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The map label for this gene is ybbO [H]

Identifier: 23502825

GI number: 23502825

Start: 1904717

End: 1905559

Strand: Reverse

Name: ybbO [H]

Synonym: BR1977

Alternate gene names: 23502825

Gene position: 1905559-1904717 (Counterclockwise)

Preceding gene: 23502828

Following gene: 23502824

Centisome position: 90.41

GC content: 60.14

Gene sequence:

>843_bases
ATGGCATCAGCGGACGGAAAGCGAAGCATTCTCATTACCGGCTGTTCGTCCGGCATCGGCGCTTATTGCGCCGCGGCGCT
GCACAGCCGGGGCTGGCGCGTCTTTGCCACGGCGCGTCAAGAGAAGGACATAGCCGCCTTGCGAGCCGGGGGGCTTGAGG
CTTTCTATCTCGATTATGCCGAGCCGGAATCGATTGCCGCGCTGGTTGCGAATGTTCTGCAAGCCAGCGGAGGCAAGCTC
GATGCATTGTTCAACAATGGAGCCTATGCCCAGCCCGGTGCGGTGGAGGATTTGCCGGTCGAGGCGCTTCGCGCGCAATT
CGAGGCCAATTTCTTCGGCTGGCACGACCTGACGCGGCGTATCATCCCGGTCATGCGCACGCAAGGCCATGGGCGCATCG
TACATTGTTCCTCCATCCTTGGCCTTGTGCCTTTGAAATGGCGCGGCGCCTATGTGGCTTCAAAATTTGCCATTGAGGGG
CTGATGCTGGTGCAACGCATGGAACTGGAAGGGTCGGGCGTCGAAGTGTCGCTCATCGAGCCGGGGCCGATCGCCTCGCG
TTTTGCCCATAATGCAGCCATGCACGCCAGGGCGAATATCGATATGGAGGGCTCCGTTCATCGCGCGTTTTATCCGCAGC
AGATGGCGAAGCTTGAAAGTGGCGGCACGAAATCGAAGAACAAGCTTGGCCCGGAAGCGGTCTTTGATGTACTGCTTCAC
GCATTGGAGGCGCCGCGCCCACGCCCGCATTATGCGGTCACGAAGCCGGCGAAAATCGGTATTCTGGCACGACGCATACT
GCCTGCGCGCTGGCTTTACCGGATGCTGTCGGATCAGTCCTGA

Upstream 100 bases:

>100_bases
CTAAATCTAGCATCGGAGTAGAGATTGCAAGGGCGGCGGCGTTTTAAAGAGAGTGCGAATCAAGCACTGTGACGCAAACC
AAGCGGCAGGAAAACGGGAA

Downstream 100 bases:

>100_bases
TCGTCAGCGGGCAAGGGGAGGGAAACGGGATGGACGTTCTGTTCAAGGGCGCAGCCATGATCGCCATGCTGGCGGTGGCT
GTCGTGCTCATCATCGGGCT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MASADGKRSILITGCSSGIGAYCAAALHSRGWRVFATARQEKDIAALRAGGLEAFYLDYAEPESIAALVANVLQASGGKL
DALFNNGAYAQPGAVEDLPVEALRAQFEANFFGWHDLTRRIIPVMRTQGHGRIVHCSSILGLVPLKWRGAYVASKFAIEG
LMLVQRMELEGSGVEVSLIEPGPIASRFAHNAAMHARANIDMEGSVHRAFYPQQMAKLESGGTKSKNKLGPEAVFDVLLH
ALEAPRPRPHYAVTKPAKIGILARRILPARWLYRMLSDQS

Sequences:

>Translated_280_residues
MASADGKRSILITGCSSGIGAYCAAALHSRGWRVFATARQEKDIAALRAGGLEAFYLDYAEPESIAALVANVLQASGGKL
DALFNNGAYAQPGAVEDLPVEALRAQFEANFFGWHDLTRRIIPVMRTQGHGRIVHCSSILGLVPLKWRGAYVASKFAIEG
LMLVQRMELEGSGVEVSLIEPGPIASRFAHNAAMHARANIDMEGSVHRAFYPQQMAKLESGGTKSKNKLGPEAVFDVLLH
ALEAPRPRPHYAVTKPAKIGILARRILPARWLYRMLSDQS
>Mature_279_residues
ASADGKRSILITGCSSGIGAYCAAALHSRGWRVFATARQEKDIAALRAGGLEAFYLDYAEPESIAALVANVLQASGGKLD
ALFNNGAYAQPGAVEDLPVEALRAQFEANFFGWHDLTRRIIPVMRTQGHGRIVHCSSILGLVPLKWRGAYVASKFAIEGL
MLVQRMELEGSGVEVSLIEPGPIASRFAHNAAMHARANIDMEGSVHRAFYPQQMAKLESGGTKSKNKLGPEAVFDVLLHA
LEAPRPRPHYAVTKPAKIGILARRILPARWLYRMLSDQS

