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The map label for this gene is murZ

Identifier: 23100458

GI number: 23100458

Start: 3111816

End: 3113102

Strand: Reverse

Name: murZ

Synonym: OB3003

Alternate gene names: 23100458

Gene position: 3113102-3111816 (Counterclockwise)

Preceding gene: 23100459

Following gene: 23100457

Centisome position: 85.75

GC content: 38.93

Gene sequence:

>1287_bases
ATGCAAAAATTATTAATTGAAGGTGGTCATGATCTAACTGGCCAAGTTCGAATTAGTGGAGCCAAGAACAGTGCGGTTGC
TTTACTTCCTGCTGCAATATTGGCGGATTCAGCCGTGACGATTGAAGGATTACCAGAAATTTCTGATGTAGATACATTAG
GGGATTTGCTTGAAGAAATTGGAGGTAGTGTATCTAGAGATGGACAAGATATCACTATTCATCCTGAGAAGATGATGGCA
ATGCCTTTACCAAACGGCAAGGTTAAAAAACTTCGTGCATCCTATTATTTTATGGGGGCAATGCTTGGTAAATTTAACAA
AGCAGTAATTGGTTTACCTGGAGGATGTTTTTTAGGACCACGCCCAATAGATCAACATATCAAGGGTTTTGAAGCGCTGG
GTGCAGAGGTTACTAATGAACAAGGTGCAATTTACTTGCGAGCAAACGAATTGCGTGGAGCGCGTATCTATCTTGACGTT
GTTAGTGTTGGTGCAACGATAAATATTATGTTGGCAGCAGTAAAAGCAAAGGGAAGAACTACCATTGAGAATGCTGCTAA
AGAGCCAGAAATTATCGATGTAGCAACACTACTGACGAATATGGGAGCAAAAATTAAAGGTGTAGGTACCGACGTGATAC
GTATTGATGGAGTTCCTTCTTTACATGGTTGCCGTCATACGATTATTCCTGATCGAATAGAAGCTGGTACGTATGCAATT
GCTGCAGCAGCGAAAGGGAAGGAAGTAATTATTGATAATGTGATTCCACAGCATTTAGAATCACTAATTGCAAAACTTCG
TGAAATGGATGTAACCATTGAAGAAAGTGATGAACAATTATATATTGCACGAAACCGACCACTAAAGAGTGTGGATATTA
AAACGTTAGTATACCCTGGGTTTCCAACAGATTTACAACAACCATTTACTTCTTTACTAACACAAGCGACCCATTCTGGT
GTAATTACAGATACAATTTATTCTGCTAGACTAAAACATATTGATGAATTACGTAGGATGAATGCCGTAATTAAAGTTGA
AGGCGGGTCGGTGATCGTTTCCGGTCCTGTTCAATTAGAAGGTGCACGTGTAAAAGCAAGTGATCTTCGTGCAGGAGCAT
CTCTGATTATTGCTGGTCTGTTAGCTGATGGTATTACTGAAATAACTGGACTGGATCATATAGATAGAGGATATGAAAGA
TTAACAGAGAAATTATCTTCATTAGGCGCGAATATTTGGCGTGAAGAAATGACAGATATAGAAATAATGCAAGATCAAAA
TATGTAA

Upstream 100 bases:

>100_bases
TAAATTAGGAAACACTACAAATGTAATGATGTTAAACAAGCCTACTAACAACATACAGTGTGTTCAACAAAGAACACCTC
TTTAGGAATGAGGTTTTCAT

Downstream 100 bases:

>100_bases
ATATCCATTTCACACATTAACTATTACTTAATGGGATGAGTATAGGTAGATGTGTTCAAAAAGGTAGAATTTTTGACCAT
CCTCTAATAAAGGAAAGGGA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MQKLLIEGGHDLTGQVRISGAKNSAVALLPAAILADSAVTIEGLPEISDVDTLGDLLEEIGGSVSRDGQDITIHPEKMMA
MPLPNGKVKKLRASYYFMGAMLGKFNKAVIGLPGGCFLGPRPIDQHIKGFEALGAEVTNEQGAIYLRANELRGARIYLDV
VSVGATINIMLAAVKAKGRTTIENAAKEPEIIDVATLLTNMGAKIKGVGTDVIRIDGVPSLHGCRHTIIPDRIEAGTYAI
AAAAKGKEVIIDNVIPQHLESLIAKLREMDVTIEESDEQLYIARNRPLKSVDIKTLVYPGFPTDLQQPFTSLLTQATHSG
VITDTIYSARLKHIDELRRMNAVIKVEGGSVIVSGPVQLEGARVKASDLRAGASLIIAGLLADGITEITGLDHIDRGYER
LTEKLSSLGANIWREEMTDIEIMQDQNM

Sequences:

