Click here to switch to the map view.

The map label for this gene is kdgR [H]

Identifier: 23501141

GI number: 23501141

Start: 246171

End: 246965

Strand: Reverse

Name: kdgR [H]

Synonym: BR0234

Alternate gene names: 23501141

Gene position: 246965-246171 (Counterclockwise)

Preceding gene: 23501153

Following gene: 23501140

Centisome position: 11.72

GC content: 60.38

Gene sequence:

>795_bases
ATGAGGGAGCCGACCTTGGAAACTGACGATCGCTATCGCGCGCCCGCGCTGGACAAGGGGCTGGACATATTGGAATTGCT
GGCGAGTGTGGATGGCGGGCTGACACAGGCCGAGATCGCCAAGCATCTCGACCGCAGCCCCAACGAATTTTACCGGATGC
TGGACCGGCTGGTGAAGCGCGGCTATGTCACCAAACTCGATGGCGACCGTTATTCACTGACGCTGAAGCTGTTCGGGCTT
GCGCAACTCCATGCGCCGGTGCGCAGGCTTGCCTCCTTCGCCACGCCCTTCATGCGCGAGCTTGCCGACCGTTCCAAACA
GGCCAATCAGCTTGCCGTGTTCGACCGCGGCTCGGTGGTGGTCATCGCTCAGCAGGAAGCACCGGATTACTGGGGCATTT
CCATCCGCGTCGGCTCGCATATCAGCCTGTTCGATACCGGCTCCGGTCACGTTCTGCTCGCCTTCCGCTCACCGGAAGAG
CGCGAAATGATGATTGCCGCCCATGTGAAAAGCCGTGATGAAGTCAATCTGGATCAGGACTTCTATGACCGTCTCGACCA
GATACGCGAGCGCGGATACGAGATGATGGCGAGCGCACAGATGGCGGGCGCCTATAATCTTTCCGCGCCGATCCTCGGCC
CGGACGGCACCTGCATTGCAGCCCTCACCTGCCCCTATATCACGCTCGTCAATCCGTCTTCGGCCCCTGATATCACCCAG
ACGATCAGCCTGTTGCAGAAGACGGTACGCGACCTCTCCAAGCTGGTGGGCGCGGATGTAGGCGTGACAGGATAA

Upstream 100 bases:

>100_bases
CCATTTATATGCAAACATATTATTCAAACATGGTCAAGGCGATTTGCGGGTGGTTATTCCTTTCACCCTTTACGCTGTTC
GTATATGAAGAAAGCCATTT

Downstream 100 bases:

>100_bases
ATTCTGATTTGAAAAATATCTTCTTTTTTGAAAGCATCGAAAGCAAGGAGGATTCCCATGCTGATCGATACGCACCTGCA
CCTGATCGACAAAAACGCGC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MREPTLETDDRYRAPALDKGLDILELLASVDGGLTQAEIAKHLDRSPNEFYRMLDRLVKRGYVTKLDGDRYSLTLKLFGL
AQLHAPVRRLASFATPFMRELADRSKQANQLAVFDRGSVVVIAQQEAPDYWGISIRVGSHISLFDTGSGHVLLAFRSPEE
REMMIAAHVKSRDEVNLDQDFYDRLDQIRERGYEMMASAQMAGAYNLSAPILGPDGTCIAALTCPYITLVNPSSAPDITQ
TISLLQKTVRDLSKLVGADVGVTG

Sequences:

>Translated_264_residues
MREPTLETDDRYRAPALDKGLDILELLASVDGGLTQAEIAKHLDRSPNEFYRMLDRLVKRGYVTKLDGDRYSLTLKLFGL
AQLHAPVRRLASFATPFMRELADRSKQANQLAVFDRGSVVVIAQQEAPDYWGISIRVGSHISLFDTGSGHVLLAFRSPEE
REMMIAAHVKSRDEVNLDQDFYDRLDQIRERGYEMMASAQMAGAYNLSAPILGPDGTCIAALTCPYITLVNPSSAPDITQ
TISLLQKTVRDLSKLVGADVGVTG
>Mature_264_residues
MREPTLETDDRYRAPALDKGLDILELLASVDGGLTQAEIAKHLDRSPNEFYRMLDRLVKRGYVTKLDGDRYSLTLKLFGL
AQLHAPVRRLASFATPFMRELADRSKQANQLAVFDRGSVVVIAQQEAPDYWGISIRVGSHISLFDTGSGHVLLAFRSPEE
REMMIAAHVKSRDEVNLDQDFYDRLDQIRERGYEMMASAQMAGAYNLSAPILGPDGTCIAALTCPYITLVNPSSAPDITQ
TISLLQKTVRDLSKLVGADVGVTG

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=225, Percent_Identity=28, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786715, Length=253, Percent_Identity=26.0869565217391, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29217; Mature: 29217

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREPTLETDDRYRAPALDKGLDILELLASVDGGLTQAEIAKHLDRSPNEFYRMLDRLVKR
CCCCCCCCCCCCCCCCHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHC
GYVTKLDGDRYSLTLKLFGLAQLHAPVRRLASFATPFMRELADRSKQANQLAVFDRGSVV
CCEEEECCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEE
VIAQQEAPDYWGISIRVGSHISLFDTGSGHVLLAFRSPEEREMMIAAHVKSRDEVNLDQD
EEEECCCCCEEEEEEEECCEEEEEECCCCEEEEEECCCCHHHEEEEEECCCCCCCCCCHH
FYDRLDQIRERGYEMMASAQMAGAYNLSAPILGPDGTCIAALTCPYITLVNPSSAPDITQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCCHHHH
TISLLQKTVRDLSKLVGADVGVTG
HHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MREPTLETDDRYRAPALDKGLDILELLASVDGGLTQAEIAKHLDRSPNEFYRMLDRLVKR
CCCCCCCCCCCCCCCCHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHC
GYVTKLDGDRYSLTLKLFGLAQLHAPVRRLASFATPFMRELADRSKQANQLAVFDRGSVV
CCEEEECCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEE
VIAQQEAPDYWGISIRVGSHISLFDTGSGHVLLAFRSPEEREMMIAAHVKSRDEVNLDQD
EEEECCCCCEEEEEEEECCEEEEEECCCCEEEEEECCCCHHHEEEEEECCCCCCCCCCHH
FYDRLDQIRERGYEMMASAQMAGAYNLSAPILGPDGTCIAALTCPYITLVNPSSAPDITQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCCHHHH
TISLLQKTVRDLSKLVGADVGVTG
HHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]