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The map label for this gene is dapA [H]

Identifier: 23100322

GI number: 23100322

Start: 2951684

End: 2952610

Strand: Reverse

Name: dapA [H]

Synonym: OB2867

Alternate gene names: 23100322

Gene position: 2952610-2951684 (Counterclockwise)

Preceding gene: 23100323

Following gene: 23100321

Centisome position: 81.33

GC content: 39.16

Gene sequence:

>927_bases
ATGAGTACGAAATACGATGCTATAAAAAAAAGATTGAGAGGTTCAATCGCACCGGTAATCACACCATTTAAAGTGAACGG
AGATATTGATTTTAAAAAACAGTCTGAATTAATCGAGTTTCAAATTGAAAATGGAACACATGCGATTTCTGTAACGGGTA
CTTCTGGAGAACCAAGCTCGCTTACTACAGAAGAGCGTGTTCAAGTAATGGAAAATGCAATCAAAACTATTAATGGTAGA
ATTCCGTTCGCTCCGGGAACTGGATCTACTAACCATGATGAAACAATGTACGTAACAAAGAAAGCGGAAGAAATGGGCGC
AGATGCCGCAATGGTTATTGTTCCTTATTATAATAAACCAAACCAGGAAGCATTGTATGATCATTTCAAAACAGTAGCTG
ATTCCGTAGATATTCCGATTATCATCTATAATATACCAGGACGGACTGCGCAAAATATGGAAGTGAAAACGATGGCGCGT
CTAGTAAAAGATTGTCCTAATATTGTTGGAGCGAAGGAATCAAATAAAGACTTTGAACATGTTAATAGAGTATTGCTTAA
CTGTGGCAGAGACTTCTTATTGTTTTCAGGAATTGAACTTTTATGCTACCCAATGCTAGCAATTGGAGGAGCTGGATCCA
TTAGTGCAACAGCTAACGTGGAGCCTAAGAAGGTAGCAGAAATGCATAATGCTTGGGAAGAAGGGGACATCAAACGAGCG
CAGGATCTTCACTTTGAATTAATGAACCTAAATGATGTGCTGTTTAAAGATACAAACCCTGCCCCAGTGAAAGCTGCACT
CGGAATGATGGGCATGATTGAACCCGTATTACGTAGACCAATGGGATTGCCTTCAGATGCATTGCAAGAAGAAATTCGTG
ACACCCTTGTGAAATACGGAAAAATAGAAAAAATAGCTTCGGTTTAG

Upstream 100 bases:

>100_bases
AAAATTGACACCAAACAGCCAACATTAGAAAAAAGAAAACCAAGCACCGTAATATAAATAATCTATATATTTAGCAATCT
AACAGGAGGTTATATATAAA

Downstream 100 bases:

>100_bases
ATTAATAGATTTATATGAGGAAATTGAATGAAGACCAGTAAGCTACTGGTCTCTTTTTCTTCATTTAGACTGTACATTTT
CTAAAAACATTAAAGGAGTG

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSTKYDAIKKRLRGSIAPVITPFKVNGDIDFKKQSELIEFQIENGTHAISVTGTSGEPSSLTTEERVQVMENAIKTINGR
IPFAPGTGSTNHDETMYVTKKAEEMGADAAMVIVPYYNKPNQEALYDHFKTVADSVDIPIIIYNIPGRTAQNMEVKTMAR
LVKDCPNIVGAKESNKDFEHVNRVLLNCGRDFLLFSGIELLCYPMLAIGGAGSISATANVEPKKVAEMHNAWEEGDIKRA
QDLHFELMNLNDVLFKDTNPAPVKAALGMMGMIEPVLRRPMGLPSDALQEEIRDTLVKYGKIEKIASV

Sequences:

>Translated_308_residues
MSTKYDAIKKRLRGSIAPVITPFKVNGDIDFKKQSELIEFQIENGTHAISVTGTSGEPSSLTTEERVQVMENAIKTINGR
IPFAPGTGSTNHDETMYVTKKAEEMGADAAMVIVPYYNKPNQEALYDHFKTVADSVDIPIIIYNIPGRTAQNMEVKTMAR
LVKDCPNIVGAKESNKDFEHVNRVLLNCGRDFLLFSGIELLCYPMLAIGGAGSISATANVEPKKVAEMHNAWEEGDIKRA
QDLHFELMNLNDVLFKDTNPAPVKAALGMMGMIEPVLRRPMGLPSDALQEEIRDTLVKYGKIEKIASV
>Mature_307_residues
STKYDAIKKRLRGSIAPVITPFKVNGDIDFKKQSELIEFQIENGTHAISVTGTSGEPSSLTTEERVQVMENAIKTINGRI
PFAPGTGSTNHDETMYVTKKAEEMGADAAMVIVPYYNKPNQEALYDHFKTVADSVDIPIIIYNIPGRTAQNMEVKTMARL
VKDCPNIVGAKESNKDFEHVNRVLLNCGRDFLLFSGIELLCYPMLAIGGAGSISATANVEPKKVAEMHNAWEEGDIKRAQ
DLHFELMNLNDVLFKDTNPAPVKAALGMMGMIEPVLRRPMGLPSDALQEEIRDTLVKYGKIEKIASV

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=288, Percent_Identity=27.0833333333333, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI13540533, Length=293, Percent_Identity=27.9863481228669, Blast_Score=101, Evalue=7e-22,
Organism=Escherichia coli, GI1788823, Length=288, Percent_Identity=35.0694444444444, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI87082415, Length=245, Percent_Identity=33.469387755102, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1786463, Length=248, Percent_Identity=32.258064516129, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1789620, Length=277, Percent_Identity=27.7978339350181, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33989; Mature: 33857

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKYDAIKKRLRGSIAPVITPFKVNGDIDFKKQSELIEFQIENGTHAISVTGTSGEPSS
CCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCC
LTTEERVQVMENAIKTINGRIPFAPGTGSTNHDETMYVTKKAEEMGADAAMVIVPYYNKP
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECHHHHCCCEEEEEEECCCCC
NQEALYDHFKTVADSVDIPIIIYNIPGRTAQNMEVKTMARLVKDCPNIVGAKESNKDFEH
CHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCHHHH
VNRVLLNCGRDFLLFSGIELLCYPMLAIGGAGSISATANVEPKKVAEMHNAWEEGDIKRA
HHHHHHHCCCHHHHHHCHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHCCCCCHHH
QDLHFELMNLNDVLFKDTNPAPVKAALGMMGMIEPVLRRPMGLPSDALQEEIRDTLVKYG
HHHHHEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
KIEKIASV
CHHHHHCC
>Mature Secondary Structure 
STKYDAIKKRLRGSIAPVITPFKVNGDIDFKKQSELIEFQIENGTHAISVTGTSGEPSS
CCHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCC
LTTEERVQVMENAIKTINGRIPFAPGTGSTNHDETMYVTKKAEEMGADAAMVIVPYYNKP
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECHHHHCCCEEEEEEECCCCC
NQEALYDHFKTVADSVDIPIIIYNIPGRTAQNMEVKTMARLVKDCPNIVGAKESNKDFEH
CHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCHHHH
VNRVLLNCGRDFLLFSGIELLCYPMLAIGGAGSISATANVEPKKVAEMHNAWEEGDIKRA
HHHHHHHCCCHHHHHHCHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHCCCCCHHH
QDLHFELMNLNDVLFKDTNPAPVKAALGMMGMIEPVLRRPMGLPSDALQEEIRDTLVKYG
HHHHHEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
KIEKIASV
CHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA