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The map label for this gene is cidA2 [H]

Identifier: 23100587

GI number: 23100587

Start: 3265404

End: 3265781

Strand: Reverse

Name: cidA2 [H]

Synonym: OB3132

Alternate gene names: 23100587

Gene position: 3265781-3265404 (Counterclockwise)

Preceding gene: 23100588

Following gene: 23100586

Centisome position: 89.95

GC content: 31.48

Gene sequence:

>378_bases
ATGAAGGTGGTTTACGTTGGAAAAGTAATTATACATACGTTATTACTTATTGTTTTATATCAAATGGGAACATGGATTCA
TGATTTTTTAAATTTAACCCTACCAGGTAGTGTTATTGGAATGATTTTATTATTTGTTTTATTAATTACCGGATTAGTCA
AACCGTCATGGGTAGACCAAGGAGCATTACTCTTAGTAAAACATTTACCATTATTTTTTATTCCTGCAACAGTAGGTATT
ATTTCTTTTCTCCATCTTTTTGCAGGCAGTGGCATTTTTTTAATAGCGATTATCATTGTTAGTACAGCGTTAGTGATTGT
GATATCTGGACATGTTAGCCAGTGGTTAGTTAGGAAGAAGGAATTAAAGCATGATTAA

Upstream 100 bases:

>100_bases
GTTTCAACTTAAAACAATAAGGTGAGACCTCATACATTAGTTTATAGAGGCTCACCATTTGTTTTAAGTCTGATTGTAAG
GGTGAAGGAAAGGAACAGTG

Downstream 100 bases:

>100_bases
TTCATTATTGACGATTGTGTTTATCATTGGCACATTGTCTATATATATTTTGTCACGAAAACTAAATAAGAAATGGAATC
ATCCACTGACATTACCTGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MKVVYVGKVIIHTLLLIVLYQMGTWIHDFLNLTLPGSVIGMILLFVLLITGLVKPSWVDQGALLLVKHLPLFFIPATVGI
ISFLHLFAGSGIFLIAIIIVSTALVIVISGHVSQWLVRKKELKHD

Sequences:

>Translated_125_residues
MKVVYVGKVIIHTLLLIVLYQMGTWIHDFLNLTLPGSVIGMILLFVLLITGLVKPSWVDQGALLLVKHLPLFFIPATVGI
ISFLHLFAGSGIFLIAIIIVSTALVIVISGHVSQWLVRKKELKHD
>Mature_125_residues
MKVVYVGKVIIHTLLLIVLYQMGTWIHDFLNLTLPGSVIGMILLFVLLITGLVKPSWVDQGALLLVKHLPLFFIPATVGI
ISFLHLFAGSGIFLIAIIIVSTALVIVISGHVSQWLVRKKELKHD

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 13819; Mature: 13819

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVYVGKVIIHTLLLIVLYQMGTWIHDFLNLTLPGSVIGMILLFVLLITGLVKPSWVDQ
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
GALLLVKHLPLFFIPATVGIISFLHLFAGSGIFLIAIIIVSTALVIVISGHVSQWLVRKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELKHD
HHCCC
>Mature Secondary Structure
MKVVYVGKVIIHTLLLIVLYQMGTWIHDFLNLTLPGSVIGMILLFVLLITGLVKPSWVDQ
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
GALLLVKHLPLFFIPATVGIISFLHLFAGSGIFLIAIIIVSTALVIVISGHVSQWLVRKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELKHD
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]