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The map label for this gene is glpX [H]

Identifier: 23100457

GI number: 23100457

Start: 3110737

End: 3111714

Strand: Reverse

Name: glpX [H]

Synonym: OB3002

Alternate gene names: 23100457

Gene position: 3111714-3110737 (Counterclockwise)

Preceding gene: 23100458

Following gene: 23100456

Centisome position: 85.71

GC content: 40.59

Gene sequence:

>978_bases
ATGTTTGAAATGGAAAGAAGTTTATCAATGGAACTAGTACGTGTAACCGAGGCGGCAGCATTACAATCTGCTCGTTGGAT
GGGTAGAGGAGTAAAAGATGAAGCTGATGACGCTGCAACTACTGCGATGCGTACGGTGTTTGATACCATTCCAATGGAAG
GTACCGTAGTAATTGGCGAAGGAGAAATGGACGAAGCCCCAATGCTTTATATTGGAGAAAAGTTAGGCACTGGGGACGGT
CCAGGAGTAGATGTTGCCGTAGATCCATTAGAAGGTACTGAAATAGTTGCTCAAGGAACGTGGAATGCCCTAGCTGTTAT
TGCTATTGCAGATAGAGGGACATTACTGCATGCGCCAGATATGTATATGGAAAAAATTGCAGTAGGCCCCGATGCGATAG
GTAAAATTGATATAAATGCTCCAGTAGTTGATAACCTTAAAGCAGTAGCAAAGGCAAAAAATAAATCGATTGAAGATGTA
GTAGCTACAGTTCTTGATCGCCCACGTCATCAAAAACTTATAGATAAAATTCGTGCTTCTGGTGCAAGAATTAAATTGAT
TCCTAATGGAGATGTAGCAGCAGCAATCAATACTGCTTTTGATGATACAGGTGTGGATATACTATTAGGATCTGGTGGTG
CACCAGAGGGTGTTTTAGCAGCTGCAGCGTTAAAATGTTTAGGTGGAGAACTTCAAGGGAAGTTAGTACCATCGAATGAT
GATGAAATTAAACGATGTCATGATATGGGTATCACTGATTTAAATAAAGTATTTTACATGAATGACTTTTGTAGCGGAGA
CGATGCTATTTTTGCAGCCACTGGTGTTACAGATGGAGAGTTATTAAAAGGAGTTCAGTTTAAAGGGAAGAAAGCAACAA
CTTCTACGTTAGTAATGCGTGCGAGAAGTGGAACTGTTCGTTTCATTGATGGAACTCATAGTTTGCAGAAAAAACCGGAT
CTCGTAATCAAGCCATAA

Upstream 100 bases:

>100_bases
TATCCATTTCACACATTAACTATTACTTAATGGGATGAGTATAGGTAGATGTGTTCAAAAAGGTAGAATTTTTGACCATC
CTCTAATAAAGGAAAGGGAG

Downstream 100 bases:

>100_bases
TTTAAATAAAGAAGATGTTTCCCAAAAATAATTTGTTTTGATAGATTTTTTAATGTCTATAAAAAATTCAATCGACATAT
TTTTGGGGACAACTTCTACA

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MFEMERSLSMELVRVTEAAALQSARWMGRGVKDEADDAATTAMRTVFDTIPMEGTVVIGEGEMDEAPMLYIGEKLGTGDG
PGVDVAVDPLEGTEIVAQGTWNALAVIAIADRGTLLHAPDMYMEKIAVGPDAIGKIDINAPVVDNLKAVAKAKNKSIEDV
VATVLDRPRHQKLIDKIRASGARIKLIPNGDVAAAINTAFDDTGVDILLGSGGAPEGVLAAAALKCLGGELQGKLVPSND
DEIKRCHDMGITDLNKVFYMNDFCSGDDAIFAATGVTDGELLKGVQFKGKKATTSTLVMRARSGTVRFIDGTHSLQKKPD
LVIKP

Sequences:

