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The map label for this gene is atpD

Identifier: 23100430

GI number: 23100430

Start: 3085376

End: 3086770

Strand: Reverse

Name: atpD

Synonym: OB2975

Alternate gene names: 23100430

Gene position: 3086770-3085376 (Counterclockwise)

Preceding gene: 23100431

Following gene: 23100429

Centisome position: 85.02

GC content: 41.43

Gene sequence:

>1395_bases
ATGAGCAAAGGACGCGTTACACAATTAATGGGACCAGTAGTCGATGTACGTTTTGAAGACGCTGAACTCCCAGCAGTAAA
TAATGCTTTAGTTGTCCGTAGTGACAGTGGTGAAGAACTAACACTAGAAGTAGCTCTTCATTTAGGTGACAATAGTGTAC
GTACCATCGCTATGTCTTCAACAGATGGTTTCAAACGTGGTGCAGAGGTGGAAAACCTTGGTCGTCCAATCTCAGTACCA
GTTGGTGACGTAACACTAGGCCGTGTATTTAACGTATTAGGTGAAAAAATCGATTTAGACGAACCTTTAGAAGAGGGAGT
TCGTCGCGATCCGATTCACCGTGAAGCACCAGACTTTGAAAACTTATCTACAGAAACAGAAATTTTAGAGACAGGTATTA
AAGTAGTTGACCTGTTAGCACCATATATCAAAGGTGGTAAAATTGGACTGTTTGGTGGAGCTGGTGTAGGTAAAACCGTA
TTAATCCAGGAATTAATTAATAATATCGCACAAGAACATGGTGGTATTTCTGTATTCGCGGGTGTTGGTGAACGTACTCG
TGAAGGGAATGACCTTTACTATGAAATGAGCGATTCTGGAGTTATTGCTAAAACAGCGATGGTATTTGGACAAATGAACG
AGCCACCTGGTGCACGTATGCGTGTAGCATTAACTGGCTTAACCATGGCAGAATACTTCCGTGATGAGCAAGGACAGGAT
GTATTATTGTTCGTTGATAATATCTTCCGTTTCACACAAGCAGGTTCTGAGGTATCCGCACTACTTGGTCGTATGCCATC
AGCGGTAGGTTATCAACCTACTCTAGCTACAGAAATGGGACAATTACAAGAGCGTATTACATCTACAGACAAAGGTTCTG
TAACATCTATTCAAGCAATTTATGTACCAGCGGATGACTATACGGATCCGGCGCCTGCTACAACATTTGCTCACTTAGAT
GCAACAACAAACCTTGATCGTAAATTATCTGAGCAAGGTATCTACCCTGCGGTGGATCCTTTAGAGTCTACCTCACGTGC
ACTCGATCCAGAAGTAGTTGGAAAAGAGCACTATGAAGTAGCAACTGAGGTACAGCAAACACTACAAAAATATCGTGAAC
TTCAAGATATTATCGCAATATTAGGTATGGATGAGTTAAGTGATGAAGATAAATTAGTCGTTGCTCGTGCGCGTCGAATT
CAGTTCTTCCTATCACAAAACTTCCACGTAGCGGAGCAATTTACTGGACAACCTGGATCTTATGTTCCTGTTCAAGAGAC
TGTAAAAGGATTTAAAGAGATTCTTGAAGGTAAATATGACGATCTTCCAGAGGATGCTTTCCGTCTAGTTGGACGTATTG
AAGAAGTAGTAGAAAAAGCAAAAGGAATGGAATAA

Upstream 100 bases:

>100_bases
TCAAGCAGCAATTACACAAGAAATCACAGAGATTGTTGGTGGCGTAGCAGCACTCGAATAGGTTTAACACCGTGTGGACA
GTAAGTTAGGAGGGAAATAG

Downstream 100 bases:

>100_bases
TATTCGGTCGTGGAAGTAGGGATTTTGGAAAGAAAATCTTTTATTGCCTGAATTAATTTTTGGGCACTTCCATCCCGTCT
CTTAGGAGGGGTTACATTGA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSKGRVTQLMGPVVDVRFEDAELPAVNNALVVRSDSGEELTLEVALHLGDNSVRTIAMSSTDGFKRGAEVENLGRPISVP
VGDVTLGRVFNVLGEKIDLDEPLEEGVRRDPIHREAPDFENLSTETEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTV
LIQELINNIAQEHGGISVFAGVGERTREGNDLYYEMSDSGVIAKTAMVFGQMNEPPGARMRVALTGLTMAEYFRDEQGQD
VLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTDKGSVTSIQAIYVPADDYTDPAPATTFAHLD
ATTNLDRKLSEQGIYPAVDPLESTSRALDPEVVGKEHYEVATEVQQTLQKYRELQDIIAILGMDELSDEDKLVVARARRI
QFFLSQNFHVAEQFTGQPGSYVPVQETVKGFKEILEGKYDDLPEDAFRLVGRIEEVVEKAKGME

Sequences:

>Translated_464_residues
MSKGRVTQLMGPVVDVRFEDAELPAVNNALVVRSDSGEELTLEVALHLGDNSVRTIAMSSTDGFKRGAEVENLGRPISVP
VGDVTLGRVFNVLGEKIDLDEPLEEGVRRDPIHREAPDFENLSTETEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTV
LIQELINNIAQEHGGISVFAGVGERTREGNDLYYEMSDSGVIAKTAMVFGQMNEPPGARMRVALTGLTMAEYFRDEQGQD
VLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTDKGSVTSIQAIYVPADDYTDPAPATTFAHLD
ATTNLDRKLSEQGIYPAVDPLESTSRALDPEVVGKEHYEVATEVQQTLQKYRELQDIIAILGMDELSDEDKLVVARARRI
QFFLSQNFHVAEQFTGQPGSYVPVQETVKGFKEILEGKYDDLPEDAFRLVGRIEEVVEKAKGME
>Mature_463_residues
SKGRVTQLMGPVVDVRFEDAELPAVNNALVVRSDSGEELTLEVALHLGDNSVRTIAMSSTDGFKRGAEVENLGRPISVPV
GDVTLGRVFNVLGEKIDLDEPLEEGVRRDPIHREAPDFENLSTETEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVL
IQELINNIAQEHGGISVFAGVGERTREGNDLYYEMSDSGVIAKTAMVFGQMNEPPGARMRVALTGLTMAEYFRDEQGQDV
LLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTDKGSVTSIQAIYVPADDYTDPAPATTFAHLDA
TTNLDRKLSEQGIYPAVDPLESTSRALDPEVVGKEHYEVATEVQQTLQKYRELQDIIAILGMDELSDEDKLVVARARRIQ
FFLSQNFHVAEQFTGQPGSYVPVQETVKGFKEILEGKYDDLPEDAFRLVGRIEEVVEKAKGME

