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The map label for this gene is hflK [H]

Identifier: 23502268

GI number: 23502268

Start: 1351199

End: 1352347

Strand: Reverse

Name: hflK [H]

Synonym: BR1397

Alternate gene names: 23502268

Gene position: 1352347-1351199 (Counterclockwise)

Preceding gene: 23502269

Following gene: 23502267

Centisome position: 64.16

GC content: 58.92

Gene sequence:

>1149_bases
ATGCCCTGGAGCAATCAGAATGGCGGCGGCGGCCCGTGGGGCGGCGATAACAACAACAATAATAATAATGGACCTTGGGG
GCAGGGGCCAAAGGGGCCGCGTGGCGGCGGCCAGAACACGCCGCCCGACCTTGAAGATATTCTGCGCAAAGGGCAGGATC
GGTTGAAGCAGGTTTTCCCCGGTGGCGGCGGCCGAAAGGGCAGCAACCGCCCGATCTATTTCCTCATTGGCGCGGCAGTA
TTGGGTTTCTGGCTGTTCCAGTCGGTCTATACAGTCCAGCCGGACGAACTCGCCGTGGAGCTGCGCTTCGGCAAGCCGAA
GGAAGAGGTTTCCGAACCGGGCCCGCACTTCCATTGGTGGCCGTTCGAGACCTATGAAAAGGCGCAGATCGTCGAAAAGC
AGATCAATATCGGCGGGCAGGGTACGCGCAATGCGACGCAGGGCCTGATGCTGACGGGTGATCAGAACATCGTCAACGTG
CAGTTCTCGGTGCTTTACCGTGTTTCCGATCCGCGCGCCTATCTCTTCAATGTGGATAGCCCTGACGCGATGGTGCAGCA
GGTTTCCGAAAGCGCGATCCGCGAGATCGTCGGTCGCCGTCCGGCACAGGATGTTTTCCGCGACAATCGCTCGGCCATTG
CCCAGAGCGTGCGCGATATCGTTCAGCAGACGCTCGACAATTACAAGGCCGGCATCCAGATCAATGCCGTTTCGATTGAA
GATGCGCCCCCCCCGCGTGAAGTGGCCGATGCATTTGACGAAGTTCAGCGTGCCGAACAGGACGAGGACCGCTTCGTGGA
AGAATCGAACCAGTATTCCAACCAGAAGCTGGGTCAGGCGCGCGGTGAAGCGGCGCAGCTTCGTGAAGAAGCCGCCGCTT
ACAAGAACCGTGTCGTTCAGGACGCTGAAGGTGAAGCCCAGCGCTTCAGTTCGGTGCTGAAAGAGTATCAGAAGGCCCCG
GAAGTCACCCGTAACCGTCTCTTCCTTGAAACCATGGAAGAGGTGCTGAAGGGCACCAAGAAGGTCATTGTCGAACCCGG
CAAGGATGTAGTGCCTTATCTGCCGCTGCATGAATTGATGCAGAAGCAGCCGAGCACCGGCGTAAAGGCCCCCACCACGA
CGACCACCACTGGCGGAGGTAATCAGTAA

Upstream 100 bases:

>100_bases
CTTTGCGTTGAAAGCGGCCCTCGCGATGCCTATAAAACGGAAACATTAGTTGATGACGGAAGGCCAAGCTTGCTTTTCGT
CACCCGGACGAGAGGTGAGG

Downstream 100 bases:

>100_bases
TGACCCAGAACAGGCTCCCGATCATTGTCGGCTTCATTGCCGTCATCGCTTTCCTGCTCTATTCCTCCGTGTTCATCGTG
ACCGAACGCCAGCAGGCTAT

Product: hflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MPWSNQNGGGGPWGGDNNNNNNNGPWGQGPKGPRGGGQNTPPDLEDILRKGQDRLKQVFPGGGGRKGSNRPIYFLIGAAV
LGFWLFQSVYTVQPDELAVELRFGKPKEEVSEPGPHFHWWPFETYEKAQIVEKQINIGGQGTRNATQGLMLTGDQNIVNV
QFSVLYRVSDPRAYLFNVDSPDAMVQQVSESAIREIVGRRPAQDVFRDNRSAIAQSVRDIVQQTLDNYKAGIQINAVSIE
DAPPPREVADAFDEVQRAEQDEDRFVEESNQYSNQKLGQARGEAAQLREEAAAYKNRVVQDAEGEAQRFSSVLKEYQKAP
EVTRNRLFLETMEEVLKGTKKVIVEPGKDVVPYLPLHELMQKQPSTGVKAPTTTTTTGGGNQ