>Translated_428_residues
MQKLLIEGGHDLTGQVRISGAKNSAVALLPAAILADSAVTIEGLPEISDVDTLGDLLEEIGGSVSRDGQDITIHPEKMMA
MPLPNGKVKKLRASYYFMGAMLGKFNKAVIGLPGGCFLGPRPIDQHIKGFEALGAEVTNEQGAIYLRANELRGARIYLDV
VSVGATINIMLAAVKAKGRTTIENAAKEPEIIDVATLLTNMGAKIKGVGTDVIRIDGVPSLHGCRHTIIPDRIEAGTYAI
AAAAKGKEVIIDNVIPQHLESLIAKLREMDVTIEESDEQLYIARNRPLKSVDIKTLVYPGFPTDLQQPFTSLLTQATHSG
VITDTIYSARLKHIDELRRMNAVIKVEGGSVIVSGPVQLEGARVKASDLRAGASLIIAGLLADGITEITGLDHIDRGYER
LTEKLSSLGANIWREEMTDIEIMQDQNM
>Mature_428_residues
MQKLLIEGGHDLTGQVRISGAKNSAVALLPAAILADSAVTIEGLPEISDVDTLGDLLEEIGGSVSRDGQDITIHPEKMMA
MPLPNGKVKKLRASYYFMGAMLGKFNKAVIGLPGGCFLGPRPIDQHIKGFEALGAEVTNEQGAIYLRANELRGARIYLDV
VSVGATINIMLAAVKAKGRTTIENAAKEPEIIDVATLLTNMGAKIKGVGTDVIRIDGVPSLHGCRHTIIPDRIEAGTYAI
AAAAKGKEVIIDNVIPQHLESLIAKLREMDVTIEESDEQLYIARNRPLKSVDIKTLVYPGFPTDLQQPFTSLLTQATHSG
VITDTIYSARLKHIDELRRMNAVIKVEGGSVIVSGPVQLEGARVKASDLRAGASLIIAGLLADGITEITGLDHIDRGYER
LTEKLSSLGANIWREEMTDIEIMQDQNM

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=44.6300715990453, Blast_Score=342, Evalue=2e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA2_OCEIH (Q8EM55)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693925.1
- ProteinModelPortal:   Q8EM55
- SMR:   Q8EM55
- GeneID:   1016720
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB3003
- NMPDR:   fig|221109.1.peg.3005
- HOGENOM:   HBG482701
- OMA:   TDEIRIK
- ProtClustDB:   PRK12830
- BioCyc:   OIHE221109:OB3003-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 46038; Mature: 46038

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLLIEGGHDLTGQVRISGAKNSAVALLPAAILADSAVTIEGLPEISDVDTLGDLLEEI
CCCEEEECCCCCEEEEEEECCCCCEEEEHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHH
GGSVSRDGQDITIHPEKMMAMPLPNGKVKKLRASYYFMGAMLGKFNKAVIGLPGGCFLGP
CCCCCCCCCEEEECHHHEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
RPIDQHIKGFEALGAEVTNEQGAIYLRANELRGARIYLDVVSVGATINIMLAAVKAKGRT
CCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEEEEECCCCCC
TIENAAKEPEIIDVATLLTNMGAKIKGVGTDVIRIDGVPSLHGCRHTIIPDRIEAGTYAI
HHHHHCCCCCHHHHHHHHHHCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEE
AAAAKGKEVIIDNVIPQHLESLIAKLREMDVTIEESDEQLYIARNRPLKSVDIKTLVYPG
EEECCCCEEEEHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCEEEEEECC
FPTDLQQPFTSLLTQATHSGVITDTIYSARLKHIDELRRMNAVIKVEGGSVIVSGPVQLE
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCEEEC
GARVKASDLRAGASLIIAGLLADGITEITGLDHIDRGYERLTEKLSSLGANIWREEMTDI
CCEEEHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
EIMQDQNM
EEECCCCC
>Mature Secondary Structure
MQKLLIEGGHDLTGQVRISGAKNSAVALLPAAILADSAVTIEGLPEISDVDTLGDLLEEI
CCCEEEECCCCCEEEEEEECCCCCEEEEHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHH
GGSVSRDGQDITIHPEKMMAMPLPNGKVKKLRASYYFMGAMLGKFNKAVIGLPGGCFLGP
CCCCCCCCCEEEECHHHEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
RPIDQHIKGFEALGAEVTNEQGAIYLRANELRGARIYLDVVSVGATINIMLAAVKAKGRT
CCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEEEEECCCCCC
TIENAAKEPEIIDVATLLTNMGAKIKGVGTDVIRIDGVPSLHGCRHTIIPDRIEAGTYAI
HHHHHCCCCCHHHHHHHHHHCCCEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEE
AAAAKGKEVIIDNVIPQHLESLIAKLREMDVTIEESDEQLYIARNRPLKSVDIKTLVYPG
EEECCCCEEEEHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCEEEEEECC
FPTDLQQPFTSLLTQATHSGVITDTIYSARLKHIDELRRMNAVIKVEGGSVIVSGPVQLE
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCEEEC
GARVKASDLRAGASLIIAGLLADGITEITGLDHIDRGYERLTEKLSSLGANIWREEMTDI
CCEEEHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
EIMQDQNM
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376