Click here to switch to the map view.

The map label for this gene is feaR [H]

Identifier: 23501439

GI number: 23501439

Start: 545638

End: 546708

Strand: Reverse

Name: feaR [H]

Synonym: BR0550

Alternate gene names: 23501439

Gene position: 546708-545638 (Counterclockwise)

Preceding gene: 23501440

Following gene: 23501438

Centisome position: 25.94

GC content: 57.8

Gene sequence:

>1071_bases
ATGAACAGAGAGCTGTTTCTGTCAACAGATATGGTGGATGCAACGCAGCGCGACGACTTCTGGCGCGAAGCGGTAAAGCT
CATCTATGATGTCATGTCCTCGGATGACCAAAGCGGCAAAGGCTTCAAAGGCACCTTGCGGTCACAACAGTTCGGCACAT
GCCTGATCGGCTCGGCCACCTCTAACGGGCAGAACTACCAGCGCACGCCGAGCATCATCGCCCAAAGCGACATGGACCAT
TATGTCCTGCAGGCCATGATCGCTGGCAGAATGACCGGCGATTTCAACGGCACAAATGTCAGCGCCAAGCCCGGCGACAT
TGTCATCCTCGATCTTTTGCAAACCGTTTCAAGCAGTGTGGAAGCAGGAGAGCGCATCACGATCGTCATCCAGCGCGGGG
AGCTGGAAAAGCTCGTGGGCTGGCGCAATCTTCACGGCATGGTGCTGCCGGGCGAAGCGCCCACCACACGGCTGCTGTTT
GAATATCTGCGCGGGCTGGATGCGGTCGCCGCCGAATTGCCGCCCAATGAGGCACTTGCCGCGCAGGAAGCAATGCTCAC
CCTGCTTTCAGCGAGTATCACCAGCAAGGAGGAAGAAGCCATCGAAAACACGCCGGCCAATCTTCCCATGCGCCATCGCA
TCATAACCTATATCGATGAAAACCTCACCAATCCGCTGCTGGGGCCGCATTCGATCATGCAGCATTTCCACTTGTCGCGC
TCGCATCTTTATCGCGCTTTCGAGCCGGATGGCGGCGTTGCAAAGGTCATCCGCGACAAGCGGCTGGACCTCGCCTACCG
CATTTTGATCGACCGCAAGGGCAAGCCGACCTCGCTGAAGGAAATCGCCTATTGCTGCGGCTTCAATGACAGGACGCAGT
TCACCAAGGCATTCAAGGCGCGTTTCGAGCTTTCACCGAAGGAAGCGCGCGAAATCGGCGCTCCGCTGCCGCAAGCTCCA
AGCGGCGCACTCATCCTGCACAGCCATCTTTCAGAACAGGCTGCCAAGATCGCCTCTGAACACGCGACCACCAGCACAAA
AGCACCACCCAGCGCACCGGTAAAACCCTGA

Upstream 100 bases:

>100_bases
AAATAACATTTATTTTTCCGGATCATCCTTAATGACGCTTCCCGCGCGTTATTCAAAACTAAACTTTGGAACGTATCAGC
ACTGGGCATGAAAGATCGAA

Downstream 100 bases:

>100_bases
CGGCCTCCAGGGCAGGCGCAATATCGAGCGCAGGCACGCCGTTTGAGGAATACACAGGATCGTTTCATTGGCGGACATAT
CTCCATTCCTCACCGCCCGA

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MNRELFLSTDMVDATQRDDFWREAVKLIYDVMSSDDQSGKGFKGTLRSQQFGTCLIGSATSNGQNYQRTPSIIAQSDMDH
YVLQAMIAGRMTGDFNGTNVSAKPGDIVILDLLQTVSSSVEAGERITIVIQRGELEKLVGWRNLHGMVLPGEAPTTRLLF
EYLRGLDAVAAELPPNEALAAQEAMLTLLSASITSKEEEAIENTPANLPMRHRIITYIDENLTNPLLGPHSIMQHFHLSR
SHLYRAFEPDGGVAKVIRDKRLDLAYRILIDRKGKPTSLKEIAYCCGFNDRTQFTKAFKARFELSPKEAREIGAPLPQAP
SGALILHSHLSEQAAKIASEHATTSTKAPPSAPVKP

