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The map label for this gene is ftsK

Identifier: 23502746

GI number: 23502746

Start: 1828634

End: 1831198

Strand: Reverse

Name: ftsK

Synonym: BR1895

Alternate gene names: 23502746

Gene position: 1831198-1828634 (Counterclockwise)

Preceding gene: 23502747

Following gene: 23502745

Centisome position: 86.88

GC content: 61.29

Gene sequence:

>2565_bases
ATGCGGCAAGGATATTCGCCCTCATACCCGCTGCGTGACGAGCGGATTACGGAAGACAGGTTGCGGTTTGCCAATCTCGT
CCGCAGGCAGGTCTATATCCTTCTGGGGCTGGGGCTTCTTTCGCTCACCGCCATGGCGGTTGGCGCGCTTGCCACATGGA
ATGTCGCCGATCCAAGCTTCAGCCATGCCACCGACAATCCTGTCACCAATGCGCTCGGCTATCCGGGCGCCGTGTTCTCC
GATCTGGCCATGCAGTTCTTCGGCCTTGCCAGCGTTCCGGCGCTGCTGCCGCTTGCGGTCTGGTCGCTTCTCCTGATGAT
CCGGGGTTATATCGGGCGTATCGCCCGGCGCAGCCTTGCGTGGGTGGGGGCGGCGCTGCTCTTTGCCGCCATTGCAAGCT
GCTTAGCCGTGCCGCAAAGCTGGCCAATGCCAATCGGCCTTGGCGGTGTTTTCGGCGATATGCTGCTTCGGATACCGGGT
TTCTTCCTTGGCGGGTTCCCGCAAGGGGCTATTGCCTCCGCTATTGCGCTGGTTCTGGCTTTTCCAGCCTTGTGGTTCTG
TTTTTTTGCAAGCGGCATCATTGGTCGCGGGGCGGAAGCGGTCAATCCGGCCATGCTTTCGGCAAATCGTTCTGCCGATG
ATGAATTCGCGGATGAGGATGCAGACAATGAAGCCGGTGGCGGTTTCCACTTCATCGGTGCGCTGACCCATCTGGTGCTG
ATGACGACAGCCACGATCAGGCGCATGACCGGACTTGGCCGCCGCCGCTCGCGCGAGGATGATTTCGACGACATGCGCAT
GGTGCGCCGCAGTGCCGAAACCCGCAATGCGCCGCGCCGCGAACCCGGTTTCGGGGCGCCTGCCGCCGATGACGAACCGC
CTTTCGATATGGACGATATGGATGATGGCGCACCGCTTGCCGGTCAGGAATGGCATGATGCGCCGCCGCCCCGCGCCCGC
AAGGCGCGTGTGGAACAGGCCGCGCCGTCGCCGAAGCCCGGCCCGCGCGCCCAGCGCGAGGCGCAGCCTTCCTTCCTTAA
GGATAATGGTATCTTTGAAATGCCGTCGCTGCATTTCCTGGCCGAACCGAAGCTCGTGCAGCGCGACCCCGCGCTTTCCA
AGGATGCGCTGGAGCAGAATGCCCGTCTGCTTGAGGGCGTGCTGGAAGATTTCGGTGTGCGTGGCGAGATCATCAATGTC
AAACCCGGCCCCGTGGTCACGCTTTATGAGCTTGAACCGGCACCGGGCATCAAGTCCTCGCGCGTCATCGGCCTTGCCGA
CGATATTGCGCGCTCGATGAGCGCGATTGCCGCGCGTGTGGCTGTCATTCCGGGGCGCAACGCGATCGGTATCGAACTGC
CGAACCCCAAGCGCGAAATGGTCTATCTGCGTGAGATGCTGGCGAGCCGCGACTTTGAGCAATCGAAGGCGAAGCTTGCG
CTGGCACTCGGCAAGACCATCAATGGCGAGCCGGTCATTGCCGATATTGCCAAGATGCCGCACGTTCTGGTTGCGGGCAC
CACCGGCTCGGGCAAGTCGGTTGCGATCAACACCATGATCCTGTCGTTGCTCTATCGCATGACGCCGCAGGAATGCCGCC
TCATCATGATCGACCCCAAGATGCTGGAGCTTTCCGTCTATGACGGCATTCCGCATCTGCTGACGCCGGTTGTGACGGAC
CCGAAGAAGGCCGTTGTCGCGCTCAAATGGACCGTGCGCGAAATGGAAGACCGCTATCGCAAGATGTCGAAGGTCGGCGT
GCGCAATATAGACGGCTTCAACCAGCGTGTCGGTCTGGCGCAGAAAAAGGGCGAGCCGATTGCGCGCACGGTACAGACCG
GCTTCGACCGCAATACCGGCGAGGCGATCTACGAGACGGAAGAACTCGATCTCGAACCCATGCCCTATATCGTCGTGATT
ATCGACGAAATGGCCGACCTCATGATGGTCGCAGGCAAGGATATTGAAGGCGCGGTGCAGCGTCTGGCGCAGATGGCGCG
TGCGGCAGGCATTCACGTCATCATGGCGACGCAGCGCCCGTCGGTCGATGTCATCACCGGCACGATCAAGGCCAATTTCC
CGACCCGCATTTCCTTCCAGGTGACGTCGAAGATCGACAGCCGAACCATTCTGGGCGAACAGGGTGCCGAACAGCTTCTT
GGCCAGGGCGACATGCTGTTCATGGCGGGCGGCGGGCGCATCCAGCGCGTGCATGGGCCATTTGTCGGCGACGACGAGGT
GGAGCGCATCGTGCAGCATCTCAAGCTTCAGGGCGTGCCGGAATATCTCGATGCCATCACCGAGGATGAAGACGATGACG
AGGGCGGTAGCGGCCCGGCTGGAACCGGCAATCTGGAGGATTCCGACGATCCGTATGATCAGGCCGTGGCCGTCGTGCTG
CGCGACAAGAAGGCGTCCACATCCTATATTCAGCGCCGTCTCGGCATCGGCTATAATCGCGCTGCCTCAATCATCGAACG
CATGGAAGATGAGGGCATTGTCGGCCCGGCCAACCATGCGGGCAAGCGCGAAATACTGGTGCCCACGGGCGATGATGATT
TCTAA

Upstream 100 bases:

>100_bases
GAGGAATTAACTATCCGGCGATTAGGATCGGACCGATTCAGTGCGCCCCGAGCATGTCCGCTCACGGGCCAGCAAAAATA
TTCGGTTCGGGACAGGCTTT

Downstream 100 bases:

>100_bases
AGCTTTTCCAGCGGTTTAATCAAAACAGGAAATGCTCTGGAACTATATAATGCGGTGAATTTCAGGAGCTTGCGGCCTTC
ATGGCCTCACGCAGAACCGC

Product: cell division protein FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 854; Mature: 854

Protein sequence:

>854_residues
MRQGYSPSYPLRDERITEDRLRFANLVRRQVYILLGLGLLSLTAMAVGALATWNVADPSFSHATDNPVTNALGYPGAVFS
DLAMQFFGLASVPALLPLAVWSLLLMIRGYIGRIARRSLAWVGAALLFAAIASCLAVPQSWPMPIGLGGVFGDMLLRIPG
FFLGGFPQGAIASAIALVLAFPALWFCFFASGIIGRGAEAVNPAMLSANRSADDEFADEDADNEAGGGFHFIGALTHLVL
MTTATIRRMTGLGRRRSREDDFDDMRMVRRSAETRNAPRREPGFGAPAADDEPPFDMDDMDDGAPLAGQEWHDAPPPRAR
KARVEQAAPSPKPGPRAQREAQPSFLKDNGIFEMPSLHFLAEPKLVQRDPALSKDALEQNARLLEGVLEDFGVRGEIINV
KPGPVVTLYELEPAPGIKSSRVIGLADDIARSMSAIAARVAVIPGRNAIGIELPNPKREMVYLREMLASRDFEQSKAKLA
LALGKTINGEPVIADIAKMPHVLVAGTTGSGKSVAINTMILSLLYRMTPQECRLIMIDPKMLELSVYDGIPHLLTPVVTD
PKKAVVALKWTVREMEDRYRKMSKVGVRNIDGFNQRVGLAQKKGEPIARTVQTGFDRNTGEAIYETEELDLEPMPYIVVI
IDEMADLMMVAGKDIEGAVQRLAQMARAAGIHVIMATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEQGAEQLL
GQGDMLFMAGGGRIQRVHGPFVGDDEVERIVQHLKLQGVPEYLDAITEDEDDDEGGSGPAGTGNLEDSDDPYDQAVAVVL
RDKKASTSYIQRRLGIGYNRAASIIERMEDEGIVGPANHAGKREILVPTGDDDF

Sequences:

