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The map label for this gene is ftsZ [H]

Identifier: 23502296

GI number: 23502296

Start: 1380439

End: 1382139

Strand: Reverse

Name: ftsZ [H]

Synonym: BR1425

Alternate gene names: 23502296

Gene position: 1382139-1380439 (Counterclockwise)

Preceding gene: 23502297

Following gene: 23502295

Centisome position: 65.57

GC content: 63.9

Gene sequence:

>1701_bases
ATGACTATCAATCTGCAAAAGCCGGATATCACCGAGCTGAAGCCCCGCATCACCGTATTCGGTGTCGGCGGCGGCGGCGG
CAATGCGGTCAACAACATGATCAATGCCGGCCTGCGCGGCGTGGATTTCGTTGTGGCCAACACCGACGCGCAGGCTTTGA
CCATGTCGAAGTCCGACCGCATCATCCAGCTTGGCGCTGCCGTGACGGAAGGCCTCGGCGCCGGTTCGCAGCCGGAAGTT
GGTCGTGCTGCCGCGGAAGAATGCATCGACGAAATCGTCGATCACCTGAACGGTACGCATATGTGCTTTGTGACCGCAGG
CATGGGCGGCGGCACCGGCACGGGCGCTGCGCCTGTCGTGGCACGCGCTGCCCGCGAACGCGGCATCCTCACCGTCGGCG
TTGTGACCAAGCCTTTCCACTTTGAAGGCGCCCGCCGCATGAAAACTGCCGATCTGGGCATTGAAGAACTGCAGAAGAAT
GTCGATACGCTCATCGTCATTCCGAACCAGAACCTGTTCCGCATCGCCAACGACAAGACCACTTTTGCCGACGCTTTTGC
GATGGCTGATCAGGTGCTCTATTCGGGTGTTGCCTGCATCACCGACCTGATGGTCAAGGAAGGCCTGATTAACCTCGACT
TCGCTGACGTCCGCTCGGTCATGCGCGAAATGGGCAAGGCCATGATGGGCACGGGCGAAGCTTCCGGTGAAGGCCGTGCG
ATGGCTGCTGCCGAGGCCGCAATCGCCAATCCGCTGCTCGACGAAACCTCCATGCGCGGTGCGAAGGGCCTTCTGATCTC
GATCACCGGTGGCCGCGACATGACCCTGTTCGAGGTCGATGAAGCTGCGACCCGTATTCGTGAAGAAGTTGACCCGGAAG
CCAACATCATCCTTGGCGCAACCTTCGACGAAGGCCTCGAAGGCGTCATCCGTGTTTCCGTGGTTGCGACCGGCATCGAC
AAGCAGCAAGGAGATGCGGCGCCTGCGCCGCTGGAATTTCGCCAGCCAGTGAAGCCGACTGCCGCCCAGGCCAAGCCGAT
GGCTCCGCATGGCGCGCTGCGTCCGCCTGTTGCCGAACAGCCGCGTCAGGCCGATCCGGTCGCCCAGGTCATCCAGGCCG
CCGAAGCCGAAATGCCGGTTTCTCCGGCTGCGCCTGCCGCATCGGCTGAGCCGGAATTCCGTCCGCAGAGCCGCATTTTC
CAGGCTCCCGCGCCGGAAGCTTTTGAACGCGCCCCGGTTGCCCGCGCGCCGATGCAGCCGGCTCAGGCAATGCATGCCCC
CCAGCCGCAGCAGTATCAGCAGCCGCAGATGCACGAACAGCCGGTTCGTGAGCCGCGCCCTGCACCGCGTATGCCTGCCG
TTTCCGACTTCCCGCCGGTGGCACAGGCAGAAATCAACGCCCGCCGTGCCCCGCAGCAGCCTGTACAGGAAGAGCCGCGC
GGCCCGATGGGCCTTCTCAAGCGCCTGACCCATGGTCTGTCGCGCCGTGAGGAAGAACAGCCGGCTGCCCGTCTGGAGCC
TGCACAGCACCGCGAGCCGGGTATGCGCCCAGCCGAACCGCGCCGCCCGATGCAGCAGGATTCGTCGATCTATGCACCGC
GCCGCGGTCAGCTTGACGATCAGGGCCGTCCGCAGCCGCGGACAGCTTCTGAAGAAGATCAGCTCGAAATCCCGGCTTTC
CTGCGCCGCCAGTCGAACTGA

