Click here to switch to the map view.

The map label for this gene is glpX [H]

Identifier: 23502149

GI number: 23502149

Start: 1234600

End: 1235586

Strand: Reverse

Name: glpX [H]

Synonym: BR1273

Alternate gene names: 23502149

Gene position: 1235586-1234600 (Counterclockwise)

Preceding gene: 23502150

Following gene: 23502147

Centisome position: 58.62

GC content: 60.99

Gene sequence:

>987_bases
ATGGCCAAGACCGCAGAGCAGCACCCCCACGGGCTGGATCGCATTCTCACACTGGAGCTCGTCCGTGTGGCCGAGCGTGC
AGCCGTGGCGGCGGCAAGGCTGCGCGGGCGCGGCGATGAAATGGCTGCCGATCAGGCTGCTGTCGATGCCATGCGCCAGG
AATTGAACCGCCTGCCCATCACCGGGACAGTGGTGATTGGCGAGGGTGAGCGCGATGAAGCGCCGATGCTCTATATCGGC
GAGGAAGTCGGCACCAAGCAGGGGCCGGCTGTCGATATTGCACTGGACCCGCTGGAAGGCACCACGATCTGCGCCAAGAA
CCTGCCGAACTCGCTGGCGGTCATTGCCATTGCCGAAAAGGGCAACCTGCTTTACGCGCCTGACGTCTACATGGAAAAGA
TTGCTGTCGGCCCCGGCTATCCCAAGGGTGTCGTTGATCTCGATGCCACGCCGACGGACAACATCATGTCCATCGCCAAG
GCGAAGGGCGTGAAGCCGAATGAAATCACCGCCTGCATCATGGACCGCCCACGTCATGCGCGCCTTATCGAAGAAGTGCG
GGCGACCGGCGCTGCGATCCGCCTCATCGGCGACGGCGACGTGGCGGGCGTGATGCATACGACAGATCCGGACGAGACCG
GCATCGACATCTATATCGGCATTGGCGGTGCGCCTGAAGGTGTTCTGGCTGCTGCGGCGCTTCGCTGCATCGGTGGCCAG
ATGCAGGGCCGTTTGCAGCTCAATACCGAAGAGAAGGTTGCCCGTGCCGCCAAGATGGGTATTTCCGATCCGAAAAAGAT
CTATACCTTGGAGGAAATGGCCAAGGGCGATGTGCTCTTCGCGGCGACCGGCGTGACGGATGGCAATATGCTTTCCGGCG
TGAAATTCGCGCGGGATTATATCCAGACCCATACGATCGTGATGCGCTCGTCGTCGCAGACGGTGCGTGAAATCAAGGCG
CGCCATCAGGATTTGTCCAAATTCTAG

Upstream 100 bases:

>100_bases
GCTGTCGGGGACTTTGACAAAAGGTTTGAACAATGTCGCCATGGGGCGGCGATGGCGGCGATGCCGCATAAACGCAATTC
AAATTCAGGACTTTGTTCAA

Downstream 100 bases:

>100_bases
AGCATTTCCAGCAAAAGTGTGAAACGCCTACGCGGGGAAATCAGTCCACTGGACTGATTTCTGATCCCGCTTCGATGCGT
CGGAAAATGCGATAAAATAA

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MAKTAEQHPHGLDRILTLELVRVAERAAVAAARLRGRGDEMAADQAAVDAMRQELNRLPITGTVVIGEGERDEAPMLYIG
EEVGTKQGPAVDIALDPLEGTTICAKNLPNSLAVIAIAEKGNLLYAPDVYMEKIAVGPGYPKGVVDLDATPTDNIMSIAK
AKGVKPNEITACIMDRPRHARLIEEVRATGAAIRLIGDGDVAGVMHTTDPDETGIDIYIGIGGAPEGVLAAAALRCIGGQ
MQGRLQLNTEEKVARAAKMGISDPKKIYTLEEMAKGDVLFAATGVTDGNMLSGVKFARDYIQTHTIVMRSSSQTVREIKA
RHQDLSKF

Sequences:

