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The map label for this gene is ribB

Identifier: 23100669

GI number: 23100669

Start: 3346761

End: 3347384

Strand: Reverse

Name: ribB

Synonym: OB3214

Alternate gene names: 23100669

Gene position: 3347384-3346761 (Counterclockwise)

Preceding gene: 23100670

Following gene: 23100668

Centisome position: 92.2

GC content: 40.54

Gene sequence:

>624_bases
ATGAACGAGCTAAGCAAGATAGAGCAAGCGATCGAAGATTTACGAAACGGAAAGTTGATTATTGTTGCGGATGATGCGGA
CCGAGAAGCAGAAGGAGATCTTGTTGGGCTAAGCGAATTTGTAACGCCTGAAAAAGTTAATTTTATGACGAAATACGGAC
GAGGATTAATCTGTGTTCCTATCACAGAAGAACGAGCGCTGGAATTAGATTTACATGCAATGGCTACAAACAACACGGAT
ACGTATGGAACTCAATTTACGGTTAGTGTTGATTATTATACCAATTCTACAGGGATATCTACCGCTGATCGTGCAGATAC
GATACGAGCTTTAGCTGAACCATTATCAAAAGCGGCAGATTTCAAGCGTCCGGGTCATATGTTTCCGCTAATCGCGAAAA
ATGCAGGTGTATTGGAACGTAGAGGTCACACAGAAGCAGCTGTTGATTTGGCTAGACTATCCAATTCGATTCCTTCGGCA
TATATTTGTGAAATTTTAAATGATGATGGGACGATGGCAAGATATCCTGCGCTTGAAACACTTGCAAAAGACTGGGATTT
GACCTTGATTACAGTAGAAGATCTCGTTCAATATCGAGAAAAAGAAATAGCTATCGAAAATTAA

Upstream 100 bases:

>100_bases
ATATGGAGACAGATATGCTTGCTAAATATATTCTTCAAGCAAATAAGCAAACCTTATCACAGTCCTTTTTACAAGAGAAT
GGATTTTAAGGAGGGTAAAT

Downstream 100 bases:

>100_bases
TCTTAAAGGAGTTTGATCATATGACAATTTATGAAGGCAACTATAATGGACAGGGCAAGAAGATAGCGATTGTAACAAGT
AGATTTAATGAATTTATTAC

Product: truncated 3, 4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MNELSKIEQAIEDLRNGKLIIVADDADREAEGDLVGLSEFVTPEKVNFMTKYGRGLICVPITEERALELDLHAMATNNTD
TYGTQFTVSVDYYTNSTGISTADRADTIRALAEPLSKAADFKRPGHMFPLIAKNAGVLERRGHTEAAVDLARLSNSIPSA
YICEILNDDGTMARYPALETLAKDWDLTLITVEDLVQYREKEIAIEN

Sequences:

>Translated_207_residues
MNELSKIEQAIEDLRNGKLIIVADDADREAEGDLVGLSEFVTPEKVNFMTKYGRGLICVPITEERALELDLHAMATNNTD
TYGTQFTVSVDYYTNSTGISTADRADTIRALAEPLSKAADFKRPGHMFPLIAKNAGVLERRGHTEAAVDLARLSNSIPSA
YICEILNDDGTMARYPALETLAKDWDLTLITVEDLVQYREKEIAIEN
>Mature_207_residues
MNELSKIEQAIEDLRNGKLIIVADDADREAEGDLVGLSEFVTPEKVNFMTKYGRGLICVPITEERALELDLHAMATNNTD
TYGTQFTVSVDYYTNSTGISTADRADTIRALAEPLSKAADFKRPGHMFPLIAKNAGVLERRGHTEAAVDLARLSNSIPSA
YICEILNDDGTMARYPALETLAKDWDLTLITVEDLVQYREKEIAIEN

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family

Homologues:

Organism=Escherichia coli, GI1789420, Length=198, Percent_Identity=44.9494949494949, Blast_Score=184, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6320695, Length=207, Percent_Identity=43.4782608695652, Blast_Score=167, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIBB_OCEIH (Q8CWF6)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_694136.1
- ProteinModelPortal:   Q8CWF6
- SMR:   Q8CWF6
- GeneID:   1018065
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB3214
- NMPDR:   fig|221109.1.peg.3216
- HOGENOM:   HBG735778
- OMA:   RGHTEAT
- BioCyc:   OIHE221109:OB3214-MONOMER
- BRENDA:   4.1.99.12
- HAMAP:   MF_00180
- InterPro:   IPR017945
- InterPro:   IPR000422
- Gene3D:   G3DSA:3.90.870.10
- TIGRFAMs:   TIGR00506

Pfam domain/function: PF00926 DHBP_synthase; SSF55821 DHBP_synth_RibB-like_a/b_dom

EC number: =4.1.99.12

Molecular weight: Translated: 22928; Mature: 22928

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: BINDING 33-33 BINDING 164-164

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELSKIEQAIEDLRNGKLIIVADDADREAEGDLVGLSEFVTPEKVNFMTKYGRGLICVP
CCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEECHHHHCCCHHHHHHHHHCCCEEEEE
ITEERALELDLHAMATNNTDTYGTQFTVSVDYYTNSTGISTADRADTIRALAEPLSKAAD
ECCCCEEEEEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHC
FKRPGHMFPLIAKNAGVLERRGHTEAAVDLARLSNSIPSAYICEILNDDGTMARYPALET
CCCCCCCCEEEECCCCCHHHCCCHHHHHHHHHHHCCCCHHHHHEEECCCCCEECCCHHHH
LAKDWDLTLITVEDLVQYREKEIAIEN
HHCCCCEEEEEHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNELSKIEQAIEDLRNGKLIIVADDADREAEGDLVGLSEFVTPEKVNFMTKYGRGLICVP
CCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEECHHHHCCCHHHHHHHHHCCCEEEEE
ITEERALELDLHAMATNNTDTYGTQFTVSVDYYTNSTGISTADRADTIRALAEPLSKAAD
ECCCCEEEEEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHC
FKRPGHMFPLIAKNAGVLERRGHTEAAVDLARLSNSIPSAYICEILNDDGTMARYPALET
CCCCCCCCEEEECCCCCHHHCCCHHHHHHHHHHHCCCCHHHHHEEECCCCCEECCCHHHH
LAKDWDLTLITVEDLVQYREKEIAIEN
HHCCCCEEEEEHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12235376