>Translated_325_residues
MFEMERSLSMELVRVTEAAALQSARWMGRGVKDEADDAATTAMRTVFDTIPMEGTVVIGEGEMDEAPMLYIGEKLGTGDG
PGVDVAVDPLEGTEIVAQGTWNALAVIAIADRGTLLHAPDMYMEKIAVGPDAIGKIDINAPVVDNLKAVAKAKNKSIEDV
VATVLDRPRHQKLIDKIRASGARIKLIPNGDVAAAINTAFDDTGVDILLGSGGAPEGVLAAAALKCLGGELQGKLVPSND
DEIKRCHDMGITDLNKVFYMNDFCSGDDAIFAATGVTDGELLKGVQFKGKKATTSTLVMRARSGTVRFIDGTHSLQKKPD
LVIKP
>Mature_325_residues
MFEMERSLSMELVRVTEAAALQSARWMGRGVKDEADDAATTAMRTVFDTIPMEGTVVIGEGEMDEAPMLYIGEKLGTGDG
PGVDVAVDPLEGTEIVAQGTWNALAVIAIADRGTLLHAPDMYMEKIAVGPDAIGKIDINAPVVDNLKAVAKAKNKSIEDV
VATVLDRPRHQKLIDKIRASGARIKLIPNGDVAAAINTAFDDTGVDILLGSGGAPEGVLAAAALKCLGGELQGKLVPSND
DEIKRCHDMGITDLNKVFYMNDFCSGDDAIFAATGVTDGELLKGVQFKGKKATTSTLVMRARSGTVRFIDGTHSLQKKPD
LVIKP

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=328, Percent_Identity=49.0853658536585, Blast_Score=318, Evalue=2e-88,
Organism=Escherichia coli, GI1789298, Length=320, Percent_Identity=44.6875, Blast_Score=265, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 34406; Mature: 34406

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEMERSLSMELVRVTEAAALQSARWMGRGVKDEADDAATTAMRTVFDTIPMEGTVVIGE
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEC
GEMDEAPMLYIGEKLGTGDGPGVDVAVDPLEGTEIVAQGTWNALAVIAIADRGTLLHAPD
CCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCEEEEECCCCEEEEEEEECCCCEEECCH
MYMEKIAVGPDAIGKIDINAPVVDNLKAVAKAKNKSIEDVVATVLDRPRHQKLIDKIRAS
HHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCC
GARIKLIPNGDVAAAINTAFDDTGVDILLGSGGAPEGVLAAAALKCLGGELQGKLVPSND
CCEEEEEECCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEECCCC
DEIKRCHDMGITDLNKVFYMNDFCSGDDAIFAATGVTDGELLKGVQFKGKKATTSTLVMR
HHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEECCCCCHHHHCCCCCCCCCCCCEEEEEE
ARSGTVRFIDGTHSLQKKPDLVIKP
ECCCEEEEEECCCCCCCCCCEEECC
>Mature Secondary Structure
MFEMERSLSMELVRVTEAAALQSARWMGRGVKDEADDAATTAMRTVFDTIPMEGTVVIGE
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEC
GEMDEAPMLYIGEKLGTGDGPGVDVAVDPLEGTEIVAQGTWNALAVIAIADRGTLLHAPD
CCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCEEEEECCCCEEEEEEEECCCCEEECCH
MYMEKIAVGPDAIGKIDINAPVVDNLKAVAKAKNKSIEDVVATVLDRPRHQKLIDKIRAS
HHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCC
GARIKLIPNGDVAAAINTAFDDTGVDILLGSGGAPEGVLAAAALKCLGGELQGKLVPSND
CCEEEEEECCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEECCCC
DEIKRCHDMGITDLNKVFYMNDFCSGDDAIFAATGVTDGELLKGVQFKGKKATTSTLVMR
HHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEECCCCCHHHHCCCCCCCCCCCCEEEEEE
ARSGTVRFIDGTHSLQKKPDLVIKP
ECCCEEEEEECCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]