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The map label for this gene is cobU [H]

Identifier: 23502184

GI number: 23502184

Start: 1269109

End: 1269630

Strand: Reverse

Name: cobU [H]

Synonym: BR1308

Alternate gene names: 23502184

Gene position: 1269630-1269109 (Counterclockwise)

Preceding gene: 23502185

Following gene: 23502183

Centisome position: 60.24

GC content: 60.15

Gene sequence:

>522_bases
ATGGCTTCGTCTGGAAAAAGCATTCTGGTTCTTGGCGGAGCGCGCTCGGGCAAGTCCTCCTATGCGGAAAAAATGGTTGA
AGCCTCGGGGCTTCAGCCGCTTTATCTGGCGACCGGACGCGCCTTCGACACCGAAATGGAAAGCCGCATCGCAATCCACC
GGGAAAGGCGCGGGCCGCAATGGCAAACGGTGGAGGAACCGCTTGATCTGGTGACGGCGCTTAAAGCCCACGCGGCGGCG
GGCCGGTTTGTGCTGGTCGATTGCCTGACGCTCTGGATCACCAATCTGATGATGGCGGAGCGGGATATGGCGGCGGAAAC
AGTCAGGCTTGTCGCCGCGCTGCCTGATCTGGCGGGGCCGGTGGTTTTTGTTTCCAACGAAGTTGGCCTTGGCATCGTGC
CGGAAAATCGCATGGCACGGGAATTTCGCGATCATGCGGGCTTTCTGCATCAGGCAGTGGCCGCGGCCGCGGACGAAGTT
TATTTTATGGCGGCGGGCCTGCCGCTCAAGATGAAGGGATAA

Upstream 100 bases:

>100_bases
CTTCGCTGGCGACCAACCTTTTCATGTGGGCGGTGATCGGGCTCGCGCTCGGCTGGTTCATCCAGCATTACGCATCCTCC
GAGATGGAAGGCTGACGAAC

Downstream 100 bases:

>100_bases
GTCATGCAGGGACAGAAAATTCCGGCAACGGTCATCACGGGTTTTCTCGGATCGGGCAAGACAACCATGATCCGCAACTT
GCTGGAAAATGCCAATGGCA

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MASSGKSILVLGGARSGKSSYAEKMVEASGLQPLYLATGRAFDTEMESRIAIHRERRGPQWQTVEEPLDLVTALKAHAAA
GRFVLVDCLTLWITNLMMAERDMAAETVRLVAALPDLAGPVVFVSNEVGLGIVPENRMAREFRDHAGFLHQAVAAAADEV
YFMAAGLPLKMKG

Sequences:

>Translated_173_residues
MASSGKSILVLGGARSGKSSYAEKMVEASGLQPLYLATGRAFDTEMESRIAIHRERRGPQWQTVEEPLDLVTALKAHAAA
GRFVLVDCLTLWITNLMMAERDMAAETVRLVAALPDLAGPVVFVSNEVGLGIVPENRMAREFRDHAGFLHQAVAAAADEV
YFMAAGLPLKMKG
>Mature_172_residues
ASSGKSILVLGGARSGKSSYAEKMVEASGLQPLYLATGRAFDTEMESRIAIHRERRGPQWQTVEEPLDLVTALKAHAAAG
RFVLVDCLTLWITNLMMAERDMAAETVRLVAALPDLAGPVVFVSNEVGLGIVPENRMAREFRDHAGFLHQAVAAAADEVY
FMAAGLPLKMKG

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=180, Percent_Identity=42.2222222222222, Blast_Score=131, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18670; Mature: 18539

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSGKSILVLGGARSGKSSYAEKMVEASGLQPLYLATGRAFDTEMESRIAIHRERRGPQ
CCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCC
WQTVEEPLDLVTALKAHAAAGRFVLVDCLTLWITNLMMAERDMAAETVRLVAALPDLAGP
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VVFVSNEVGLGIVPENRMAREFRDHAGFLHQAVAAAADEVYFMAAGLPLKMKG
EEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECC
>Mature Secondary Structure 
ASSGKSILVLGGARSGKSSYAEKMVEASGLQPLYLATGRAFDTEMESRIAIHRERRGPQ
CCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCC
WQTVEEPLDLVTALKAHAAAGRFVLVDCLTLWITNLMMAERDMAAETVRLVAALPDLAGP
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VVFVSNEVGLGIVPENRMAREFRDHAGFLHQAVAAAADEVYFMAAGLPLKMKG
EEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]