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI223718074, Length=260, Percent_Identity=33.8461538461538, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI7657478, Length=195, Percent_Identity=34.8717948717949, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI40548397, Length=274, Percent_Identity=29.9270072992701, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI214010158, Length=274, Percent_Identity=29.9270072992701, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI214010156, Length=274, Percent_Identity=29.9270072992701, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI22758144, Length=274, Percent_Identity=29.9270072992701, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI150247226, Length=278, Percent_Identity=30.9352517985612, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI19743808, Length=274, Percent_Identity=31.021897810219, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI44680136, Length=265, Percent_Identity=27.5471698113208, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI44680133, Length=265, Percent_Identity=27.5471698113208, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI17738292, Length=265, Percent_Identity=27.5471698113208, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=31.2820512820513, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI119392083, Length=261, Percent_Identity=31.4176245210728, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=31.9587628865979, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI22507405, Length=273, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI38348362, Length=185, Percent_Identity=31.3513513513514, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4504503, Length=277, Percent_Identity=27.4368231046931, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI157739938, Length=195, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI38424085, Length=184, Percent_Identity=31.5217391304348, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1786701, Length=270, Percent_Identity=36.6666666666667, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1787335, Length=194, Percent_Identity=27.319587628866, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=28.1767955801105, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=276, Percent_Identity=28.6231884057971, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71997402, Length=234, Percent_Identity=27.3504273504274, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17557780, Length=203, Percent_Identity=28.0788177339901, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17570069, Length=228, Percent_Identity=26.7543859649123, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193210355, Length=264, Percent_Identity=26.8939393939394, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=205, Percent_Identity=32.6829268292683, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=269, Percent_Identity=26.7657992565056, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=269, Percent_Identity=26.7657992565056, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=196, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=220, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=189, Percent_Identity=29.1005291005291, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=31.2820512820513, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24651139, Length=294, Percent_Identity=27.891156462585, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19922066, Length=193, Percent_Identity=30.0518134715026, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24580925, Length=202, Percent_Identity=31.6831683168317, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI23397609, Length=217, Percent_Identity=26.7281105990783, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28571526, Length=204, Percent_Identity=28.921568627451, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356301, Length=184, Percent_Identity=28.804347826087, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21357041, Length=207, Percent_Identity=27.536231884058, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30387; Mature: 30256

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASADGKRSILITGCSSGIGAYCAAALHSRGWRVFATARQEKDIAALRAGGLEAFYLDYA
CCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCEEEEECCC
EPESIAALVANVLQASGGKLDALFNNGAYAQPGAVEDLPVEALRAQFEANFFGWHDLTRR
CHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHH
IIPVMRTQGHGRIVHCSSILGLVPLKWRGAYVASKFAIEGLMLVQRMELEGSGVEVSLIE
HHHHHHCCCCCCEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
PGPIASRFAHNAAMHARANIDMEGSVHRAFYPQQMAKLESGGTKSKNKLGPEAVFDVLLH
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ALEAPRPRPHYAVTKPAKIGILARRILPARWLYRMLSDQS
HHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASADGKRSILITGCSSGIGAYCAAALHSRGWRVFATARQEKDIAALRAGGLEAFYLDYA
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCEEEEECCC
EPESIAALVANVLQASGGKLDALFNNGAYAQPGAVEDLPVEALRAQFEANFFGWHDLTRR
CHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHH
IIPVMRTQGHGRIVHCSSILGLVPLKWRGAYVASKFAIEGLMLVQRMELEGSGVEVSLIE
HHHHHHCCCCCCEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
PGPIASRFAHNAAMHARANIDMEGSVHRAFYPQQMAKLESGGTKSKNKLGPEAVFDVLLH
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ALEAPRPRPHYAVTKPAKIGILARRILPARWLYRMLSDQS
HHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]