Upstream 100 bases:

>100_bases
TTGAGTAACATTGCGTGATTTGGGGCGTAACCATCAGCGTAATAACCAATCGGCACCGCGGCGGCGAAGCGGTGGACAGG
CTTAAGAGGAACAAGGACCA

Downstream 100 bases:

>100_bases
TCTTTACCCTGTAAAAGCCTTTCAAAGCCCGCCTGTTTTCAGGCGGGCTTCTTTTATTTCAAGCTTCACTACAGTTGCAT
TCTTCGTGATGCCGGGGCTG

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MTINLQKPDITELKPRITVFGVGGGGGNAVNNMINAGLRGVDFVVANTDAQALTMSKSDRIIQLGAAVTEGLGAGSQPEV
GRAAAEECIDEIVDHLNGTHMCFVTAGMGGGTGTGAAPVVARAARERGILTVGVVTKPFHFEGARRMKTADLGIEELQKN
VDTLIVIPNQNLFRIANDKTTFADAFAMADQVLYSGVACITDLMVKEGLINLDFADVRSVMREMGKAMMGTGEASGEGRA
MAAAEAAIANPLLDETSMRGAKGLLISITGGRDMTLFEVDEAATRIREEVDPEANIILGATFDEGLEGVIRVSVVATGID
KQQGDAAPAPLEFRQPVKPTAAQAKPMAPHGALRPPVAEQPRQADPVAQVIQAAEAEMPVSPAAPAASAEPEFRPQSRIF
QAPAPEAFERAPVARAPMQPAQAMHAPQPQQYQQPQMHEQPVREPRPAPRMPAVSDFPPVAQAEINARRAPQQPVQEEPR
GPMGLLKRLTHGLSRREEEQPAARLEPAQHREPGMRPAEPRRPMQQDSSIYAPRRGQLDDQGRPQPRTASEEDQLEIPAF
LRRQSN

Sequences:

>Translated_566_residues
MTINLQKPDITELKPRITVFGVGGGGGNAVNNMINAGLRGVDFVVANTDAQALTMSKSDRIIQLGAAVTEGLGAGSQPEV
GRAAAEECIDEIVDHLNGTHMCFVTAGMGGGTGTGAAPVVARAARERGILTVGVVTKPFHFEGARRMKTADLGIEELQKN
VDTLIVIPNQNLFRIANDKTTFADAFAMADQVLYSGVACITDLMVKEGLINLDFADVRSVMREMGKAMMGTGEASGEGRA
MAAAEAAIANPLLDETSMRGAKGLLISITGGRDMTLFEVDEAATRIREEVDPEANIILGATFDEGLEGVIRVSVVATGID
KQQGDAAPAPLEFRQPVKPTAAQAKPMAPHGALRPPVAEQPRQADPVAQVIQAAEAEMPVSPAAPAASAEPEFRPQSRIF
QAPAPEAFERAPVARAPMQPAQAMHAPQPQQYQQPQMHEQPVREPRPAPRMPAVSDFPPVAQAEINARRAPQQPVQEEPR
GPMGLLKRLTHGLSRREEEQPAARLEPAQHREPGMRPAEPRRPMQQDSSIYAPRRGQLDDQGRPQPRTASEEDQLEIPAF
LRRQSN
>Mature_565_residues
TINLQKPDITELKPRITVFGVGGGGGNAVNNMINAGLRGVDFVVANTDAQALTMSKSDRIIQLGAAVTEGLGAGSQPEVG
RAAAEECIDEIVDHLNGTHMCFVTAGMGGGTGTGAAPVVARAARERGILTVGVVTKPFHFEGARRMKTADLGIEELQKNV
DTLIVIPNQNLFRIANDKTTFADAFAMADQVLYSGVACITDLMVKEGLINLDFADVRSVMREMGKAMMGTGEASGEGRAM
AAAEAAIANPLLDETSMRGAKGLLISITGGRDMTLFEVDEAATRIREEVDPEANIILGATFDEGLEGVIRVSVVATGIDK
QQGDAAPAPLEFRQPVKPTAAQAKPMAPHGALRPPVAEQPRQADPVAQVIQAAEAEMPVSPAAPAASAEPEFRPQSRIFQ
APAPEAFERAPVARAPMQPAQAMHAPQPQQYQQPQMHEQPVREPRPAPRMPAVSDFPPVAQAEINARRAPQQPVQEEPRG
PMGLLKRLTHGLSRREEEQPAARLEPAQHREPGMRPAEPRRPMQQDSSIYAPRRGQLDDQGRPQPRTASEEDQLEIPAFL
RRQSN

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=368, Percent_Identity=45.6521739130435, Blast_Score=259, Evalue=3e-70,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017844
- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 60656; Mature: 60525

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINLQKPDITELKPRITVFGVGGGGGNAVNNMINAGLRGVDFVVANTDAQALTMSKSDR
CEECCCCCCHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCC
IIQLGAAVTEGLGAGSQPEVGRAAAEECIDEIVDHLNGTHMCFVTAGMGGGTGTGAAPVV
EEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHH
ARAARERGILTVGVVTKPFHFEGARRMKTADLGIEELQKNVDTLIVIPNQNLFRIANDKT
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCCHHHHHCCCCEEEEECCCCEEEEECCCC
TFADAFAMADQVLYSGVACITDLMVKEGLINLDFADVRSVMREMGKAMMGTGEASGEGRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCH
MAAAEAAIANPLLDETSMRGAKGLLISITGGRDMTLFEVDEAATRIREEVDPEANIILGA
HHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCEEEEC
TFDEGLEGVIRVSVVATGIDKQQGDAAPAPLEFRQPVKPTAAQAKPMAPHGALRPPVAEQ
CHHHHCHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCC
PRQADPVAQVIQAAEAEMPVSPAAPAASAEPEFRPQSRIFQAPAPEAFERAPVARAPMQP
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEECCCCCHHHHHCCCCCCCCCH
AQAMHAPQPQQYQQPQMHEQPVREPRPAPRMPAVSDFPPVAQAEINARRAPQQPVQEEPR
HHHHCCCCCHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHCCC
GPMGLLKRLTHGLSRREEEQPAARLEPAQHREPGMRPAEPRRPMQQDSSIYAPRRGQLDD
CHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QGRPQPRTASEEDQLEIPAFLRRQSN
CCCCCCCCCCCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
TINLQKPDITELKPRITVFGVGGGGGNAVNNMINAGLRGVDFVVANTDAQALTMSKSDR
EECCCCCCHHHCCCCEEEEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCC
IIQLGAAVTEGLGAGSQPEVGRAAAEECIDEIVDHLNGTHMCFVTAGMGGGTGTGAAPVV
EEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHH
ARAARERGILTVGVVTKPFHFEGARRMKTADLGIEELQKNVDTLIVIPNQNLFRIANDKT
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHCCHHHHHCCCCEEEEECCCCEEEEECCCC
TFADAFAMADQVLYSGVACITDLMVKEGLINLDFADVRSVMREMGKAMMGTGEASGEGRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCH
MAAAEAAIANPLLDETSMRGAKGLLISITGGRDMTLFEVDEAATRIREEVDPEANIILGA
HHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCEEEEC
TFDEGLEGVIRVSVVATGIDKQQGDAAPAPLEFRQPVKPTAAQAKPMAPHGALRPPVAEQ
CHHHHCHHHEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCC
PRQADPVAQVIQAAEAEMPVSPAAPAASAEPEFRPQSRIFQAPAPEAFERAPVARAPMQP
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEECCCCCHHHHHCCCCCCCCCH
AQAMHAPQPQQYQQPQMHEQPVREPRPAPRMPAVSDFPPVAQAEINARRAPQQPVQEEPR
HHHHCCCCCHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHCCC
GPMGLLKRLTHGLSRREEEQPAARLEPAQHREPGMRPAEPRRPMQQDSSIYAPRRGQLDD
CHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QGRPQPRTASEEDQLEIPAFLRRQSN
CCCCCCCCCCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1653222; 9352931; 11481430 [H]