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=465, Percent_Identity=68.6021505376344, Blast_Score=632, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=361, Percent_Identity=29.0858725761773, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI19913426, Length=357, Percent_Identity=24.6498599439776, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI19913428, Length=354, Percent_Identity=24.2937853107345, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI50345984, Length=374, Percent_Identity=25.9358288770053, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4757810, Length=374, Percent_Identity=25.9358288770053, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1790170, Length=463, Percent_Identity=66.9546436285097, Blast_Score=615, Evalue=1e-177,
Organism=Escherichia coli, GI1788251, Length=408, Percent_Identity=27.4509803921569, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1790172, Length=357, Percent_Identity=27.4509803921569, Blast_Score=108, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=466, Percent_Identity=66.0944206008584, Blast_Score=607, Evalue=1e-174,
Organism=Caenorhabditis elegans, GI17565854, Length=353, Percent_Identity=29.4617563739377, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17510931, Length=406, Percent_Identity=23.1527093596059, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=412, Percent_Identity=22.8155339805825, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71988080, Length=378, Percent_Identity=25.9259259259259, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=378, Percent_Identity=25.9259259259259, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71988074, Length=330, Percent_Identity=25.4545454545455, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322581, Length=459, Percent_Identity=70.5882352941177, Blast_Score=646, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=416, Percent_Identity=24.0384615384615, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320016, Length=234, Percent_Identity=30.3418803418803, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319370, Length=378, Percent_Identity=27.2486772486773, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24638766, Length=464, Percent_Identity=68.9655172413793, Blast_Score=629, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=468, Percent_Identity=66.2393162393162, Blast_Score=605, Evalue=1e-173,
Organism=Drosophila melanogaster, GI20129479, Length=347, Percent_Identity=28.5302593659942, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24583988, Length=353, Percent_Identity=28.6118980169972, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24583986, Length=353, Percent_Identity=28.6118980169972, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24583984, Length=353, Percent_Identity=28.6118980169972, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24583992, Length=322, Percent_Identity=29.1925465838509, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281361666, Length=394, Percent_Identity=24.3654822335025, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24646341, Length=394, Percent_Identity=24.3654822335025, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17136796, Length=394, Percent_Identity=24.3654822335025, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24658560, Length=378, Percent_Identity=27.2486772486773, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24638768, Length=93, Percent_Identity=51.6129032258064, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_OCEIH (Q8EM83)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693897.1
- HSSP:   P07677
- ProteinModelPortal:   Q8EM83
- SMR:   Q8EM83
- GeneID:   1017924
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2975
- NMPDR:   fig|221109.1.peg.2978
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- ProtClustDB:   PRK09280
- BioCyc:   OIHE221109:OB2975-MONOMER
- BRENDA:   3.6.3.14
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 50788; Mature: 50657

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKGRVTQLMGPVVDVRFEDAELPAVNNALVVRSDSGEELTLEVALHLGDNSVRTIAMSS
CCCCCHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCCEEEEEEEEEECCCCEEEEEEEC
TDGFKRGAEVENLGRPISVPVGDVTLGRVFNVLGEKIDLDEPLEEGVRRDPIHREAPDFE
CCCHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCC
NLSTETEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFA
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEE
GVGERTREGNDLYYEMSDSGVIAKTAMVFGQMNEPPGARMRVALTGLTMAEYFRDEQGQD
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHCCCCCCE
VLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTDKGSVTSIQAI
EEEEHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEE
YVPADDYTDPAPATTFAHLDATTNLDRKLSEQGIYPAVDPLESTSRALDPEVVGKEHYEV
EECCCCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCCCHHHHHHHCCHHHCCCHHHHH
ATEVQQTLQKYRELQDIIAILGMDELSDEDKLVVARARRIQFFLSQNFHVAEQFTGQPGS
HHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCEEHHHHCCCCCC
YVPVQETVKGFKEILEGKYDDLPEDAFRLVGRIEEVVEKAKGME
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKGRVTQLMGPVVDVRFEDAELPAVNNALVVRSDSGEELTLEVALHLGDNSVRTIAMSS
CCCCHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCCEEEEEEEEEECCCCEEEEEEEC
TDGFKRGAEVENLGRPISVPVGDVTLGRVFNVLGEKIDLDEPLEEGVRRDPIHREAPDFE
CCCHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCC
NLSTETEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFA
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEE
GVGERTREGNDLYYEMSDSGVIAKTAMVFGQMNEPPGARMRVALTGLTMAEYFRDEQGQD
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHCCCCCCE
VLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTDKGSVTSIQAI
EEEEHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEE
YVPADDYTDPAPATTFAHLDATTNLDRKLSEQGIYPAVDPLESTSRALDPEVVGKEHYEV
EECCCCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCCCHHHHHHHCCHHHCCCHHHHH
ATEVQQTLQKYRELQDIIAILGMDELSDEDKLVVARARRIQFFLSQNFHVAEQFTGQPGS
HHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCCEEHHHHCCCCCC
YVPVQETVKGFKEILEGKYDDLPEDAFRLVGRIEEVVEKAKGME
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12235376