>Translated_854_residues
MRQGYSPSYPLRDERITEDRLRFANLVRRQVYILLGLGLLSLTAMAVGALATWNVADPSFSHATDNPVTNALGYPGAVFS
DLAMQFFGLASVPALLPLAVWSLLLMIRGYIGRIARRSLAWVGAALLFAAIASCLAVPQSWPMPIGLGGVFGDMLLRIPG
FFLGGFPQGAIASAIALVLAFPALWFCFFASGIIGRGAEAVNPAMLSANRSADDEFADEDADNEAGGGFHFIGALTHLVL
MTTATIRRMTGLGRRRSREDDFDDMRMVRRSAETRNAPRREPGFGAPAADDEPPFDMDDMDDGAPLAGQEWHDAPPPRAR
KARVEQAAPSPKPGPRAQREAQPSFLKDNGIFEMPSLHFLAEPKLVQRDPALSKDALEQNARLLEGVLEDFGVRGEIINV
KPGPVVTLYELEPAPGIKSSRVIGLADDIARSMSAIAARVAVIPGRNAIGIELPNPKREMVYLREMLASRDFEQSKAKLA
LALGKTINGEPVIADIAKMPHVLVAGTTGSGKSVAINTMILSLLYRMTPQECRLIMIDPKMLELSVYDGIPHLLTPVVTD
PKKAVVALKWTVREMEDRYRKMSKVGVRNIDGFNQRVGLAQKKGEPIARTVQTGFDRNTGEAIYETEELDLEPMPYIVVI
IDEMADLMMVAGKDIEGAVQRLAQMARAAGIHVIMATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEQGAEQLL
GQGDMLFMAGGGRIQRVHGPFVGDDEVERIVQHLKLQGVPEYLDAITEDEDDDEGGSGPAGTGNLEDSDDPYDQAVAVVL
RDKKASTSYIQRRLGIGYNRAASIIERMEDEGIVGPANHAGKREILVPTGDDDF
>Mature_854_residues
MRQGYSPSYPLRDERITEDRLRFANLVRRQVYILLGLGLLSLTAMAVGALATWNVADPSFSHATDNPVTNALGYPGAVFS
DLAMQFFGLASVPALLPLAVWSLLLMIRGYIGRIARRSLAWVGAALLFAAIASCLAVPQSWPMPIGLGGVFGDMLLRIPG
FFLGGFPQGAIASAIALVLAFPALWFCFFASGIIGRGAEAVNPAMLSANRSADDEFADEDADNEAGGGFHFIGALTHLVL
MTTATIRRMTGLGRRRSREDDFDDMRMVRRSAETRNAPRREPGFGAPAADDEPPFDMDDMDDGAPLAGQEWHDAPPPRAR
KARVEQAAPSPKPGPRAQREAQPSFLKDNGIFEMPSLHFLAEPKLVQRDPALSKDALEQNARLLEGVLEDFGVRGEIINV
KPGPVVTLYELEPAPGIKSSRVIGLADDIARSMSAIAARVAVIPGRNAIGIELPNPKREMVYLREMLASRDFEQSKAKLA
LALGKTINGEPVIADIAKMPHVLVAGTTGSGKSVAINTMILSLLYRMTPQECRLIMIDPKMLELSVYDGIPHLLTPVVTD
PKKAVVALKWTVREMEDRYRKMSKVGVRNIDGFNQRVGLAQKKGEPIARTVQTGFDRNTGEAIYETEELDLEPMPYIVVI
IDEMADLMMVAGKDIEGAVQRLAQMARAAGIHVIMATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEQGAEQLL
GQGDMLFMAGGGRIQRVHGPFVGDDEVERIVQHLKLQGVPEYLDAITEDEDDDEGGSGPAGTGNLEDSDDPYDQAVAVVL
RDKKASTSYIQRRLGIGYNRAASIIERMEDEGIVGPANHAGKREILVPTGDDDF

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=497, Percent_Identity=53.7223340040241, Blast_Score=499, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK_BRUSU (Q8FYI0)

Other databases:

- EMBL:   AE014291
- RefSeq:   NP_698873.1
- ProteinModelPortal:   Q8FYI0
- GeneID:   1167595
- GenomeReviews:   AE014291_GR
- KEGG:   bms:BR1895
- NMPDR:   fig|204722.1.peg.1830
- TIGR:   BR1895
- HOGENOM:   HBG662140
- OMA:   IGVRNID
- ProtClustDB:   CLSK898034
- BioCyc:   BSUI204722:BR_1895-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 92781; Mature: 92781