Sequences:

>Translated_382_residues
MPWSNQNGGGGPWGGDNNNNNNNGPWGQGPKGPRGGGQNTPPDLEDILRKGQDRLKQVFPGGGGRKGSNRPIYFLIGAAV
LGFWLFQSVYTVQPDELAVELRFGKPKEEVSEPGPHFHWWPFETYEKAQIVEKQINIGGQGTRNATQGLMLTGDQNIVNV
QFSVLYRVSDPRAYLFNVDSPDAMVQQVSESAIREIVGRRPAQDVFRDNRSAIAQSVRDIVQQTLDNYKAGIQINAVSIE
DAPPPREVADAFDEVQRAEQDEDRFVEESNQYSNQKLGQARGEAAQLREEAAAYKNRVVQDAEGEAQRFSSVLKEYQKAP
EVTRNRLFLETMEEVLKGTKKVIVEPGKDVVPYLPLHELMQKQPSTGVKAPTTTTTTGGGNQ
>Mature_381_residues
PWSNQNGGGGPWGGDNNNNNNNGPWGQGPKGPRGGGQNTPPDLEDILRKGQDRLKQVFPGGGGRKGSNRPIYFLIGAAVL
GFWLFQSVYTVQPDELAVELRFGKPKEEVSEPGPHFHWWPFETYEKAQIVEKQINIGGQGTRNATQGLMLTGDQNIVNVQ
FSVLYRVSDPRAYLFNVDSPDAMVQQVSESAIREIVGRRPAQDVFRDNRSAIAQSVRDIVQQTLDNYKAGIQINAVSIED
APPPREVADAFDEVQRAEQDEDRFVEESNQYSNQKLGQARGEAAQLREEAAAYKNRVVQDAEGEAQRFSSVLKEYQKAPE
VTRNRLFLETMEEVLKGTKKVIVEPGKDVVPYLPLHELMQKQPSTGVKAPTTTTTTGGGNQ

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=403, Percent_Identity=33.7468982630273, Blast_Score=189, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 42321; Mature: 42189

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWSNQNGGGGPWGGDNNNNNNNGPWGQGPKGPRGGGQNTPPDLEDILRKGQDRLKQVFP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
GGGGRKGSNRPIYFLIGAAVLGFWLFQSVYTVQPDELAVELRFGKPKEEVSEPGPHFHWW
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCHHEEEEEECCCCHHHHCCCCCCEECC
PFETYEKAQIVEKQINIGGQGTRNATQGLMLTGDQNIVNVQFSVLYRVSDPRAYLFNVDS
CCCHHHHHHHHHHHHCCCCCCCCHHHCCEEEECCCCEEEEEEEEEEEECCCCEEEEECCC
PDAMVQQVSESAIREIVGRRPAQDVFRDNRSAIAQSVRDIVQQTLDNYKAGIQINAVSIE
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEC
DAPPPREVADAFDEVQRAEQDEDRFVEESNQYSNQKLGQARGEAAQLREEAAAYKNRVVQ
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
DAEGEAQRFSSVLKEYQKAPEVTRNRLFLETMEEVLKGTKKVIVEPGKDVVPYLPLHELM
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCCCCHHHHH
QKQPSTGVKAPTTTTTTGGGNQ
HCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PWSNQNGGGGPWGGDNNNNNNNGPWGQGPKGPRGGGQNTPPDLEDILRKGQDRLKQVFP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
GGGGRKGSNRPIYFLIGAAVLGFWLFQSVYTVQPDELAVELRFGKPKEEVSEPGPHFHWW
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCHHEEEEEECCCCHHHHCCCCCCEECC
PFETYEKAQIVEKQINIGGQGTRNATQGLMLTGDQNIVNVQFSVLYRVSDPRAYLFNVDS
CCCHHHHHHHHHHHHCCCCCCCCHHHCCEEEECCCCEEEEEEEEEEEECCCCEEEEECCC
PDAMVQQVSESAIREIVGRRPAQDVFRDNRSAIAQSVRDIVQQTLDNYKAGIQINAVSIE
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEC
DAPPPREVADAFDEVQRAEQDEDRFVEESNQYSNQKLGQARGEAAQLREEAAAYKNRVVQ
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
DAEGEAQRFSSVLKEYQKAPEVTRNRLFLETMEEVLKGTKKVIVEPGKDVVPYLPLHELM
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCCCCHHHHH
QKQPSTGVKAPTTTTTTGGGNQ
HCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]