCTCATCTATCCCGAAGGCACCCGCCGTTCGCCGGGGGCG
CCGCCGCAATATAAATACGGCATCGTGCATCTTTATGAGGCGCTCAATCTGCCTGTCGTGCCGATTGCGCATAATGCCGG
GCTTTACTGGCCGCGCCGCAAGTTCCTGCGTTATCCCGGCACCATTCGCTCGCGCATCCTTCCGCCCATCCCGGCGGGGC
TGCCGAAGGAAGAATTCCTGCGTCGCCTGATCGAATCCACCGAAACGGTCTGCGACGAATTTCTCGTGGCTGCAAGCCGC
GACCCCAATCCGCCTCCCATGCCGCCAACCGCCGTTCAAAGGCTGAAGGAACTGGGCGTGTGA

Upstream 100 bases:

>100_bases
GCTGCAAAATGCTCTATCTCTTTGTTTTTACGCATTACCCAATGCAAAACCACTTCGCACTTTTGCTGGAAATGCTCTAG
CGGGGGCCCTCGCCAATACG

Downstream 100 bases:

>100_bases
TCCTTGCCGAAAGTTCATGAGCCGATCGCGGTCATCCGATCACGTTCAATTGCGTTGCGAGAACGACAATTCGCCGCGTT
TTCTTGAACTTTCGTTTTTC

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLLYLRSILFNAAFYICTLVQMILYTPFYFILPRKKAWIVPKLWARVNLWLQKHIAGTDCVVEGLENIPEGAYICAPKHQ
SAWDTYAFLPYLDDPVLILKRELMRIPLFGWYIAKMQMIPVDRGSRVKALHSITKGAEKAIAEGRQILIYPEGTRRSPGA
PPQYKYGIVHLYEALNLPVVPIAHNAGLYWPRRKFLRYPGTIRSRILPPIPAGLPKEEFLRRLIESTETVCDEFLVAASR
DPNPPPMPPTAVQRLKELGV

Sequences:

>Translated_260_residues
MLLYLRSILFNAAFYICTLVQMILYTPFYFILPRKKAWIVPKLWARVNLWLQKHIAGTDCVVEGLENIPEGAYICAPKHQ
SAWDTYAFLPYLDDPVLILKRELMRIPLFGWYIAKMQMIPVDRGSRVKALHSITKGAEKAIAEGRQILIYPEGTRRSPGA
PPQYKYGIVHLYEALNLPVVPIAHNAGLYWPRRKFLRYPGTIRSRILPPIPAGLPKEEFLRRLIESTETVCDEFLVAASR
DPNPPPMPPTAVQRLKELGV
>Mature_260_residues
MLLYLRSILFNAAFYICTLVQMILYTPFYFILPRKKAWIVPKLWARVNLWLQKHIAGTDCVVEGLENIPEGAYICAPKHQ
SAWDTYAFLPYLDDPVLILKRELMRIPLFGWYIAKMQMIPVDRGSRVKALHSITKGAEKAIAEGRQILIYPEGTRRSPGA
PPQYKYGIVHLYEALNLPVVPIAHNAGLYWPRRKFLRYPGTIRSRILPPIPAGLPKEEFLRRLIESTETVCDEFLVAASR
DPNPPPMPPTAVQRLKELGV

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320151, Length=265, Percent_Identity=27.9245283018868, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281364648, Length=213, Percent_Identity=25.8215962441315, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582856, Length=213, Percent_Identity=25.8215962441315, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582854, Length=213, Percent_Identity=25.8215962441315, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 29764; Mature: 29764

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLYLRSILFNAAFYICTLVQMILYTPFYFILPRKKAWIVPKLWARVNLWLQKHIAGTDC
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHCCCHHH
VVEGLENIPEGAYICAPKHQSAWDTYAFLPYLDDPVLILKRELMRIPLFGWYIAKMQMIP
HHHHHHHCCCCCEEECCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCHHHHHHHHEEEEE
VDRGSRVKALHSITKGAEKAIAEGRQILIYPEGTRRSPGAPPQYKYGIVHLYEALNLPVV
CCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEE
PIAHNAGLYWPRRKFLRYPGTIRSRILPPIPAGLPKEEFLRRLIESTETVCDEFLVAASR
EEECCCCCCCCHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
DPNPPPMPPTAVQRLKELGV
CCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLLYLRSILFNAAFYICTLVQMILYTPFYFILPRKKAWIVPKLWARVNLWLQKHIAGTDC
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHCCCHHH
VVEGLENIPEGAYICAPKHQSAWDTYAFLPYLDDPVLILKRELMRIPLFGWYIAKMQMIP
HHHHHHHCCCCCEEECCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCHHHHHHHHEEEEE
VDRGSRVKALHSITKGAEKAIAEGRQILIYPEGTRRSPGAPPQYKYGIVHLYEALNLPVV
CCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEE
PIAHNAGLYWPRRKFLRYPGTIRSRILPPIPAGLPKEEFLRRLIESTETVCDEFLVAASR
EEECCCCCCCCHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
DPNPPPMPPTAVQRLKELGV
CCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]