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe62ea48)-; HASH(0xf6bfcd8)-; HASH(0xf80c668)-; HASH(0xf552e8c)-; HASH(0xf02fc18)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQGYSPSYPLRDERITEDRLRFANLVRRQVYILLGLGLLSLTAMAVGALATWNVADPSF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SHATDNPVTNALGYPGAVFSDLAMQFFGLASVPALLPLAVWSLLLMIRGYIGRIARRSLA
CCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVGAALLFAAIASCLAVPQSWPMPIGLGGVFGDMLLRIPGFFLGGFPQGAIASAIALVLA
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHH
FPALWFCFFASGIIGRGAEAVNPAMLSANRSADDEFADEDADNEAGGGFHFIGALTHLVL
HHHHHHHHHHHHHHCCCCHHCCHHHHCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHH
MTTATIRRMTGLGRRRSREDDFDDMRMVRRSAETRNAPRREPGFGAPAADDEPPFDMDDM
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
DDGAPLAGQEWHDAPPPRARKARVEQAAPSPKPGPRAQREAQPSFLKDNGIFEMPSLHFL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCEECCCCHHH
AEPKLVQRDPALSKDALEQNARLLEGVLEDFGVRGEIINVKPGPVVTLYELEPAPGIKSS
CCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCCC
RVIGLADDIARSMSAIAARVAVIPGRNAIGIELPNPKREMVYLREMLASRDFEQSKAKLA
CEEECHHHHHHHHHHHHHHHEEECCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHH
LALGKTINGEPVIADIAKMPHVLVAGTTGSGKSVAINTMILSLLYRMTPQECRLIMIDPK
HHHCCCCCCCCHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCC
MLELSVYDGIPHLLTPVVTDPKKAVVALKWTVREMEDRYRKMSKVGVRNIDGFNQRVGLA
EEEEEHHCCCHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCH
QKKGEPIARTVQTGFDRNTGEAIYETEELDLEPMPYIVVIIDEMADLMMVAGKDIEGAVQ
HHCCCHHHHHHHHCCCCCCCCCEEEHHHCCCCCCCEEEEEHHHHHHHHHHCCCCHHHHHH
RLAQMARAAGIHVIMATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEQGAEQLL
HHHHHHHHCCEEEEEECCCCCCEEEEEEEEECCCCEEEEEEECCCCCHHHHCHHHHHHHH
GQGDMLFMAGGGRIQRVHGPFVGDDEVERIVQHLKLQGVPEYLDAITEDEDDDEGGSGPA
CCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCC
GTGNLEDSDDPYDQAVAVVLRDKKASTSYIQRRLGIGYNRAASIIERMEDEGIVGPANHA
CCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
GKREILVPTGDDDF
CCEEEEECCCCCCH
>Mature Secondary Structure
MRQGYSPSYPLRDERITEDRLRFANLVRRQVYILLGLGLLSLTAMAVGALATWNVADPSF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SHATDNPVTNALGYPGAVFSDLAMQFFGLASVPALLPLAVWSLLLMIRGYIGRIARRSLA
CCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVGAALLFAAIASCLAVPQSWPMPIGLGGVFGDMLLRIPGFFLGGFPQGAIASAIALVLA
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHH
FPALWFCFFASGIIGRGAEAVNPAMLSANRSADDEFADEDADNEAGGGFHFIGALTHLVL
HHHHHHHHHHHHHHCCCCHHCCHHHHCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHH
MTTATIRRMTGLGRRRSREDDFDDMRMVRRSAETRNAPRREPGFGAPAADDEPPFDMDDM
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
DDGAPLAGQEWHDAPPPRARKARVEQAAPSPKPGPRAQREAQPSFLKDNGIFEMPSLHFL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCEECCCCHHH
AEPKLVQRDPALSKDALEQNARLLEGVLEDFGVRGEIINVKPGPVVTLYELEPAPGIKSS
CCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCCC
RVIGLADDIARSMSAIAARVAVIPGRNAIGIELPNPKREMVYLREMLASRDFEQSKAKLA
CEEECHHHHHHHHHHHHHHHEEECCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHH
LALGKTINGEPVIADIAKMPHVLVAGTTGSGKSVAINTMILSLLYRMTPQECRLIMIDPK
HHHCCCCCCCCHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCC
MLELSVYDGIPHLLTPVVTDPKKAVVALKWTVREMEDRYRKMSKVGVRNIDGFNQRVGLA
EEEEEHHCCCHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCH
QKKGEPIARTVQTGFDRNTGEAIYETEELDLEPMPYIVVIIDEMADLMMVAGKDIEGAVQ
HHCCCHHHHHHHHCCCCCCCCCEEEHHHCCCCCCCEEEEEHHHHHHHHHHCCCCHHHHHH
RLAQMARAAGIHVIMATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEQGAEQLL
HHHHHHHHCCEEEEEECCCCCCEEEEEEEEECCCCEEEEEEECCCCCHHHHCHHHHHHHH
GQGDMLFMAGGGRIQRVHGPFVGDDEVERIVQHLKLQGVPEYLDAITEDEDDDEGGSGPA
CCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCC
GTGNLEDSDDPYDQAVAVVLRDKKASTSYIQRRLGIGYNRAASIIERMEDEGIVGPANHA
CCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
GKREILVPTGDDDF
CCEEEEECCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12271122