>Translated_328_residues
MAKTAEQHPHGLDRILTLELVRVAERAAVAAARLRGRGDEMAADQAAVDAMRQELNRLPITGTVVIGEGERDEAPMLYIG
EEVGTKQGPAVDIALDPLEGTTICAKNLPNSLAVIAIAEKGNLLYAPDVYMEKIAVGPGYPKGVVDLDATPTDNIMSIAK
AKGVKPNEITACIMDRPRHARLIEEVRATGAAIRLIGDGDVAGVMHTTDPDETGIDIYIGIGGAPEGVLAAAALRCIGGQ
MQGRLQLNTEEKVARAAKMGISDPKKIYTLEEMAKGDVLFAATGVTDGNMLSGVKFARDYIQTHTIVMRSSSQTVREIKA
RHQDLSKF
>Mature_327_residues
AKTAEQHPHGLDRILTLELVRVAERAAVAAARLRGRGDEMAADQAAVDAMRQELNRLPITGTVVIGEGERDEAPMLYIGE
EVGTKQGPAVDIALDPLEGTTICAKNLPNSLAVIAIAEKGNLLYAPDVYMEKIAVGPGYPKGVVDLDATPTDNIMSIAKA
KGVKPNEITACIMDRPRHARLIEEVRATGAAIRLIGDGDVAGVMHTTDPDETGIDIYIGIGGAPEGVLAAAALRCIGGQM
QGRLQLNTEEKVARAAKMGISDPKKIYTLEEMAKGDVLFAATGVTDGNMLSGVKFARDYIQTHTIVMRSSSQTVREIKAR
HQDLSKF

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=323, Percent_Identity=46.1300309597523, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1789298, Length=322, Percent_Identity=41.304347826087, Blast_Score=221, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 34975; Mature: 34844

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTAEQHPHGLDRILTLELVRVAERAAVAAARLRGRGDEMAADQAAVDAMRQELNRLPI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
TGTVVIGEGERDEAPMLYIGEEVGTKQGPAVDIALDPLEGTTICAKNLPNSLAVIAIAEK
EEEEEEECCCCCCCCEEEECHHHCCCCCCEEEEEECCCCCCEEECCCCCCCEEEEEEECC
GNLLYAPDVYMEKIAVGPGYPKGVVDLDATPTDNIMSIAKAKGVKPNEITACIMDRPRHA
CCEEECCCHHHHHEECCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHH
RLIEEVRATGAAIRLIGDGDVAGVMHTTDPDETGIDIYIGIGGAPEGVLAAAALRCIGGQ
HHHHHHHCCCEEEEEEECCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCC
MQGRLQLNTEEKVARAAKMGISDPKKIYTLEEMAKGDVLFAATGVTDGNMLSGVKFARDY
CCCEEEECHHHHHHHHHHCCCCCCHHEEEHHHHCCCCEEEEEECCCCCCHHHHHHHHHHH
IQTHTIVMRSSSQTVREIKARHQDLSKF
HHHEEEEEECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKTAEQHPHGLDRILTLELVRVAERAAVAAARLRGRGDEMAADQAAVDAMRQELNRLPI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
TGTVVIGEGERDEAPMLYIGEEVGTKQGPAVDIALDPLEGTTICAKNLPNSLAVIAIAEK
EEEEEEECCCCCCCCEEEECHHHCCCCCCEEEEEECCCCCCEEECCCCCCCEEEEEEECC
GNLLYAPDVYMEKIAVGPGYPKGVVDLDATPTDNIMSIAKAKGVKPNEITACIMDRPRHA
CCEEECCCHHHHHEECCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHH
RLIEEVRATGAAIRLIGDGDVAGVMHTTDPDETGIDIYIGIGGAPEGVLAAAALRCIGGQ
HHHHHHHCCCEEEEEEECCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCC
MQGRLQLNTEEKVARAAKMGISDPKKIYTLEEMAKGDVLFAATGVTDGNMLSGVKFARDY
CCCEEEECHHHHHHHHHHCCCCCCHHEEEHHHHCCCCEEEEEECCCCCCHHHHHHHHHHH
IQTHTIVMRSSSQTVREIKARHQDLSKF
HHHEEEEEECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]