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The map label for this gene is cobW [H]

Identifier: 23502183

GI number: 23502183

Start: 1268056

End: 1269105

Strand: Reverse

Name: cobW [H]

Synonym: BR1307

Alternate gene names: 23502183

Gene position: 1269105-1268056 (Counterclockwise)

Preceding gene: 23502184

Following gene: 23502182

Centisome position: 60.21

GC content: 57.62

Gene sequence:

>1050_bases
ATGCAGGGACAGAAAATTCCGGCAACGGTCATCACGGGTTTTCTCGGATCGGGCAAGACAACCATGATCCGCAACTTGCT
GGAAAATGCCAATGGCAAGCGCATCGCACTGATTATCAACGAGTTCGGCGATCTCGGCGTCGATGGCGGCATTCTGAAAG
GCTGCGGGATCGAAACCTGCCGGGAGGAAGATGTCATCGAGCTCAATAATGGCTGCATCTGCTGCACCGTGGCCGATGAT
TTCATTCCGACCATGACAAAGCTTCTGGACCGGGAAGACCGGCCCGACCATATCGTGATCGAAACCTCCGGTCTTGCCTT
GCCGCAGCCGCTGGTGGCCGCCTTCAACTGGCCGGAGATCAAGACGCAGGTGACGGTTGATGGCGTGGTGACGGTGATCG
ATGCCGCCGCCGTGGCGGAAGGCCGTTTTGCCGACGACCATGACAAGGTGGATGCGCAGCGCGCAGCCGATGAATCTCTT
GACCATGAAAGCCCCTTGGAGGAACTTTTTGAGGATCAGATTCATGCCGCCGACCTCATTGTTCTCAACAAGGCCGACCT
GATCGATGCTGCGAAACTGGATAGCGTGAAGGCGGATGTGGCGGAGCGTTCGTCACGCCGGGTGAATATGGTGCCTGCAA
GCTTCGGCAAGCTTGGTGCGGATGTTCTGCTGGGGCTTGGCGTTGGGACGGAAGACGATATCGTCAACCGTCGCTCGCAT
CATGAAGCCCATCATGGAGACGGCCACGAGCATGATCATGACGAGTTTGAGAGTTTTGTGGTGGAGGCCGGTTCGGTTGC
CGATCCGAAGGCTTTTGCGGAAAAGCTGAAGGCTGTGATTGCCGAACACGATATTCTTCGCCTGAAGGGTTTTGTGGATG
TGCCGGGCAAGCCGATGCGCCTTGTGGTGCAGGCGGTGGGGCCGCGTATCGAACATTATTTCGACCGGCCATGGGGCAAG
GATGAAACACGCTCGACCCGGCTGGTGGTGATTGGCCTGCACGATATTGACGAAGCAGCCATCGCCCAGGCCGTGAAAGA
TGCCGCCTGA

Upstream 100 bases:

>100_bases
TCGCGATCATGCGGGCTTTCTGCATCAGGCAGTGGCCGCGGCCGCGGACGAAGTTTATTTTATGGCGGCGGGCCTGCCGC
TCAAGATGAAGGGATAAGTC

Downstream 100 bases:

>100_bases
TGCATCTCCTGCTTGCCCAGAAGGGAACGATCAGCGACGGCAATGAAGCCGTCGATCTTGGCCAGACGCCGGGTGAGATC
GTGTTTCTTTCCGCCGCCGA

Product: cobW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MQGQKIPATVITGFLGSGKTTMIRNLLENANGKRIALIINEFGDLGVDGGILKGCGIETCREEDVIELNNGCICCTVADD
FIPTMTKLLDREDRPDHIVIETSGLALPQPLVAAFNWPEIKTQVTVDGVVTVIDAAAVAEGRFADDHDKVDAQRAADESL
DHESPLEELFEDQIHAADLIVLNKADLIDAAKLDSVKADVAERSSRRVNMVPASFGKLGADVLLGLGVGTEDDIVNRRSH
HEAHHGDGHEHDHDEFESFVVEAGSVADPKAFAEKLKAVIAEHDILRLKGFVDVPGKPMRLVVQAVGPRIEHYFDRPWGK
DETRSTRLVVIGLHDIDEAAIAQAVKDAA

Sequences:

>Translated_349_residues
MQGQKIPATVITGFLGSGKTTMIRNLLENANGKRIALIINEFGDLGVDGGILKGCGIETCREEDVIELNNGCICCTVADD
FIPTMTKLLDREDRPDHIVIETSGLALPQPLVAAFNWPEIKTQVTVDGVVTVIDAAAVAEGRFADDHDKVDAQRAADESL
DHESPLEELFEDQIHAADLIVLNKADLIDAAKLDSVKADVAERSSRRVNMVPASFGKLGADVLLGLGVGTEDDIVNRRSH
HEAHHGDGHEHDHDEFESFVVEAGSVADPKAFAEKLKAVIAEHDILRLKGFVDVPGKPMRLVVQAVGPRIEHYFDRPWGK
DETRSTRLVVIGLHDIDEAAIAQAVKDAA
>Mature_349_residues
MQGQKIPATVITGFLGSGKTTMIRNLLENANGKRIALIINEFGDLGVDGGILKGCGIETCREEDVIELNNGCICCTVADD
FIPTMTKLLDREDRPDHIVIETSGLALPQPLVAAFNWPEIKTQVTVDGVVTVIDAAAVAEGRFADDHDKVDAQRAADESL
DHESPLEELFEDQIHAADLIVLNKADLIDAAKLDSVKADVAERSSRRVNMVPASFGKLGADVLLGLGVGTEDDIVNRRSH
HEAHHGDGHEHDHDEFESFVVEAGSVADPKAFAEKLKAVIAEHDILRLKGFVDVPGKPMRLVVQAVGPRIEHYFDRPWGK
DETRSTRLVVIGLHDIDEAAIAQAVKDAA

Specific function: Might be involved in cobalt reduction leading to cobalt(I) corrinoids [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=360, Percent_Identity=26.1111111111111, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI223941779, Length=361, Percent_Identity=26.8698060941828, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI126722884, Length=362, Percent_Identity=26.2430939226519, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI148727351, Length=362, Percent_Identity=26.2430939226519, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI146231952, Length=362, Percent_Identity=25.9668508287293, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI119120938, Length=137, Percent_Identity=36.4963503649635, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI223941776, Length=349, Percent_Identity=24.6418338108883, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI87082430, Length=343, Percent_Identity=29.7376093294461, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788499, Length=179, Percent_Identity=31.2849162011173, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324356, Length=222, Percent_Identity=30.1801801801802, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012824
- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 37830; Mature: 37830

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGQKIPATVITGFLGSGKTTMIRNLLENANGKRIALIINEFGDLGVDGGILKGCGIETC
CCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEECCCCCCCC
REEDVIELNNGCICCTVADDFIPTMTKLLDREDRPDHIVIETSGLALPQPLVAAFNWPEI
CCCCCEEECCCEEEEEECHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHCCCCCC
KTQVTVDGVVTVIDAAAVAEGRFADDHDKVDAQRAADESLDHESPLEELFEDQIHAADLI
EEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCEEE
VLNKADLIDAAKLDSVKADVAERSSRRVNMVPASFGKLGADVLLGLGVGTEDDIVNRRSH
EECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHCHHHHEECCCCCCHHHHCCHHH
HEAHHGDGHEHDHDEFESFVVEAGSVADPKAFAEKLKAVIAEHDILRLKGFVDVPGKPMR
CCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEECEECCCCCHHH
LVVQAVGPRIEHYFDRPWGKDETRSTRLVVIGLHDIDEAAIAQAVKDAA
HHHHHHCCHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MQGQKIPATVITGFLGSGKTTMIRNLLENANGKRIALIINEFGDLGVDGGILKGCGIETC
CCCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEECCCCCCCC
REEDVIELNNGCICCTVADDFIPTMTKLLDREDRPDHIVIETSGLALPQPLVAAFNWPEI
CCCCCEEECCCEEEEEECHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHCCCCCC
KTQVTVDGVVTVIDAAAVAEGRFADDHDKVDAQRAADESLDHESPLEELFEDQIHAADLI
EEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCEEE
VLNKADLIDAAKLDSVKADVAERSSRRVNMVPASFGKLGADVLLGLGVGTEDDIVNRRSH
EECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHCHHHHEECCCCCCHHHHCCHHH
HEAHHGDGHEHDHDEFESFVVEAGSVADPKAFAEKLKAVIAEHDILRLKGFVDVPGKPMR
CCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEECEECCCCCHHH
LVVQAVGPRIEHYFDRPWGKDETRSTRLVVIGLHDIDEAAIAQAVKDAA
HHHHHHCCHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697 [H]