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The map label for this gene is atpC

Identifier: 23100429

GI number: 23100429

Start: 3084884

End: 3085279

Strand: Reverse

Name: atpC

Synonym: OB2974

Alternate gene names: 23100429

Gene position: 3085279-3084884 (Counterclockwise)

Preceding gene: 23100430

Following gene: 23100428

Centisome position: 84.98

GC content: 39.39

Gene sequence:

>396_bases
TTGAGAACACTAGAAGTGAGTGTTGTTACTCCTGGTGGCCCGGTTTTAGAGGAAAGCTTTGAAATGGTAGTTTGTAAAGC
TGAAACCGGTGAAATCGGTATTTTACCTGGACACATTCCATTAGTTTCTCCACTACAAATTAGTGCAGTTCGTTTGAAAA
AAGGAAATGATACTAAATATTTAGCAATAAGTGGTGGATTTATGGAAGTGCAGCCTGAGAAAGTAACCATTCTTGCACAA
TCTGCTGAAACTGCAAGTGATATTAATGTTCAACGTGCAAAAGAAGCAAAAGATCGTGCGGAAAGACGTCTTCAGGCAAA
AAAGGATAATATCGATAAAACTCGGGCCGAATTAGCACTCAAAAGAGCAATTAATCGCCTCGACGTAGGCAAGTAA

Upstream 100 bases:

>100_bases
ATAATATTCGGTCGTGGAAGTAGGGATTTTGGAAAGAAAATCTTTTATTGCCTGAATTAATTTTTGGGCACTTCCATCCC
GTCTCTTAGGAGGGGTTACA

Downstream 100 bases:

>100_bases
TACTAAAAAACTCCTGCAATTATTATTGCGGGAGTTTTTTTGCTTTTAAGAAAGACTTTATATGGGCTTGGACCAGCTTG
CCTAGTAACATGCAGATATA

Product: H(+)-transporting ATP synthase epsilon chain

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F1 sector epsilon subunit; F-ATPase epsilon subunit

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MRTLEVSVVTPGGPVLEESFEMVVCKAETGEIGILPGHIPLVSPLQISAVRLKKGNDTKYLAISGGFMEVQPEKVTILAQ
SAETASDINVQRAKEAKDRAERRLQAKKDNIDKTRAELALKRAINRLDVGK

Sequences:

>Translated_131_residues
MRTLEVSVVTPGGPVLEESFEMVVCKAETGEIGILPGHIPLVSPLQISAVRLKKGNDTKYLAISGGFMEVQPEKVTILAQ
SAETASDINVQRAKEAKDRAERRLQAKKDNIDKTRAELALKRAINRLDVGK
>Mature_131_residues
MRTLEVSVVTPGGPVLEESFEMVVCKAETGEIGILPGHIPLVSPLQISAVRLKKGNDTKYLAISGGFMEVQPEKVTILAQ
SAETASDINVQRAKEAKDRAERRLQAKKDNIDKTRAELALKRAINRLDVGK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG0355

COG function: function code C; F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase epsilon chain family

Homologues:

Organism=Escherichia coli, GI1790169, Length=128, Percent_Identity=32.8125, Blast_Score=78, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPE_OCEIH (Q8EM84)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693896.1
- ProteinModelPortal:   Q8EM84
- SMR:   Q8EM84
- GeneID:   1016740
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2974
- NMPDR:   fig|221109.1.peg.2977
- HOGENOM:   HBG663981
- OMA:   EMVSVRA
- BioCyc:   OIHE221109:OB2974-MONOMER
- BRENDA:   3.6.3.14
- HAMAP:   MF_00530
- InterPro:   IPR001469
- InterPro:   IPR020547
- InterPro:   IPR020546
- Gene3D:   G3DSA:1.20.5.440
- Gene3D:   G3DSA:2.60.15.10
- PANTHER:   PTHR13822
- ProDom:   PD000944
- TIGRFAMs:   TIGR01216

Pfam domain/function: PF00401 ATP-synt_DE; PF02823 ATP-synt_DE_N; SSF46604 ATPsynt_DE; SSF51344 ATPsynt_DE

EC number: 3.6.3.14

Molecular weight: Translated: 14294; Mature: 14294

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLEVSVVTPGGPVLEESFEMVVCKAETGEIGILPGHIPLVSPLQISAVRLKKGNDTKY
CCEEEEEEECCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCEEEEEEEECCCCCEE
LAISGGFMEVQPEKVTILAQSAETASDINVQRAKEAKDRAERRLQAKKDNIDKTRAELAL
EEEECCEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KRAINRLDVGK
HHHHHHCCCCC
>Mature Secondary Structure
MRTLEVSVVTPGGPVLEESFEMVVCKAETGEIGILPGHIPLVSPLQISAVRLKKGNDTKY
CCEEEEEEECCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCEEEEEEEECCCCCEE
LAISGGFMEVQPEKVTILAQSAETASDINVQRAKEAKDRAERRLQAKKDNIDKTRAELAL
EEEECCEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KRAINRLDVGK
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12235376