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The map label for this gene is hflC [H]

Identifier: 23502267

GI number: 23502267

Start: 1350297

End: 1351199

Strand: Reverse

Name: hflC [H]

Synonym: BR1396

Alternate gene names: 23502267

Gene position: 1351199-1350297 (Counterclockwise)

Preceding gene: 23502268

Following gene: 23502266

Centisome position: 64.1

GC content: 60.13

Gene sequence:

>903_bases
ATGACCCAGAACAGGCTCCCGATCATTGTCGGCTTCATTGCCGTCATCGCTTTCCTGCTCTATTCCTCCGTGTTCATCGT
GACCGAACGCCAGCAGGCTATCGTTCTGCGTTTCGGCCAGATCGTGGATGTGAAGACGAAGCCGGGCATCTATTTCAAGC
TGCCTTTCAGCTTTATGGATGCCGATACGGTGCAGATGGTCGATGACCGCCTGCTGCGTTTCGACCTCGACGATATCCGT
GTGCAGGTTTCCGGCGGCAAGTTCTACGATGTGGATGCTTTCCTCGTCTATCGCATCACGGATGCCCGCAAGTTCCGCGA
AACGGTTTCCGGCAGCACGCTTCTCGCCGAACAGCGCCTGCGTACCCGTCTCGATGCGGCTCTGCGCAGTGTTTACGGCC
AGCGTGGCTTCGAGGCCGCTTTGTCGGAAGAGCGCGGCGATATGATGCGTGAAGTGCGCGACCAGCTTCGCCCCGATGCG
ACATCGCTTGGCCTGACCATCGCCGATGTTCGTATCCGCCGGACCGATCTTACGACGGAAGTATCGCAGCAGACCTATGA
CCGTATGAAGGCGGAACGCCTGGCGGAAGCGGAACGCCTGCGGGCGCGTGGCCGCGAAGCGGCGCAGCGGATCCGCGCTG
TCGCGGATCGTCAGGTTGTGGAAACGCTTGCCGAAGCGCGCAAGGAATCGGAAATCCTTCGCGGTGAGGGCGATGCCCAG
CGCAGCGAGATCTTCGCCAAATCCGCATCGGAAGATCCGGGCTTCTTCGCCTTCTACCGTTCGATGGCGGCTTATCGTCG
GGCGCTGGAAACGCCGGATACCACGCTTGTCCTCTCGCCGGATTCGGAGTTCTTCAAGTTCTTCCGTGATGCCGGTGGCA
AGCTGGCAACGCCGAGCCAATAA

Upstream 100 bases:

>100_bases
TAGTGCCTTATCTGCCGCTGCATGAATTGATGCAGAAGCAGCCGAGCACCGGCGTAAAGGCCCCCACCACGACGACCACC
ACTGGCGGAGGTAATCAGTA

Downstream 100 bases:

>100_bases
CAAGCAGGAACAGGCGCTCATGAGCGATTTTCTAGCCGCCGTAGGTCTTCTCTTCGTTCTCGAAGGGCTGCTCTACGGCG
GCTTTCCTTCTTTGGCCAAG

Product: hflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTQNRLPIIVGFIAVIAFLLYSSVFIVTERQQAIVLRFGQIVDVKTKPGIYFKLPFSFMDADTVQMVDDRLLRFDLDDIR
VQVSGGKFYDVDAFLVYRITDARKFRETVSGSTLLAEQRLRTRLDAALRSVYGQRGFEAALSEERGDMMREVRDQLRPDA
TSLGLTIADVRIRRTDLTTEVSQQTYDRMKAERLAEAERLRARGREAAQRIRAVADRQVVETLAEARKESEILRGEGDAQ
RSEIFAKSASEDPGFFAFYRSMAAYRRALETPDTTLVLSPDSEFFKFFRDAGGKLATPSQ

Sequences:

>Translated_300_residues
MTQNRLPIIVGFIAVIAFLLYSSVFIVTERQQAIVLRFGQIVDVKTKPGIYFKLPFSFMDADTVQMVDDRLLRFDLDDIR
VQVSGGKFYDVDAFLVYRITDARKFRETVSGSTLLAEQRLRTRLDAALRSVYGQRGFEAALSEERGDMMREVRDQLRPDA
TSLGLTIADVRIRRTDLTTEVSQQTYDRMKAERLAEAERLRARGREAAQRIRAVADRQVVETLAEARKESEILRGEGDAQ
RSEIFAKSASEDPGFFAFYRSMAAYRRALETPDTTLVLSPDSEFFKFFRDAGGKLATPSQ
>Mature_299_residues
TQNRLPIIVGFIAVIAFLLYSSVFIVTERQQAIVLRFGQIVDVKTKPGIYFKLPFSFMDADTVQMVDDRLLRFDLDDIRV
QVSGGKFYDVDAFLVYRITDARKFRETVSGSTLLAEQRLRTRLDAALRSVYGQRGFEAALSEERGDMMREVRDQLRPDAT
SLGLTIADVRIRRTDLTTEVSQQTYDRMKAERLAEAERLRARGREAAQRIRAVADRQVVETLAEARKESEILRGEGDAQR
SEIFAKSASEDPGFFAFYRSMAAYRRALETPDTTLVLSPDSEFFKFFRDAGGKLATPSQ

Specific function: HflC and HflK govern the stability of phage lambda cII protein and have been proposed to encode or regulate a cII- specific protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=315, Percent_Identity=34.9206349206349, Blast_Score=173, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 34142; Mature: 34011

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQNRLPIIVGFIAVIAFLLYSSVFIVTERQQAIVLRFGQIVDVKTKPGIYFKLPFSFMD
CCCCCCHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHCCEEEEECCCCEEEEECHHHCC
ADTVQMVDDRLLRFDLDDIRVQVSGGKFYDVDAFLVYRITDARKFRETVSGSTLLAEQRL
CHHHHHHHHHHHHCCHHHEEEEECCCEEEEECEEEEEEEHHHHHHHHHHCCCHHHHHHHH
RTRLDAALRSVYGQRGFEAALSEERGDMMREVRDQLRPDATSLGLTIADVRIRRTDLTTE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCEEEEHEEEEHHHHHHH
VSQQTYDRMKAERLAEAERLRARGREAAQRIRAVADRQVVETLAEARKESEILRGEGDAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
RSEIFAKSASEDPGFFAFYRSMAAYRRALETPDTTLVLSPDSEFFKFFRDAGGKLATPSQ
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TQNRLPIIVGFIAVIAFLLYSSVFIVTERQQAIVLRFGQIVDVKTKPGIYFKLPFSFMD
CCCCCHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHCCEEEEECCCCEEEEECHHHCC
ADTVQMVDDRLLRFDLDDIRVQVSGGKFYDVDAFLVYRITDARKFRETVSGSTLLAEQRL
CHHHHHHHHHHHHCCHHHEEEEECCCEEEEECEEEEEEEHHHHHHHHHHCCCHHHHHHHH
RTRLDAALRSVYGQRGFEAALSEERGDMMREVRDQLRPDATSLGLTIADVRIRRTDLTTE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCEEEEHEEEEHHHHHHH
VSQQTYDRMKAERLAEAERLRARGREAAQRIRAVADRQVVETLAEARKESEILRGEGDAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
RSEIFAKSASEDPGFFAFYRSMAAYRRALETPDTTLVLSPDSEFFKFFRDAGGKLATPSQ
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]