Sequences:

>Translated_356_residues
MNRELFLSTDMVDATQRDDFWREAVKLIYDVMSSDDQSGKGFKGTLRSQQFGTCLIGSATSNGQNYQRTPSIIAQSDMDH
YVLQAMIAGRMTGDFNGTNVSAKPGDIVILDLLQTVSSSVEAGERITIVIQRGELEKLVGWRNLHGMVLPGEAPTTRLLF
EYLRGLDAVAAELPPNEALAAQEAMLTLLSASITSKEEEAIENTPANLPMRHRIITYIDENLTNPLLGPHSIMQHFHLSR
SHLYRAFEPDGGVAKVIRDKRLDLAYRILIDRKGKPTSLKEIAYCCGFNDRTQFTKAFKARFELSPKEAREIGAPLPQAP
SGALILHSHLSEQAAKIASEHATTSTKAPPSAPVKP
>Mature_356_residues
MNRELFLSTDMVDATQRDDFWREAVKLIYDVMSSDDQSGKGFKGTLRSQQFGTCLIGSATSNGQNYQRTPSIIAQSDMDH
YVLQAMIAGRMTGDFNGTNVSAKPGDIVILDLLQTVSSSVEAGERITIVIQRGELEKLVGWRNLHGMVLPGEAPTTRLLF
EYLRGLDAVAAELPPNEALAAQEAMLTLLSASITSKEEEAIENTPANLPMRHRIITYIDENLTNPLLGPHSIMQHFHLSR
SHLYRAFEPDGGVAKVIRDKRLDLAYRILIDRKGKPTSLKEIAYCCGFNDRTQFTKAFKARFELSPKEAREIGAPLPQAP
SGALILHSHLSEQAAKIASEHATTSTKAPPSAPVKP

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=291, Percent_Identity=25.7731958762887, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 39213; Mature: 39213

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRELFLSTDMVDATQRDDFWREAVKLIYDVMSSDDQSGKGFKGTLRSQQFGTCLIGSAT
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCC
SNGQNYQRTPSIIAQSDMDHYVLQAMIAGRMTGDFNGTNVSAKPGDIVILDLLQTVSSSV
CCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHH
EAGERITIVIQRGELEKLVGWRNLHGMVLPGEAPTTRLLFEYLRGLDAVAAELPPNEALA
CCCCEEEEEEECCCHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
AQEAMLTLLSASITSKEEEAIENTPANLPMRHRIITYIDENLTNPLLGPHSIMQHFHLSR
HHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCH
SHLYRAFEPDGGVAKVIRDKRLDLAYRILIDRKGKPTSLKEIAYCCGFNDRTQFTKAFKA
HHHHEEECCCCCHHHHHHHHHHCEEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHH
RFELSPKEAREIGAPLPQAPSGALILHSHLSEQAAKIASEHATTSTKAPPSAPVKP
HHCCCHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRELFLSTDMVDATQRDDFWREAVKLIYDVMSSDDQSGKGFKGTLRSQQFGTCLIGSAT
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCC
SNGQNYQRTPSIIAQSDMDHYVLQAMIAGRMTGDFNGTNVSAKPGDIVILDLLQTVSSSV
CCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHH
EAGERITIVIQRGELEKLVGWRNLHGMVLPGEAPTTRLLFEYLRGLDAVAAELPPNEALA
CCCCEEEEEEECCCHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
AQEAMLTLLSASITSKEEEAIENTPANLPMRHRIITYIDENLTNPLLGPHSIMQHFHLSR
HHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCH
SHLYRAFEPDGGVAKVIRDKRLDLAYRILIDRKGKPTSLKEIAYCCGFNDRTQFTKAFKA
HHHHEEECCCCCHHHHHHHHHHCEEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHH
RFELSPKEAREIGAPLPQAPSGALILHSHLSEQAAKIASEHATTSTKAPPSAPVKP
HHCCCHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]